STRINGSTRING
tpiA tpiA apgM apgM Py04_0173 Py04_0173 Py04_0181 Py04_0181 pgiA pgiA eno eno Py04_0387 Py04_0387 pckG pckG glkA glkA Py04_0640 Py04_0640 Py04_0710 Py04_0710 fbp fbp Py04_0858 Py04_0858 Py04_1009 Py04_1009 Py04_1076 Py04_1076 Py04_1077 Py04_1077 Py04_1078 Py04_1078 Py04_1082 Py04_1082 Py04_1124 Py04_1124 Py04_1410 Py04_1410 Py04_1522 Py04_1522 pfkC pfkC Py04_1550 Py04_1550 Py04_1551 Py04_1551 Py04_1553 Py04_1553 Py04_1554 Py04_1554 Py04_1668 Py04_1668 Py04_1719 Py04_1719 gap gap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tpiAPutative triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (229 aa)
apgMCofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
Py04_0173Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (816 aa)
Py04_0181Fructose 1,6-bisphosphate aldolase; COG1830. (281 aa)
pgiAGlucose-6-phosphate isomerase; COG2140; Belongs to the archaeal-type GPI family. (189 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
Py04_0387Putative succinyl-coA synthetase alpha subunit related protein; COG1042. (437 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (624 aa)
glkAADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (455 aa)
Py04_0640Glyceraldehyde-3-phosphate: ferredoxin oxidoreductase; COG2414. (653 aa)
Py04_0710Hypothetical protein; COG1042. (457 aa)
fbpPutative fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
Py04_0858Phospho-sugar mutase; COG1109. (456 aa)
Py04_1009Phosphoglycerate kinase; COG0126. (358 aa)
Py04_1076Pyruvate ferredoxin oxidoreductase subunit beta; COG1013. (331 aa)
Py04_1077Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674. (396 aa)
Py04_1078Pyuvate ferredoxin oxidoreductase subunit delta; COG1144. (105 aa)
Py04_1082Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014. (185 aa)
Py04_1124Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (476 aa)
Py04_1410ADP forming acetyl coenzyme A synthetase; COG1042. (411 aa)
Py04_1522Putative eno-like enolase; COG0148. (341 aa)
pfkCADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (458 aa)
Py04_15502-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (281 aa)
Py04_15512-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (385 aa)
Py04_15532-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (280 aa)
Py04_15542-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (397 aa)
Py04_1668acetyl-CoA synthetase I subunit beta; COG1042. (232 aa)
Py04_1719Putative acetyl-CoA synthetase subunit beta; COG1042. (252 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; COG0057. (334 aa)
Your Current Organism:
Pyrococcus sp. ST04
NCBI taxonomy Id: 1183377
Other names: P. sp. ST04
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.