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ppcA ppcA Py04_0173 Py04_0173 Py04_0387 Py04_0387 Py04_0433 Py04_0433 pckG pckG Py04_0710 Py04_0710 Py04_0757 Py04_0757 leuA leuA Py04_0853 Py04_0853 Py04_0912 Py04_0912 Py04_0931 Py04_0931 Py04_0982 Py04_0982 Py04_1076 Py04_1076 Py04_1077 Py04_1077 Py04_1078 Py04_1078 Py04_1082 Py04_1082 Py04_1084 Py04_1084 Py04_1124 Py04_1124 Py04_1410 Py04_1410 Py04_1550 Py04_1550 Py04_1551 Py04_1551 Py04_1553 Py04_1553 Py04_1554 Py04_1554 Py04_1574 Py04_1574 Py04_1575 Py04_1575 Py04_1668 Py04_1668 Py04_1719 Py04_1719
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (464 aa)
Py04_0173Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (816 aa)
Py04_0387Putative succinyl-coA synthetase alpha subunit related protein; COG1042. (437 aa)
Py04_0433Acylphosphatase; COG1254. (91 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (624 aa)
Py04_0710Hypothetical protein; COG1042. (457 aa)
Py04_0757methylmalonyl-CoA decarboxylase subunit beta; COG1883. (400 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). (499 aa)
Py04_0853Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)
Py04_0912Putative hydroxyacylglutathione hydrolase (glyoxalase II); COG0491. (227 aa)
Py04_0931Pyruvate carboxylase subunit B; COG5016. (468 aa)
Py04_0982Malate dehydrogenase; COG0281. (434 aa)
Py04_1076Pyruvate ferredoxin oxidoreductase subunit beta; COG1013. (331 aa)
Py04_1077Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674. (396 aa)
Py04_1078Pyuvate ferredoxin oxidoreductase subunit delta; COG1144. (105 aa)
Py04_1082Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014. (185 aa)
Py04_1084acetyl-CoA acetyltransferase; COG0183. (388 aa)
Py04_1124Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (476 aa)
Py04_1410ADP forming acetyl coenzyme A synthetase; COG1042. (411 aa)
Py04_15502-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (281 aa)
Py04_15512-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (385 aa)
Py04_15532-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (280 aa)
Py04_15542-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (397 aa)
Py04_1574Fumarate hydratase (fumarase) alpha subunit; COG1951. (276 aa)
Py04_1575Fumarate hydratase (fumarase) beta subunit; COG1838. (166 aa)
Py04_1668acetyl-CoA synthetase I subunit beta; COG1042. (232 aa)
Py04_1719Putative acetyl-CoA synthetase subunit beta; COG1042. (252 aa)
Your Current Organism:
Pyrococcus sp. ST04
NCBI taxonomy Id: 1183377
Other names: P. sp. ST04
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