(19 nodes) Butanoate metabolism network (Pyrococcus sp. ST04)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Py04_0695	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
	Py04_0757	methylmalonyl-CoA decarboxylase subunit beta; COG1883. (400 aa)
	Py04_0758	Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; COG0511. (144 aa)
	Py04_0759	Putative Methylmalonyl-CoA decarboxylase subunit delta; COG3630. (124 aa)
	Py04_0847	Acetolactate synthase, large subunit; COG0028. (534 aa)
	Py04_0947	Arylmalonate decarboxylase; COG3473. (236 aa)
	Py04_0997	Putative acetolactate synthase small subunit; COG0440. (139 aa)
	Py04_1076	Pyruvate ferredoxin oxidoreductase subunit beta; COG1013. (331 aa)
	Py04_1077	Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674. (396 aa)
	Py04_1078	Pyuvate ferredoxin oxidoreductase subunit delta; COG1144. (105 aa)
	Py04_1082	Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014. (185 aa)
	Py04_1083	Putative 3-hydroxy-3-methylglutaryl CoA synthase; COG3425; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)
	Py04_1084	acetyl-CoA acetyltransferase; COG0183. (388 aa)
	Py04_1327	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
	Py04_1388	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	Py04_1550	2-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (281 aa)
	Py04_1551	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (385 aa)
	Py04_1553	2-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013. (280 aa)
	Py04_1554	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674. (397 aa)

Your Current Organism:

Pyrococcus sp. ST04

NCBI taxonomy Id: 1183377
Other names: P. sp. ST04

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
Py04_0695	Py04_1327	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.906
Py04_0695	Py04_1388	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.906
Py04_0757	Py04_0758	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; COG0511.	0.993
Py04_0757	Py04_0759	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Putative Methylmalonyl-CoA decarboxylase subunit delta; COG3630.	0.992
Py04_0757	Py04_0847	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Acetolactate synthase, large subunit; COG0028.	0.814
Py04_0757	Py04_0997	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Putative acetolactate synthase small subunit; COG0440.	0.800
Py04_0757	Py04_1076	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Pyruvate ferredoxin oxidoreductase subunit beta; COG1013.	0.902
Py04_0757	Py04_1077	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674.	0.908
Py04_0757	Py04_1078	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Pyuvate ferredoxin oxidoreductase subunit delta; COG1144.	0.900
Py04_0757	Py04_1082	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014.	0.901
Py04_0757	Py04_1550	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	2-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013.	0.902
Py04_0757	Py04_1551	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674.	0.908
Py04_0757	Py04_1553	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	2-oxoglutarate ferredoxin oxidoreductase subunit beta; COG1013.	0.902
Py04_0757	Py04_1554	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; COG0674.	0.908
Py04_0758	Py04_0757	Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; COG0511.	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	0.993
Py04_0758	Py04_0759	Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; COG0511.	Putative Methylmalonyl-CoA decarboxylase subunit delta; COG3630.	0.984
Py04_0759	Py04_0757	Putative Methylmalonyl-CoA decarboxylase subunit delta; COG3630.	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	0.992
Py04_0759	Py04_0758	Putative Methylmalonyl-CoA decarboxylase subunit delta; COG3630.	Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; COG0511.	0.984
Py04_0847	Py04_0757	Acetolactate synthase, large subunit; COG0028.	methylmalonyl-CoA decarboxylase subunit beta; COG1883.	0.814
Py04_0847	Py04_0997	Acetolactate synthase, large subunit; COG0028.	Putative acetolactate synthase small subunit; COG0440.	0.999