STRINGSTRING
Py04_0019 Py04_0019 ppcA ppcA apgM apgM Py04_0173 Py04_0173 Py04_0181 Py04_0181 eno eno Py04_0376 Py04_0376 Py04_0545 Py04_0545 glkA glkA fbp fbp Py04_0831 Py04_0831 Py04_1076 Py04_1076 Py04_1077 Py04_1077 Py04_1078 Py04_1078 Py04_1082 Py04_1082 mfnA mfnA Py04_1234 Py04_1234 Py04_1357 Py04_1357 Py04_1522 Py04_1522 pfkC pfkC glyA glyA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Py04_0019Putative phosphoserine phosphatase; COG0560. (208 aa)
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (464 aa)
apgMCofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
Py04_0173Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (816 aa)
Py04_0181Fructose 1,6-bisphosphate aldolase; COG1830. (281 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
Py04_0376D-arabino 3-hexulose 6-phosphate formaldehyde lyase; COG0269. (406 aa)
Py04_0545Putative glycerate kinase; COG2379. (434 aa)
glkAADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (455 aa)
fbpPutative fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
Py04_0831Formylmethanofuran dehydrogenase subunit E; COG2191. (231 aa)
Py04_1076Pyruvate ferredoxin oxidoreductase subunit beta; COG1013. (331 aa)
Py04_1077Pyruvate ferredoxin oxidoreductase subunit alpha; COG0674. (396 aa)
Py04_1078Pyuvate ferredoxin oxidoreductase subunit delta; COG1144. (105 aa)
Py04_1082Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; COG1014. (185 aa)
mfnAL-tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (367 aa)
Py04_1234Putative formate dehydrogenase alpha subunit related protein; COG0243. (653 aa)
Py04_1357D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (304 aa)
Py04_1522Putative eno-like enolase; COG0148. (341 aa)
pfkCADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (458 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
Your Current Organism:
Pyrococcus sp. ST04
NCBI taxonomy Id: 1183377
Other names: P. sp. ST04
Server load: low (28%) [HD]