(64 nodes) His Kinase A (phosphoacceptor) domain, and OmpR/PhoB-type DNA-binding domain network (Gloeobacter kilaueensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	arcB	Aerobic respiration control sensor histidine kinase ArcB; COG0642. (738 aa)
	GKIL_0138	Multi-sensor hybrid histidine kinase; COG0642. (734 aa)
	cheR	Signal transduction histidine kinase with CheB and CheR activity; COG1352. (1234 aa)
	GKIL_0437	Multi-sensor hybrid histidine kinase; COG0642. (386 aa)
	GKIL_0439	Multi-sensor signal transduction histidine kinase; COG4251. (601 aa)
	GKIL_0634	Multi-sensor signal transduction histidine kinase; COG2205. (386 aa)
	GKIL_0635	Signal transduction histidine kinase; COG3920. (763 aa)
	GKIL_0933	Response regulator receiver protein; COG0745. (147 aa)
	cph1	Multi-sensor signal transduction histidine kinase; COG4251. (497 aa)
	pleD-2	Multi-sensor hybrid histidine kinase; COG0642. (494 aa)
	pleD-3	Multi-sensor hybrid histidine kinase; COG0642. (584 aa)
	phoB	Two component transcriptional regulator, winged helix family; COG0745. (234 aa)
	GKIL_1231	Sensor histidine kinase; COG5002. (296 aa)
	GKIL_1341	Multi-sensor signal transduction histidine kinase; COG0642. (592 aa)
	phoB1	Two component transcriptional regulator, winged helix family; COG0745. (229 aa)
	pleD-4	Diguanylate cyclase; COG2199. (979 aa)
	GKIL_1503	Two component transcriptional regulator, winged helix family; COG0745. (222 aa)
	phoR	Histidine kinase; COG0642. (360 aa)
	GKIL_1845	Two component transcriptional regulator, winged helix family; COG0745. (234 aa)
	atoS	Sensor protein ZraS; COG0642. (406 aa)
	GKIL_2025	Multi-sensor hybrid histidine kinase; COG0642. (615 aa)
	GKIL_2138	Multi-sensor hybrid histidine kinase; COG0642. (1275 aa)
	rpaB	Two-component response regulator; COG0745. (246 aa)
	GKIL_2251	Two component transcriptional regulator, winged helix family; COG0745. (596 aa)
	GKIL_2252	Multi-sensor signal transduction histidine kinase; COG5002. (543 aa)
	GKIL_2253	Response regulator receiver protein; COG0745. (124 aa)
	pleD-5	Multi-sensor signal transduction histidine kinase; COG3920. (1134 aa)
	GKIL_2255	Response regulator receiver sensor signal transduction histidine kinase; COG0642. (403 aa)
	pleD-6	Response regulator receiver sensor signal transduction histidine kinase; COG0642. (357 aa)
	pleD-7	GAF sensor hybrid histidine kinase; COG0642. (1597 aa)
	pleD-8	Multi-sensor hybrid histidine kinase; COG0642. (541 aa)
	GKIL_2875	Multi-sensor hybrid histidine kinase; COG0642. (565 aa)
	GKIL_2884	Two component transcriptional regulator, winged helix family; COG0745. (629 aa)
	GKIL_2886	Multi-sensor signal transduction histidine kinase; COG5002. (368 aa)
	pleD-9	Response regulator receiver protein; COG0745. (140 aa)
	GKIL_2905	Multi-sensor signal transduction histidine kinase; COG5002. (683 aa)
	trxB-3	Thioredoxin reductase; COG0492. (555 aa)
	GKIL_2948	Histidine kinase; COG0642. (460 aa)
	dctB	Two-component sensor histidine kinase; COG4191. (477 aa)
	GKIL_2973	Two-component sensor histidine kinase; COG2205. (497 aa)
	GKIL_2974	Two-component response regulator; COG2197. (228 aa)
	GKIL_3045	Multi-sensor signal transduction histidine kinase; COG5002. (712 aa)
	GKIL_3047	Hypothetical protein. (560 aa)
	pleC	Cell cycle sensor histidine kinase PleC; COG0642. (620 aa)
	GKIL_3269	Multi-sensor hybrid histidine kinase; COG0642. (534 aa)
	GKIL_3342	Histidine kinase; COG0642. (368 aa)
	pleD-10	Diguanylate cyclase; COG3706. (460 aa)
	GKIL_3511	NtrC family sensor kinase; COG0642. (425 aa)
	qseB	Two component transcriptional regulator, winged helix family; COG0745. (230 aa)
	pleD-12	Hybrid sensory kinase in two-component regulatory system with RcsB and YojN; COG0745. (119 aa)
	GKIL_3733	Hypothetical protein; COG2205. (74 aa)
	GKIL_3734	Two component transcriptional regulator, winged helix family; COG0745. (230 aa)
	GKIL_3776	Two-component sensor histidine kinase; COG0642. (454 aa)
	GKIL_3777	Two component transcriptional regulator, winged helix family; COG0745. (223 aa)
	GKIL_3993	Sensory box/GGDEF family protein; COG2200. (300 aa)
	pleD-13	Multi-sensor hybrid histidine kinase; COG0642. (1117 aa)
	phoB1-2	Two component transcriptional regulator, winged helix family; COG0745. (239 aa)
	GKIL_4323	Histidine kinase; COG4585. (607 aa)
	nblS	Multi-sensor signal transduction histidine kinase; COG5002. (626 aa)
	GKIL_4448	Two-component response regulator; COG0745. (330 aa)
	phoR-2	Multi-sensor signal transduction histidine kinase; COG2205. (336 aa)
	rpaA	Two component transcriptional regulator, winged helix family; COG0745. (242 aa)
	pleD-14	Response regulator receiver protein; COG0745. (132 aa)
	manS	OmpR family manganese sensing sensor histidine kinase; COG5002. (449 aa)

Your Current Organism:

Gloeobacter kilaueensis

NCBI taxonomy Id: 1183438
Other names: G. kilaueensis JS1, Gloeobacter kilaueensis JS1, Gloeobacter sp. JS

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GKIL_0138	GKIL_0437	GKIL_0138	GKIL_0437	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor hybrid histidine kinase; COG0642.	0.666
GKIL_0138	GKIL_0439	GKIL_0138	GKIL_0439	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor signal transduction histidine kinase; COG4251.	0.846
GKIL_0138	GKIL_0634	GKIL_0138	GKIL_0634	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor signal transduction histidine kinase; COG2205.	0.466
GKIL_0138	GKIL_0635	GKIL_0138	GKIL_0635	Multi-sensor hybrid histidine kinase; COG0642.	Signal transduction histidine kinase; COG3920.	0.528
GKIL_0138	GKIL_0933	GKIL_0138	GKIL_0933	Multi-sensor hybrid histidine kinase; COG0642.	Response regulator receiver protein; COG0745.	0.625
GKIL_0138	GKIL_1503	GKIL_0138	GKIL_1503	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.686
GKIL_0138	GKIL_1845	GKIL_0138	GKIL_1845	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.740
GKIL_0138	GKIL_2025	GKIL_0138	GKIL_2025	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor hybrid histidine kinase; COG0642.	0.545
GKIL_0138	GKIL_2138	GKIL_0138	GKIL_2138	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor hybrid histidine kinase; COG0642.	0.854
GKIL_0138	GKIL_2251	GKIL_0138	GKIL_2251	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.912
GKIL_0138	GKIL_2253	GKIL_0138	GKIL_2253	Multi-sensor hybrid histidine kinase; COG0642.	Response regulator receiver protein; COG0745.	0.803
GKIL_0138	GKIL_2255	GKIL_0138	GKIL_2255	Multi-sensor hybrid histidine kinase; COG0642.	Response regulator receiver sensor signal transduction histidine kinase; COG0642.	0.632
GKIL_0138	GKIL_2884	GKIL_0138	GKIL_2884	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.998
GKIL_0138	GKIL_2886	GKIL_0138	GKIL_2886	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor signal transduction histidine kinase; COG5002.	0.667
GKIL_0138	GKIL_2905	GKIL_0138	GKIL_2905	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor signal transduction histidine kinase; COG5002.	0.552
GKIL_0138	GKIL_2973	GKIL_0138	GKIL_2973	Multi-sensor hybrid histidine kinase; COG0642.	Two-component sensor histidine kinase; COG2205.	0.628
GKIL_0138	GKIL_3269	GKIL_0138	GKIL_3269	Multi-sensor hybrid histidine kinase; COG0642.	Multi-sensor hybrid histidine kinase; COG0642.	0.809
GKIL_0138	GKIL_3734	GKIL_0138	GKIL_3734	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.706
GKIL_0138	GKIL_3777	GKIL_0138	GKIL_3777	Multi-sensor hybrid histidine kinase; COG0642.	Two component transcriptional regulator, winged helix family; COG0745.	0.679
GKIL_0138	GKIL_3993	GKIL_0138	GKIL_3993	Multi-sensor hybrid histidine kinase; COG0642.	Sensory box/GGDEF family protein; COG2200.	0.604