(42 nodes) FAD/NAD(P)-binding domain superfamily network (Gloeobacter kilaueensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nadB	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa)
	GKIL_0087	Protoporphyrinogen oxidase; COG1233. (507 aa)
	GKIL_0148	FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1251. (535 aa)
	merA	Pyridine nucleotide-disulfide oxidoreductase; COG1249. (463 aa)
	ndh	NADH dehydrogenase; COG1252. (428 aa)
	merA-2	Mercuric reductase; COG1249. (502 aa)
	gltD	Geranylgeranyl reductase; COG0644. (375 aa)
	gltD-2	Protoporphyrinogen oxidase; COG1232. (448 aa)
	etf	Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (572 aa)
	trmFO	tRNA (uracil-5-)-methyltransferase Gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (449 aa)
	GKIL_0926	FAD-binding dehydrogenase; COG1233. (508 aa)
	thiO	Glycine oxidase ThiO; COG0665. (350 aa)
	ndh-2	NADH dehydrogenase; COG1252. (397 aa)
	lhgO	Hydroxyglutarate oxidase; COG0579. (407 aa)
	GKIL_1408	NADH dehydrogenase; COG1252. (400 aa)
	crtN	Phytoene dehydrogenase; COG1233. (546 aa)
	GKIL_1843	Mercuric reductase; COG1249. (448 aa)
	crtO	FAD dependent oxidoreductase; COG1233. (559 aa)
	trxB	Thioredoxin reductase; COG0492. (331 aa)
	GKIL_2388	Glucose-methanol-choline oxidoreductase; COG2303. (512 aa)
	gidA	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (627 aa)
	trxB-2	Thioredoxin reductase; COG0492. (318 aa)
	mhpA	Monooxygenase; COG0654. (487 aa)
	GKIL_2687	COG1249. (628 aa)
	crtU	Amine oxidase; COG3349. (657 aa)
	lpd	Dihydrolipoamide dehydrogenase; COG1249. (457 aa)
	sdhA	Succinate dehydrogenase flavoprotein subunit; COG1053. (576 aa)
	trxB-3	Thioredoxin reductase; COG0492. (555 aa)
	ndh-3	NADH dehydrogenase; COG1252. (417 aa)
	GKIL_3079	Protoporphyrinogen oxidase; COG1232. (491 aa)
	GKIL_3088	FAD dependent oxidoreductase; COG4529. (487 aa)
	ubiF	Geranylgeranyl reductase; COG0644. (374 aa)
	cruP	2-octaprenyl-6-methoxyphenyl hydroxylase; COG0644. (513 aa)
	chlP	Geranylgeranyl reductase; COG0644. (397 aa)
	GKIL_3479	FAD-binding monooxygenase, PheA/TfdB; COG0654. (530 aa)
	cruA	Lycopene cyclase; COG0644. (668 aa)
	trxB-4	Thioredoxin reductase; COG0492. (329 aa)
	hemY	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (469 aa)
	GKIL_0083	Protoporphyrinogen oxidase; COG3380. (343 aa)
	GKIL_3738	Protoporphyrinogen oxidase; COG1232. (485 aa)
	ndh-4	NADH dehydrogenase; COG1252. (420 aa)
	gltD-3	Glutamate synthase subunit beta; COG1233. (518 aa)

Your Current Organism:

Gloeobacter kilaueensis

NCBI taxonomy Id: 1183438
Other names: G. kilaueensis JS1, Gloeobacter kilaueensis JS1, Gloeobacter sp. JS

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GKIL_0087	crtN	GKIL_0087	GKIL_1835	Protoporphyrinogen oxidase; COG1233.	Phytoene dehydrogenase; COG1233.	0.747
GKIL_0148	merA	GKIL_0148	GKIL_0150	FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1251.	Pyridine nucleotide-disulfide oxidoreductase; COG1249.	0.468
GKIL_0148	trxB-3	GKIL_0148	GKIL_2947	FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1251.	Thioredoxin reductase; COG0492.	0.442
GKIL_0926	chlP	GKIL_0926	GKIL_3454	FAD-binding dehydrogenase; COG1233.	Geranylgeranyl reductase; COG0644.	0.591
GKIL_0926	cruP	GKIL_0926	GKIL_3349	FAD-binding dehydrogenase; COG1233.	2-octaprenyl-6-methoxyphenyl hydroxylase; COG0644.	0.401
GKIL_1843	GKIL_2687	GKIL_1843	GKIL_2687	Mercuric reductase; COG1249.	COG1249.	0.422
GKIL_1843	sdhA	GKIL_1843	GKIL_2914	Mercuric reductase; COG1249.	Succinate dehydrogenase flavoprotein subunit; COG1053.	0.422
GKIL_2687	GKIL_1843	GKIL_2687	GKIL_1843	COG1249.	Mercuric reductase; COG1249.	0.422
GKIL_2687	crtU	GKIL_2687	GKIL_2757	COG1249.	Amine oxidase; COG3349.	0.688
GKIL_2687	lpd	GKIL_2687	GKIL_2775	COG1249.	Dihydrolipoamide dehydrogenase; COG1249.	0.422
GKIL_2687	merA	GKIL_2687	GKIL_0150	COG1249.	Pyridine nucleotide-disulfide oxidoreductase; COG1249.	0.422
GKIL_2687	merA-2	GKIL_2687	GKIL_0238	COG1249.	Mercuric reductase; COG1249.	0.422
chlP	GKIL_0926	GKIL_3454	GKIL_0926	Geranylgeranyl reductase; COG0644.	FAD-binding dehydrogenase; COG1233.	0.591
chlP	crtN	GKIL_3454	GKIL_1835	Geranylgeranyl reductase; COG0644.	Phytoene dehydrogenase; COG1233.	0.517
chlP	etf	GKIL_3454	GKIL_0713	Geranylgeranyl reductase; COG0644.	Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.	0.630
crtN	GKIL_0087	GKIL_1835	GKIL_0087	Phytoene dehydrogenase; COG1233.	Protoporphyrinogen oxidase; COG1233.	0.747
crtN	chlP	GKIL_1835	GKIL_3454	Phytoene dehydrogenase; COG1233.	Geranylgeranyl reductase; COG0644.	0.517
crtN	cruA	GKIL_1835	GKIL_3517	Phytoene dehydrogenase; COG1233.	Lycopene cyclase; COG0644.	0.910
crtN	cruP	GKIL_1835	GKIL_3349	Phytoene dehydrogenase; COG1233.	2-octaprenyl-6-methoxyphenyl hydroxylase; COG0644.	0.910
crtO	crtU	GKIL_1997	GKIL_2757	FAD dependent oxidoreductase; COG1233.	Amine oxidase; COG3349.	0.926