50 items (Thermogladius calderae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	eno	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
	AFK50492.1	acetyl-CoA synthetase subunit alpha. (461 aa)
	rpiA	Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
	AFK50618.1	Glycosyl transferase group 1. (375 aa)
	AFK50687.1	Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
	AFK50688.1	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa)
	AFK50903.1	Metallophosphoesterase; Pfam00149, Metallophos, Calcineurin-like phosphoesterase. (232 aa)
	AFK51024.1	Aldehyde ferredoxin oxidoreductase. (608 aa)
	AFK51030.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN. (509 aa)
	AFK51031.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoBC. (332 aa)
	AFK51032.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoD; Belongs to the complex I 49 kDa subunit family. (365 aa)
	AFK51033.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI. (149 aa)
	AFK51041.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH. (323 aa)
	AFK51118.1	Tetrahydromethanopterin S-methyltransferase subunit H. (278 aa)
	AFK51136.1	CoA-binding domain protein. (458 aa)
	AFK51137.1	Phosphoesterase. (194 aa)
	AFK51145.1	PfkB domain protein. (325 aa)
	sucC	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
	sucD	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (265 aa)
	AFK51312.1	Ferredoxin. (81 aa)
	AFK51316.1	Membrane-bound hydrogenase, subunit NuoCD. (538 aa)
	AFK51317.1	Membrane-bound hydrogenase, subunit NuoI. (233 aa)
	AFK51318.1	Membrane-bound hydrogenase, subunit NuoH. (320 aa)
	AFK51321.1	Membrane-bound hydrogenase, subunit NuoL. (557 aa)
	AFK51322.1	Membrane-bound hydrogenase, subunit NuoN. (433 aa)
	AFK51382.1	Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. (650 aa)
	AFK51413.1	Na+/H+ antiporter, subunit D. (523 aa)
	AFK51414.1	Sulfide dehydrogenase subunit SudA. (367 aa)
	AFK51415.1	4Fe-4S ferredoxin, iron-sulfur binding domain protein. (165 aa)
	AFK51417.1	Na+/H+ antiporter, subunit D. (464 aa)
	AFK51418.1	Na+/H+ antiporter, subunit D. (505 aa)
	AFK51420.1	Membrane-bound hydrogenase, subunit NuoH. (289 aa)
	AFK51421.1	Membrane-bound hydrogenase, subunit NuoCD. (540 aa)
	AFK51422.1	Membrane-bound hydrogenase, subunit NuoI. (170 aa)
	rbsK	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (314 aa)
	AFK51476.1	[NiFe] hydrogenase, subunit alpha. (432 aa)
	AFK51519.1	Glycosyl transferase, group 1. (520 aa)
	AFK51530.1	Phosphoglycerate mutase. (426 aa)
	AFK51533.1	Beta-lactamase domain protein. (415 aa)
	AFK51541.1	Ferredoxin:NADP oxidoreductase, large subunit. (470 aa)
	AFK51656.1	2-oxoglutarate ferredoxin oxidoreductase subunit delta. (83 aa)
	AFK51688.1	Membrane-bound hydrogenase MBH, subunit NuoH. (327 aa)
	AFK51690.1	Na+/H+ antiporter, subunit MnhD. (525 aa)
	AFK51697.1	Membrane-bound hydrogenase MBH, subunit NuoI. (131 aa)
	AFK51699.1	Membrane-bound hydrogenase MBH, subunit NuoC. (138 aa)
	AFK51744.1	4Fe-4S ferredoxin, iron-sulfur binding domain protein. (162 aa)
	pgk	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
	gap	Glyceraldehyde-3-phosphate dehydrogenase. (340 aa)
	AFK51828.1	ATP-dependent phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
	AFK51829.1	Fructose-1,6-bisphosphate aldolase. (270 aa)

Your Current Organism:

Thermogladius calderae

NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFK50687.1	AFK50688.1	TCELL_0262	TCELL_0263	Pyruvate kinase; Belongs to the pyruvate kinase family.	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	0.804
AFK50687.1	AFK51829.1	TCELL_0262	TCELL_1407	Pyruvate kinase; Belongs to the pyruvate kinase family.	Fructose-1,6-bisphosphate aldolase.	0.863
AFK50687.1	eno	TCELL_0262	TCELL_0038	Pyruvate kinase; Belongs to the pyruvate kinase family.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.990
AFK50687.1	gap	TCELL_0262	TCELL_1375	Pyruvate kinase; Belongs to the pyruvate kinase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.816
AFK50687.1	pgk	TCELL_0262	TCELL_1374	Pyruvate kinase; Belongs to the pyruvate kinase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.867
AFK50688.1	AFK50687.1	TCELL_0263	TCELL_0262	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.804
AFK50688.1	AFK51031.1	TCELL_0263	TCELL_0606	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoBC.	0.793
AFK50688.1	AFK51032.1	TCELL_0263	TCELL_0607	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoD; Belongs to the complex I 49 kDa subunit family.	0.637
AFK50688.1	AFK51145.1	TCELL_0263	TCELL_0721	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	PfkB domain protein.	0.433
AFK50688.1	AFK51321.1	TCELL_0263	TCELL_0897	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Membrane-bound hydrogenase, subunit NuoL.	0.475
AFK50688.1	AFK51382.1	TCELL_0263	TCELL_0959	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase.	0.928
AFK50688.1	AFK51519.1	TCELL_0263	TCELL_1096	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Glycosyl transferase, group 1.	0.411
AFK50688.1	AFK51829.1	TCELL_0263	TCELL_1407	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Fructose-1,6-bisphosphate aldolase.	0.946
AFK50688.1	eno	TCELL_0263	TCELL_0038	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.974
AFK50688.1	gap	TCELL_0263	TCELL_1375	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.997
AFK50688.1	pgk	TCELL_0263	TCELL_1374	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.970
AFK50688.1	sucC	TCELL_0263	TCELL_0723	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.523
AFK50688.1	sucD	TCELL_0263	TCELL_0724	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.503
AFK51024.1	AFK51415.1	TCELL_0599	TCELL_0992	Aldehyde ferredoxin oxidoreductase.	4Fe-4S ferredoxin, iron-sulfur binding domain protein.	0.792
AFK51024.1	AFK51744.1	TCELL_0599	TCELL_1322	Aldehyde ferredoxin oxidoreductase.	4Fe-4S ferredoxin, iron-sulfur binding domain protein.	0.820