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| | AFK51226.1 | ATP-NAD/AcoX kinase. (370 aa) |
| | AFK51221.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (404 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (298 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (314 aa) |
| | AFK51205.1 | Aspartate kinase. (372 aa) |
| | AFK51192.1 | Molybdopterin binding domain protein. (246 aa) |
| | AFK51191.1 | Nicotinamide-nucleotide adenylyltransferase (NAD(+) pyrophosphorylase) (NAD(+) diphosphorylase) (NMN adenylyltransferase). (176 aa) |
| | AFK51180.1 | Dual specificity protein phosphatase. (286 aa) |
| | AFK51176.1 | Aspartate/glutamate/uridylate kinase. (259 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (176 aa) |
| | AFK51145.1 | PfkB domain protein. (325 aa) |
| | AFK51144.1 | Uridine phosphorylase. (276 aa) |
| | AFK51140.1 | Nicotinate phosphoribosyltransferase. (391 aa) |
| | AFK51139.1 | Hypothetical protein. (234 aa) |
| | nnrE | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (535 aa) |
| | AFK51120.1 | Hypothetical protein. (81 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | AFK51094.1 | Myo-inositol-1-phosphate synthase. (381 aa) |
| | AFK51088.1 | Indolepyruvate ferredoxin oxidoreductase subunit beta; Energy production and conversion; pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase. (209 aa) |
| | AFK51071.1 | triphosphoribosyl-dephospho-CoA protein. (314 aa) |
| | AFK51029.1 | Beta-lactamase domain protein. (287 aa) |
| | AFK51025.1 | Putative transcription regulator, containing Crp and DUF120 domains; Pfam01982, DUF120, Domain of unknown function DUF120. (124 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (239 aa) |
| | pyrD | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (306 aa) |
| | AFK51374.1 | Dihydroorotate dehydrogenase, electron transfer subunit. (247 aa) |
| | thiI | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (478 aa) |
| | AFK51404.1 | Hypothetical protein. (254 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (314 aa) |
| | AFK51436.1 | Thiamine biosynthesis protein ThiC. (447 aa) |
| | thi4 | Putative thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (259 aa) |
| | AFK51461.1 | Phosphoribosyltransferase. (215 aa) |
| | AFK51462.1 | Bifunctional GMP synthase/glutamine amidotransferase protein. (600 aa) |
| | AFK51474.1 | [NiFe] hydrogenase, gamma subunit. (275 aa) |
| | AFK51488.1 | Putative molybdenum utilization protein ModD; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (282 aa) |
| | pyrB | Aspartate carbamoyltransferase. (310 aa) |
| | AFK51492.1 | Orotidine-5'-phosphate decarboxylase. (224 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (197 aa) |
| | AFK51495.1 | Hypothetical protein. (85 aa) |
| | AFK51499.1 | Putative allantoinase. (444 aa) |
| | AFK51522.1 | Trehalose synthase-like protein. (466 aa) |
| | AFK51527.1 | Transcriptional regulator, Fis family. (292 aa) |
| | AFK51528.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | AFK51530.1 | Phosphoglycerate mutase. (426 aa) |
| | AFK51531.1 | Kinase (sugar kinase superfamily)-like protein. (302 aa) |
| | AFK51532.1 | DUF137 domain containing protein. (232 aa) |
| | AFK51539.1 | Indolepyruvate ferredoxin oxidoreductase subunit beta. (203 aa) |
| | AFK51540.1 | NTPase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (181 aa) |
| | AFK51542.1 | Ferredoxin:NADP oxidoreductase, small subunit. (269 aa) |
| | AFK51551.1 | V-type ATP synthase subunit D. (211 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa) |
| | atpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (591 aa) |
| | AFK51554.1 | V-type ATP synthase subunit F. (102 aa) |
| | AFK51556.1 | V-type ATP synthase subunit E. (197 aa) |
| | AFK51569.1 | Hypothetical protein. (270 aa) |
| | AFK51587.1 | Ribokinase. (321 aa) |
| | AFK51637.1 | Metal-dependent phosphohydrolase, HD region. (496 aa) |
| | AFK51650.1 | Type II secretion system protein E. (561 aa) |
| | AFK51653.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma. (179 aa) |
| | AFK51654.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (275 aa) |
| | AFK51657.1 | Pyruvate ferredoxinoxidoreductase subunit gamma. (186 aa) |
| | AFK51658.1 | Pyruvate ferredoxinoxidoreductase subunit delta. (90 aa) |
| | AFK51661.1 | Monooxygenase, FAD-binding protein. (357 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (222 aa) |
| | AFK51669.1 | Geranylgeranyl reductase. (455 aa) |
| | AFK51670.1 | AMP phosphorylase / thymidine phosphorylase. (509 aa) |
| | AFK51679.1 | Molybdenum cofactor synthesis domain protein. (405 aa) |
| | thiL | AIR synthase related protein domain protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (329 aa) |
| | AFK51686.1 | GHMP kinase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (311 aa) |
| | AFK51705.1 | HAD-superfamily hydrolase, subfamily IA, variant 1. (232 aa) |
| | AFK51706.1 | Molybdenum cofactor synthesis domain protein. (159 aa) |
| | AFK51709.1 | Beta-lactamase domain protein. (232 aa) |
| | AFK51729.1 | Phosphatases-like protein. (231 aa) |
| | moaA | Radical SAM domain protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (304 aa) |
| | AFK51748.1 | Molybdenum cofactor biosynthesis protein C. (147 aa) |
| | AFK51749.1 | Molybdopterin converting factor. (155 aa) |
| | AFK51750.1 | Hypothetical protein. (77 aa) |
| | AFK51752.1 | Cytidyltransferase-related domain protein. (175 aa) |
| | AFK51769.1 | Phosphoribosyltransferase. (215 aa) |
| | AFK51773.1 | hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family. (428 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (321 aa) |
| | AFK51791.1 | Carbamate kinase-like carbamoyl phosphate synthetase. (323 aa) |
| | AFK51795.1 | Dihydroorotate dehydrogenase family protein. (408 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase. (340 aa) |
| | AFK51828.1 | ATP-dependent phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | AFK51829.1 | Fructose-1,6-bisphosphate aldolase. (270 aa) |
| | AFK51019.1 | Putative adenylyl cyclase CyaB. (177 aa) |
| | AFK51014.1 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (162 aa) |
| | AFK51012.1 | NUDIX hydrolase. (184 aa) |
| | AFK51010.1 | Beta-lactamase domain protein. (235 aa) |
| | AFK50993.1 | ATP-NAD/AcoX kinase. (269 aa) |
| | AFK50980.1 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family. (193 aa) |
| | AFK50979.1 | Mn2+-dependent serine/threonine protein kinase. (227 aa) |
| | AFK50975.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (158 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa) |
| | AFK50936.1 | Nucleotide kinase-like protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (198 aa) |
| | AFK50932.1 | Thiamine S protein. (87 aa) |
| | AFK50922.1 | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. (223 aa) |
| | AFK50911.1 | Phosphoribosyltransferase. (223 aa) |
| | AFK50906.1 | Hypothetical protein. (295 aa) |
| | AFK50893.1 | Geranylgeranylglycerol- phosphategeranylgeranyltransferase. (287 aa) |
| | AFK50889.1 | SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (242 aa) |
| | AFK50858.1 | ATP-cone domain protein. (87 aa) |
| | AFK50856.1 | Molybdopterin biosynthesis protein. (345 aa) |
| | AFK50821.1 | Non-specific serine/threonine protein kinase. (260 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (305 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (175 aa) |
| | rbcL | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa) |
| | cmk | Cytidylate kinase. (187 aa) |
| | AFK50738.1 | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (246 aa) |
| | AFK50737.1 | MazG nucleotide pyrophosphohydrolase. (85 aa) |
| | AFK50733.1 | Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit delta. (91 aa) |
| | AFK50732.1 | Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma. (190 aa) |
| | AFK50721.1 | Type II secretion system protein E. (496 aa) |
| | AFK50688.1 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa) |
| | AFK50687.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa) |
| | AFK50661.1 | Adenine phosphoribosyltransferase. (288 aa) |
| | AFK50657.1 | Histidine triad (HIT) protein. (159 aa) |
| | AFK50643.1 | Nicotinamide-nucleotide adenylyltransferase. (175 aa) |
| | egsA | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (352 aa) |
| | AFK50600.1 | Thymidylate kinase-like protein. (202 aa) |
| | AFK50560.1 | Phosphoribosyltransferase. (174 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (532 aa) |
| | AFK50554.1 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (166 aa) |
| | tmk | Thymidylate kinase. (205 aa) |
| | AFK50533.1 | Protein kinase. (530 aa) |
| | AFK50529.1 | Fructose-1,6-bisphosphatase. (260 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa) |
| | AFK50516.1 | Metal dependent phosphohydrolase. (189 aa) |
| | AFK50501.1 | dephospho-CoA kinase, CoaE; Belongs to the UPF0200 family. (191 aa) |
| | AFK50498.1 | Ser/Thr protein kinase-like protein. (253 aa) |
| | AFK50495.1 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (286 aa) |
| | AFK50482.1 | Putative nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (183 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa) |
| | AFK50448.1 | RIO-like serine/threonine kinase. (292 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (281 aa) |
| | AFK51324.1 | Hypothetical protein. (453 aa) |
| | AFK51323.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (838 aa) |
| | AFK51305.1 | Amidohydrolase. (449 aa) |
| | AFK51279.1 | Hexokinase; Galactose metabolism Glycolysis / Gluconeogenesis Starch and sucrose metabolism Streptomycin biosynthesis; pfam00480, ROK, ROK family. (318 aa) |
| | AFK51262.1 | Flavoprotein. (242 aa) |
| | mptD | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (127 aa) |
| | AFK51250.1 | DUF198 domain containing protein. (262 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (236 aa) |
| | AFK51239.1 | Metal dependent phosphohydrolase. (537 aa) |
| | AFK51231.1 | ParB domain protein nuclease. (239 aa) |
