(25 nodes) Cellular respiration network (Thermogladius calderae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFK50492.1	acetyl-CoA synthetase subunit alpha. (461 aa)
	AFK50903.1	Metallophosphoesterase; Pfam00149, Metallophos, Calcineurin-like phosphoesterase. (232 aa)
	AFK51030.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN. (509 aa)
	AFK51033.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI. (149 aa)
	AFK51041.1	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH. (323 aa)
	AFK51118.1	Tetrahydromethanopterin S-methyltransferase subunit H. (278 aa)
	AFK51136.1	CoA-binding domain protein. (458 aa)
	AFK51137.1	Phosphoesterase. (194 aa)
	sucC	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
	sucD	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (265 aa)
	AFK51317.1	Membrane-bound hydrogenase, subunit NuoI. (233 aa)
	AFK51318.1	Membrane-bound hydrogenase, subunit NuoH. (320 aa)
	AFK51321.1	Membrane-bound hydrogenase, subunit NuoL. (557 aa)
	AFK51322.1	Membrane-bound hydrogenase, subunit NuoN. (433 aa)
	AFK51413.1	Na+/H+ antiporter, subunit D. (523 aa)
	AFK51414.1	Sulfide dehydrogenase subunit SudA. (367 aa)
	AFK51415.1	4Fe-4S ferredoxin, iron-sulfur binding domain protein. (165 aa)
	AFK51417.1	Na+/H+ antiporter, subunit D. (464 aa)
	AFK51418.1	Na+/H+ antiporter, subunit D. (505 aa)
	AFK51422.1	Membrane-bound hydrogenase, subunit NuoI. (170 aa)
	AFK51476.1	[NiFe] hydrogenase, subunit alpha. (432 aa)
	AFK51541.1	Ferredoxin:NADP oxidoreductase, large subunit. (470 aa)
	AFK51688.1	Membrane-bound hydrogenase MBH, subunit NuoH. (327 aa)
	AFK51690.1	Na+/H+ antiporter, subunit MnhD. (525 aa)
	AFK51697.1	Membrane-bound hydrogenase MBH, subunit NuoI. (131 aa)

Your Current Organism:

Thermogladius calderae

NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFK51030.1	AFK51033.1	TCELL_0605	TCELL_0608	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	0.926
AFK51030.1	AFK51041.1	TCELL_0605	TCELL_0616	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH.	0.862
AFK51030.1	AFK51317.1	TCELL_0605	TCELL_0893	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound hydrogenase, subunit NuoI.	0.602
AFK51030.1	AFK51321.1	TCELL_0605	TCELL_0897	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound hydrogenase, subunit NuoL.	0.921
AFK51030.1	AFK51422.1	TCELL_0605	TCELL_0999	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound hydrogenase, subunit NuoI.	0.602
AFK51030.1	AFK51697.1	TCELL_0605	TCELL_1274	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	Membrane-bound hydrogenase MBH, subunit NuoI.	0.602
AFK51033.1	AFK51030.1	TCELL_0608	TCELL_0605	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	0.926
AFK51033.1	AFK51041.1	TCELL_0608	TCELL_0616	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH.	0.986
AFK51033.1	AFK51318.1	TCELL_0608	TCELL_0894	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound hydrogenase, subunit NuoH.	0.944
AFK51033.1	AFK51321.1	TCELL_0608	TCELL_0897	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound hydrogenase, subunit NuoL.	0.922
AFK51033.1	AFK51322.1	TCELL_0608	TCELL_0898	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound hydrogenase, subunit NuoN.	0.602
AFK51033.1	AFK51413.1	TCELL_0608	TCELL_0990	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Na+/H+ antiporter, subunit D.	0.602
AFK51033.1	AFK51417.1	TCELL_0608	TCELL_0994	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Na+/H+ antiporter, subunit D.	0.602
AFK51033.1	AFK51418.1	TCELL_0608	TCELL_0995	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Na+/H+ antiporter, subunit D.	0.602
AFK51033.1	AFK51688.1	TCELL_0608	TCELL_1265	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Membrane-bound hydrogenase MBH, subunit NuoH.	0.920
AFK51033.1	AFK51690.1	TCELL_0608	TCELL_1267	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	Na+/H+ antiporter, subunit MnhD.	0.673
AFK51033.1	sucD	TCELL_0608	TCELL_0724	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.454
AFK51041.1	AFK51030.1	TCELL_0616	TCELL_0605	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoN.	0.862
AFK51041.1	AFK51033.1	TCELL_0616	TCELL_0608	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH.	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoI.	0.986
AFK51041.1	AFK51317.1	TCELL_0616	TCELL_0893	Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoH.	Membrane-bound hydrogenase, subunit NuoI.	0.920