STRINGSTRING
AFK51531.1 AFK51531.1 AFK51829.1 AFK51829.1 AFK51828.1 AFK51828.1 gap gap pgk pgk AFK51795.1 AFK51795.1 AFK51785.1 AFK51785.1 mvk mvk AFK51773.1 AFK51773.1 AFK51769.1 AFK51769.1 AFK51741.1 AFK51741.1 AFK51705.1 AFK51705.1 AFK51670.1 AFK51670.1 upp upp AFK51658.1 AFK51658.1 AFK51657.1 AFK51657.1 AFK51654.1 AFK51654.1 AFK51653.1 AFK51653.1 AFK51637.1 AFK51637.1 AFK51597.1 AFK51597.1 AFK51590.1 AFK51590.1 AFK51556.1 AFK51556.1 AFK51554.1 AFK51554.1 atpA atpA atpB atpB AFK51551.1 AFK51551.1 AFK51539.1 AFK51539.1 AFK51532.1 AFK51532.1 AFK51530.1 AFK51530.1 panB panB AFK51528.1 AFK51528.1 AFK51499.1 AFK51499.1 pyrE pyrE AFK51492.1 AFK51492.1 pyrB pyrB AFK51462.1 AFK51462.1 AFK51461.1 AFK51461.1 rbsK rbsK AFK51404.1 AFK51404.1 pyrD pyrD deoC deoC AFK51324.1 AFK51324.1 AFK51305.1 AFK51305.1 AFK51279.1 AFK51279.1 AFK51241.1 AFK51241.1 AFK51239.1 AFK51239.1 gcvPA gcvPA AFK51221.1 AFK51221.1 prs prs AFK51145.1 AFK51145.1 AFK51144.1 AFK51144.1 taw3 taw3 adk adk AFK51088.1 AFK51088.1 AFK51067.1 AFK51067.1 AFK51025.1 AFK51025.1 AFK51019.1 AFK51019.1 AFK51012.1 AFK51012.1 AFK50975.1 AFK50975.1 ndk ndk AFK50924.1 AFK50924.1 glmS glmS AFK50922.1 AFK50922.1 AFK50911.1 AFK50911.1 mtnP mtnP AFK50894.1 AFK50894.1 AFK50886.1 AFK50886.1 AFK50826.1 AFK50826.1 thyX thyX dcd dcd rbcL rbcL AFK50733.1 AFK50733.1 AFK50732.1 AFK50732.1 AFK50688.1 AFK50688.1 AFK50687.1 AFK50687.1 AFK50661.1 AFK50661.1 AFK50657.1 AFK50657.1 AFK50607.1 AFK50607.1 AFK50606.1 AFK50606.1 AFK50604.1 AFK50604.1 AFK50603.1 AFK50603.1 AFK50602.1 AFK50602.1 AFK50601.1 AFK50601.1 AFK50600.1 AFK50600.1 AFK50560.1 AFK50560.1 pyrG pyrG tmk tmk rpiA rpiA AFK50495.1 AFK50495.1 eno eno
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFK51531.1Kinase (sugar kinase superfamily)-like protein. (302 aa)
AFK51829.1Fructose-1,6-bisphosphate aldolase. (270 aa)
AFK51828.1ATP-dependent phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (340 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
AFK51795.1Dihydroorotate dehydrogenase family protein. (408 aa)
AFK51785.1Oligosaccharyl transferase, STT3 subunit. (818 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (321 aa)
AFK51773.1hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family. (428 aa)
AFK51769.1Phosphoribosyltransferase. (215 aa)
AFK51741.1Purine and other phosphorylase, family 1. (243 aa)
AFK51705.1HAD-superfamily hydrolase, subfamily IA, variant 1. (232 aa)
AFK51670.1AMP phosphorylase / thymidine phosphorylase. (509 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (222 aa)
AFK51658.1Pyruvate ferredoxinoxidoreductase subunit delta. (90 aa)
AFK51657.1Pyruvate ferredoxinoxidoreductase subunit gamma. (186 aa)
AFK51654.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (275 aa)
AFK51653.12-oxoglutarate ferredoxin oxidoreductase subunit gamma. (179 aa)
AFK51637.1Metal-dependent phosphohydrolase, HD region. (496 aa)
AFK51597.1NUDIX hydrolase. (149 aa)
AFK51590.15'-methylthioadenosine phosphorylase (mtaP). (243 aa)
AFK51556.1V-type ATP synthase subunit E. (197 aa)
AFK51554.1V-type ATP synthase subunit F. (102 aa)
atpAV-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (591 aa)
atpBV-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa)
AFK51551.1V-type ATP synthase subunit D. (211 aa)
AFK51539.1Indolepyruvate ferredoxin oxidoreductase subunit beta. (203 aa)
AFK51532.1DUF137 domain containing protein. (232 aa)
AFK51530.1Phosphoglycerate mutase. (426 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa)
AFK51528.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa)
AFK51499.1Putative allantoinase. (444 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (197 aa)
AFK51492.1Orotidine-5'-phosphate decarboxylase. (224 aa)
pyrBAspartate carbamoyltransferase. (310 aa)
AFK51462.1Bifunctional GMP synthase/glutamine amidotransferase protein. (600 aa)
AFK51461.1Phosphoribosyltransferase. (215 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (314 aa)
AFK51404.1Hypothetical protein. (254 aa)
pyrDDihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (306 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (239 aa)
AFK51324.1Hypothetical protein. (453 aa)
AFK51305.1Amidohydrolase. (449 aa)
AFK51279.1Hexokinase; Galactose metabolism Glycolysis / Gluconeogenesis Starch and sucrose metabolism Streptomycin biosynthesis; pfam00480, ROK, ROK family. (318 aa)
AFK51241.1Cytidine deaminase. (129 aa)
AFK51239.1Metal dependent phosphohydrolase. (537 aa)
gcvPAGlycine dehydrogenase subunit alpha; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (455 aa)
AFK51221.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (404 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (298 aa)
AFK51145.1PfkB domain protein. (325 aa)
AFK51144.1Uridine phosphorylase. (276 aa)
taw3Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (247 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa)
AFK51088.1Indolepyruvate ferredoxin oxidoreductase subunit beta; Energy production and conversion; pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase. (209 aa)
AFK51067.13-hexulose-6-phosphate isomerase. (192 aa)
AFK51025.1Putative transcription regulator, containing Crp and DUF120 domains; Pfam01982, DUF120, Domain of unknown function DUF120. (124 aa)
AFK51019.1Putative adenylyl cyclase CyaB. (177 aa)
AFK51012.1NUDIX hydrolase. (184 aa)
AFK50975.1Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (158 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa)
AFK50924.1Nucleotidyl transferase. (394 aa)
glmSD-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)
AFK50922.1Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. (223 aa)
AFK50911.1Phosphoribosyltransferase. (223 aa)
mtnP5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (273 aa)
AFK50894.1Glucose-6-phosphate isomerase; Carbohydrate transport and metabolism. (332 aa)
AFK50886.1Hypothetical protein. (661 aa)
AFK50826.1Nucleotidyl transferase. (424 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (305 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (175 aa)
rbcLRibulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa)
AFK50733.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit delta. (91 aa)
AFK50732.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma. (190 aa)
AFK50688.1Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa)
AFK50687.1Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
AFK50661.1Adenine phosphoribosyltransferase. (288 aa)
AFK50657.1Histidine triad (HIT) protein. (159 aa)
AFK50607.1Glycosyl transferase family 2. (82 aa)
AFK50606.1Glycosyl transferase family 2. (205 aa)
AFK50604.1dTDP-glucose 4,6-dehydratase. (333 aa)
AFK50603.1dTDP-4-dehydrorhamnose reductase. (298 aa)
AFK50602.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa)
AFK50601.1Glycosyl transferase, family 2. (362 aa)
AFK50600.1Thymidylate kinase-like protein. (202 aa)
AFK50560.1Phosphoribosyltransferase. (174 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (532 aa)
tmkThymidylate kinase. (205 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
AFK50495.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (286 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
Your Current Organism:
Thermogladius calderae
NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633
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