STRINGSTRING
nadE nadE mat mat AFK50449.1 AFK50449.1 AFK50455.1 AFK50455.1 eno eno gatE gatE gatD gatD AFK50482.1 AFK50482.1 AFK50491.1 AFK50491.1 AFK50495.1 AFK50495.1 rpiA rpiA ade ade AFK50525.1 AFK50525.1 AFK50529.1 AFK50529.1 AFK50538.1 AFK50538.1 tmk tmk pyrG pyrG AFK50569.1 AFK50569.1 ubiX ubiX AFK50596.1 AFK50596.1 AFK50598.1 AFK50598.1 AFK50602.1 AFK50602.1 AFK50603.1 AFK50603.1 AFK50604.1 AFK50604.1 AFK50605.1 AFK50605.1 AFK50630.1 AFK50630.1 AFK50643.1 AFK50643.1 AFK50657.1 AFK50657.1 AFK50661.1 AFK50661.1 AFK50687.1 AFK50687.1 AFK50688.1 AFK50688.1 fbp fbp ahcY ahcY AFK50698.1 AFK50698.1 AFK50732.1 AFK50732.1 AFK50733.1 AFK50733.1 AFK50734.1 AFK50734.1 AFK50735.1 AFK50735.1 AFK50742.1 AFK50742.1 cmk cmk AFK50785.1 AFK50785.1 rbcL rbcL dcd dcd thyX thyX AFK50797.1 AFK50797.1 AFK50826.1 AFK50826.1 AFK50854.1 AFK50854.1 AFK50860.1 AFK50860.1 AFK50889.1 AFK50889.1 AFK50894.1 AFK50894.1 mtnP mtnP AFK50922.1 AFK50922.1 glmS glmS AFK50924.1 AFK50924.1 AFK50936.1 AFK50936.1 fni fni gltX gltX ndk ndk AFK50975.1 AFK50975.1 AFK50980.1 AFK50980.1 AFK50983.1 AFK50983.1 AFK50993.1 AFK50993.1 AFK51011.1 AFK51011.1 AFK51012.1 AFK51012.1 AFK51019.1 AFK51019.1 AFK51024.1 AFK51024.1 AFK51025.1 AFK51025.1 AFK51032.1 AFK51032.1 AFK51060.1 AFK51060.1 AFK51061.1 AFK51061.1 AFK51063.1 AFK51063.1 ade-2 ade-2 AFK51067.1 AFK51067.1 AFK51076.1 AFK51076.1 AFK51094.1 AFK51094.1 adk adk AFK51115.1 AFK51115.1 AFK51118.1 AFK51118.1 AFK51136.1 AFK51136.1 AFK51140.1 AFK51140.1 AFK51144.1 AFK51144.1 AFK51145.1 AFK51145.1 sucC sucC sucD sucD AFK51158.1 AFK51158.1 AFK51164.1 AFK51164.1 AFK51165.1 AFK51165.1 AFK51168.1 AFK51168.1 AFK51176.1 AFK51176.1 AFK51191.1 AFK51191.1 AFK51198.1 AFK51198.1 leuC leuC leuD leuD AFK51201.1 AFK51201.1 AFK51202.1 AFK51202.1 AFK51203.1 AFK51203.1 AFK51204.1 AFK51204.1 AFK51205.1 AFK51205.1 AFK51206.1 AFK51206.1 thrB thrB prs prs AFK51221.1 AFK51221.1 AFK51223.1 AFK51223.1 gcvH gcvH glyA glyA AFK51227.1 AFK51227.1 gcvPA gcvPA AFK51229.1 AFK51229.1 AFK51230.1 AFK51230.1 AFK51231.1 AFK51231.1 AFK51241.1 AFK51241.1 AFK51250.1 AFK51250.1 AFK51266.1 AFK51266.1 AFK51271.1 AFK51271.1 AFK51272.1 AFK51272.1 AFK51279.1 AFK51279.1 AFK51280.1 AFK51280.1 AFK51295.1 AFK51295.1 AFK51296.1 AFK51296.1 AFK51303.1 AFK51303.1 AFK51305.1 AFK51305.1 AFK51313.1 AFK51313.1 AFK51314.1 AFK51314.1 AFK51320.1 AFK51320.1 AFK51321.1 AFK51321.1 AFK51322.1 AFK51322.1 AFK51323.1 AFK51323.1 AFK51337.1 AFK51337.1 AFK51338.1 AFK51338.1 AFK51347.1 AFK51347.1 speE speE deoC deoC AFK51356.1 AFK51356.1 AFK51357.1 AFK51357.1 AFK51358.1 AFK51358.1 AFK51363.1 AFK51363.1 AFK51366.1 AFK51366.1 AFK51367.1 AFK51367.1 pyrD pyrD AFK51374.1 AFK51374.1 AFK51380.1 AFK51380.1 AFK51382.1 AFK51382.1 thiI thiI AFK51414.1 AFK51414.1 rbsK rbsK AFK51436.1 AFK51436.1 thi4 thi4 AFK51447.1 AFK51447.1 AFK51457.1 AFK51457.1 AFK51462.1 AFK51462.1 hisD hisD pyrB pyrB AFK51492.1 AFK51492.1 pyrE pyrE AFK51499.1 AFK51499.1 AFK51500.1 AFK51500.1 pckG pckG AFK51519.1 AFK51519.1 AFK51520.1 AFK51520.1 AFK51521.1 AFK51521.1 AFK51522.1 AFK51522.1 AFK51528.1 AFK51528.1 panB panB AFK51530.1 AFK51530.1 AFK51531.1 AFK51531.1 AFK51532.1 AFK51532.1 AFK51540.1 AFK51540.1 AFK51541.1 AFK51541.1 AFK51542.1 AFK51542.1 AFK51551.1 AFK51551.1 atpB atpB atpA atpA AFK51556.1 AFK51556.1 AFK51557.1 AFK51557.1 AFK51558.1 AFK51558.1 AFK51559.1 AFK51559.1 AFK51580.1 AFK51580.1 AFK51583.1 AFK51583.1 AFK51587.1 AFK51587.1 AFK51590.1 AFK51590.1 AFK51594.1 AFK51594.1 proC proC AFK51613.1 AFK51613.1 AFK51615.1 AFK51615.1 AFK51653.1 AFK51653.1 AFK51654.1 AFK51654.1 AFK51655.1 AFK51655.1 AFK51656.1 AFK51656.1 AFK51657.1 AFK51657.1 AFK51658.1 AFK51658.1 AFK51659.1 AFK51659.1 AFK51660.1 AFK51660.1 speH speH AFK51663.1 AFK51663.1 upp upp trpB trpB AFK51679.1 AFK51679.1 thiL thiL AFK51688.1 AFK51688.1 AFK51697.1 AFK51697.1 AFK51706.1 AFK51706.1 AFK51708.1 AFK51708.1 AFK51718.1 AFK51718.1 AFK51729.1 AFK51729.1 AFK51735.1 AFK51735.1 AFK51741.1 AFK51741.1 AFK51743.1 AFK51743.1 AFK51746.1 AFK51746.1 moaA moaA AFK51748.1 AFK51748.1 AFK51749.1 AFK51749.1 AFK51752.1 AFK51752.1 AFK51754.1 AFK51754.1 AFK51758.1 AFK51758.1 AFK51759.1 AFK51759.1 AFK51764.1 AFK51764.1 AFK51766.1 AFK51766.1 AFK51768.1 AFK51768.1 AFK51769.1 AFK51769.1 AFK51775.1 AFK51775.1 mvk mvk AFK51785.1 AFK51785.1 argF argF AFK51788.1 AFK51788.1 AFK51791.1 AFK51791.1 AFK51793.1 AFK51793.1 AFK51795.1 AFK51795.1 pgk pgk gap gap AFK51799.1 AFK51799.1 AFK51800.1 AFK51800.1 AFK51828.1 AFK51828.1 AFK51829.1 AFK51829.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (281 aa)
matMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (413 aa)
AFK50449.1Pyridoxal-dependent decarboxylase. (384 aa)
AFK50455.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. (458 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (643 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (450 aa)
AFK50482.1Putative nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (183 aa)
AFK50491.1acetyl-CoA synthetase subunit beta. (237 aa)
AFK50495.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (286 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
adeAdenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (589 aa)
AFK50525.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (309 aa)
AFK50529.1Fructose-1,6-bisphosphatase. (260 aa)
AFK50538.1Sugar-phosphate isomerase, RpiB/LacA/LacB family. (155 aa)
tmkThymidylate kinase. (205 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (532 aa)
AFK50569.1Agmatinase; Belongs to the arginase family. (285 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (201 aa)
AFK50596.1Cysteine synthase. (394 aa)
AFK50598.1NAD-dependent epimerase/dehydratase. (322 aa)
AFK50602.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa)
AFK50603.1dTDP-4-dehydrorhamnose reductase. (298 aa)
AFK50604.1dTDP-glucose 4,6-dehydratase. (333 aa)
AFK50605.1Glucose-1-phosphate thymidylyltransferase. (354 aa)
AFK50630.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (360 aa)
AFK50643.1Nicotinamide-nucleotide adenylyltransferase. (175 aa)
AFK50657.1Histidine triad (HIT) protein. (159 aa)
AFK50661.1Adenine phosphoribosyltransferase. (288 aa)
AFK50687.1Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
AFK50688.1Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (384 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (419 aa)
AFK50698.1DNA-cytosine methyltransferase. (322 aa)
AFK50732.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma. (190 aa)
AFK50733.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit delta. (91 aa)
AFK50734.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit alpha. (398 aa)
AFK50735.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit beta. (297 aa)
AFK50742.1Phosphoadenosine phosphosulfate reductase. (662 aa)
cmkCytidylate kinase. (187 aa)
AFK50785.1Nucleotidyl transferase. (258 aa)
rbcLRibulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (175 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (305 aa)
AFK50797.1Anaerobic ribonucleoside triphosphate reductase. (636 aa)
AFK50826.1Nucleotidyl transferase. (424 aa)
AFK50854.1Glycosyl transferase, family 39. (481 aa)
AFK50860.12-amino-3-ketobutyrate coenzyme A ligase. (399 aa)
AFK50889.1SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (242 aa)
AFK50894.1Glucose-6-phosphate isomerase; Carbohydrate transport and metabolism. (332 aa)
mtnP5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (273 aa)
AFK50922.1Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. (223 aa)
glmSD-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)
AFK50924.1Nucleotidyl transferase. (394 aa)
AFK50936.1Nucleotide kinase-like protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (198 aa)
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (355 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (579 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa)
AFK50975.1Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (158 aa)
AFK50980.1Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family. (193 aa)
AFK50983.1Pullulanase. (673 aa)
AFK50993.1ATP-NAD/AcoX kinase. (269 aa)
AFK51011.1Class II aldolase/adducin family protein. (200 aa)
AFK51012.1NUDIX hydrolase. (184 aa)
AFK51019.1Putative adenylyl cyclase CyaB. (177 aa)
AFK51024.1Aldehyde ferredoxin oxidoreductase. (608 aa)
AFK51025.1Putative transcription regulator, containing Crp and DUF120 domains; Pfam01982, DUF120, Domain of unknown function DUF120. (124 aa)
AFK51032.1Membrane-bound ferredoxin-NADPH oxidoreductase MBX, subunit NuoD; Belongs to the complex I 49 kDa subunit family. (365 aa)
AFK51060.1Glycosyltransferase 28, C-terminal domain protein. (350 aa)
AFK51061.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (443 aa)
AFK51063.1Amidohydrolase. (473 aa)
ade-2Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (618 aa)
AFK51067.13-hexulose-6-phosphate isomerase. (192 aa)
AFK51076.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (335 aa)
AFK51094.1Myo-inositol-1-phosphate synthase. (381 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa)
AFK51115.1Methionine synthase II (cobalamin-independent)-like protein. (317 aa)
AFK51118.1Tetrahydromethanopterin S-methyltransferase subunit H. (278 aa)
AFK51136.1CoA-binding domain protein. (458 aa)
AFK51140.1Nicotinate phosphoribosyltransferase. (391 aa)
AFK51144.1Uridine phosphorylase. (276 aa)
AFK51145.1PfkB domain protein. (325 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (265 aa)
AFK51158.1Hypothetical protein. (174 aa)
AFK51164.1Orotidine 5'-phosphate decarboxylase. (204 aa)
AFK51165.1Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (359 aa)
AFK51168.1Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (425 aa)
AFK51176.1Aspartate/glutamate/uridylate kinase. (259 aa)
AFK51191.1Nicotinamide-nucleotide adenylyltransferase (NAD(+) pyrophosphorylase) (NAD(+) diphosphorylase) (NMN adenylyltransferase). (176 aa)
AFK51198.1Pyruvate carboxyltransferase. (427 aa)
leuC3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (404 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (171 aa)
AFK51201.1Isocitrate dehydrogenase. (341 aa)
AFK51202.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (346 aa)
AFK51203.1Cystathionine gamma-synthase. (386 aa)
AFK51204.1Aspartate-semialdehyde dehydrogenase. (354 aa)
AFK51205.1Aspartate kinase. (372 aa)
AFK51206.1Homoserine dehydrogenase. (339 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (314 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (298 aa)
AFK51221.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (404 aa)
AFK51223.1Aminotransferase. (405 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (146 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
AFK51227.1Glycine cleavage system aminomethyltransferase T. (371 aa)
gcvPAGlycine dehydrogenase subunit alpha; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (455 aa)
AFK51229.1Glycine dehydrogenase subunit beta. (519 aa)
AFK51230.1Dihydrolipoamide dehydrogenase. (456 aa)
AFK51231.1ParB domain protein nuclease. (239 aa)
AFK51241.1Cytidine deaminase. (129 aa)
AFK51250.1DUF198 domain containing protein. (262 aa)
AFK51266.1Nucleotidyl transferase. (836 aa)
AFK51271.1Glycerol-3-phosphate cytidylyltransferase. (234 aa)
AFK51272.1Orn/DAP/Arg decarboxylase 2. (595 aa)
AFK51279.1Hexokinase; Galactose metabolism Glycolysis / Gluconeogenesis Starch and sucrose metabolism Streptomycin biosynthesis; pfam00480, ROK, ROK family. (318 aa)
AFK51280.1methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (513 aa)
AFK51295.1Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase. (507 aa)
AFK51296.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (425 aa)
AFK51303.1Family 2 glycosyltransferase. (231 aa)
AFK51305.1Amidohydrolase. (449 aa)
AFK51313.1Succinyl-diaminopimelate desuccinylase. (378 aa)
AFK51314.1Carbamoyl-phosphate synthase L chain, ATP-binding protein. (505 aa)
AFK51320.1Na+/H+ antiporter, subunit MnhC. (94 aa)
AFK51321.1Membrane-bound hydrogenase, subunit NuoL. (557 aa)
AFK51322.1Membrane-bound hydrogenase, subunit NuoN. (433 aa)
AFK51323.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (838 aa)
AFK51337.1Peptidase T2, asparaginase 2. (318 aa)
AFK51338.15-formyltetrahydrofolate cyclo-ligase. (248 aa)
AFK51347.1HD superfamily metal-dependent phosphohydrolase. (237 aa)
speESpermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (290 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (239 aa)
AFK51356.1Biotin/lipoyl attachment domain-containing protein. (171 aa)
AFK51357.1Carboxyl transferase. (520 aa)
AFK51358.1Thiolase. (391 aa)
AFK51363.1Dihydropteroate synthase. (290 aa)
AFK51366.1Nucleotidyl transferase. (373 aa)
AFK51367.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (409 aa)
pyrDDihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (306 aa)
AFK51374.1Dihydroorotate dehydrogenase, electron transfer subunit. (247 aa)
AFK51380.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
AFK51382.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. (650 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (478 aa)
AFK51414.1Sulfide dehydrogenase subunit SudA. (367 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (314 aa)
AFK51436.1Thiamine biosynthesis protein ThiC. (447 aa)
thi4Putative thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (259 aa)
AFK51447.1Phosphomethylpyrimidine kinase. (451 aa)
AFK51457.1Aldo/keto reductase. (332 aa)
AFK51462.1Bifunctional GMP synthase/glutamine amidotransferase protein. (600 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa)
pyrBAspartate carbamoyltransferase. (310 aa)
AFK51492.1Orotidine-5'-phosphate decarboxylase. (224 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (197 aa)
AFK51499.1Putative allantoinase. (444 aa)
AFK51500.1Aminotransferase, class I and II. (399 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (633 aa)
AFK51519.1Glycosyl transferase, group 1. (520 aa)
AFK51520.1Glycoside hydrolase, family 57. (640 aa)
AFK51521.1Glycoside hydrolase, family 57. (513 aa)
AFK51522.1Trehalose synthase-like protein. (466 aa)
AFK51528.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa)
AFK51530.1Phosphoglycerate mutase. (426 aa)
AFK51531.1Kinase (sugar kinase superfamily)-like protein. (302 aa)
AFK51532.1DUF137 domain containing protein. (232 aa)
AFK51540.1NTPase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (181 aa)
AFK51541.1Ferredoxin:NADP oxidoreductase, large subunit. (470 aa)
AFK51542.1Ferredoxin:NADP oxidoreductase, small subunit. (269 aa)
AFK51551.1V-type ATP synthase subunit D. (211 aa)
atpBV-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa)
atpAV-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (591 aa)
AFK51556.1V-type ATP synthase subunit E. (197 aa)
AFK51557.1V-type ATP synthase subunit c. (168 aa)
AFK51558.1V-type ATP synthase subunit a. (661 aa)
AFK51559.1Hypothetical protein. (102 aa)
AFK51580.1Putative transcriptional regulator, GntR family. (404 aa)
AFK51583.1hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (352 aa)
AFK51587.1Ribokinase. (321 aa)
AFK51590.15'-methylthioadenosine phosphorylase (mtaP). (243 aa)
AFK51594.1N-ethylammeline chlorohydrolase. (438 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
AFK51613.1Pyruvate carboxylase subunit B. (463 aa)
AFK51615.1Plasma-membrane proton-efflux P-type ATPase. (777 aa)
AFK51653.12-oxoglutarate ferredoxin oxidoreductase subunit gamma. (179 aa)
AFK51654.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (275 aa)
AFK51655.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (374 aa)
AFK51656.12-oxoglutarate ferredoxin oxidoreductase subunit delta. (83 aa)
AFK51657.1Pyruvate ferredoxinoxidoreductase subunit gamma. (186 aa)
AFK51658.1Pyruvate ferredoxinoxidoreductase subunit delta. (90 aa)
AFK51659.1Pyruvate ferredoxinoxidoreductase subunit alpha. (422 aa)
AFK51660.1Pyruvate ferredoxin oxidoreductase subunit beta. (355 aa)
speHS-adenosylmethionine decarboxylase related protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (127 aa)
AFK51663.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. (476 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (222 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (437 aa)
AFK51679.1Molybdenum cofactor synthesis domain protein. (405 aa)
thiLAIR synthase related protein domain protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (329 aa)
AFK51688.1Membrane-bound hydrogenase MBH, subunit NuoH. (327 aa)
AFK51697.1Membrane-bound hydrogenase MBH, subunit NuoI. (131 aa)
AFK51706.1Molybdenum cofactor synthesis domain protein. (159 aa)
AFK51708.1Alpha amylase. (693 aa)
AFK51718.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
AFK51729.1Phosphatases-like protein. (231 aa)
AFK51735.1Phosphoserine phosphatase. (221 aa)
AFK51741.1Purine and other phosphorylase, family 1. (243 aa)
AFK51743.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (484 aa)
AFK51746.1FAD dependent oxidoreductase. (379 aa)
moaARadical SAM domain protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (304 aa)
AFK51748.1Molybdenum cofactor biosynthesis protein C. (147 aa)
AFK51749.1Molybdopterin converting factor. (155 aa)
AFK51752.1Cytidyltransferase-related domain protein. (175 aa)
AFK51754.1biotin--acetyl-CoA-carboxylase ligase. (302 aa)
AFK51758.1Lipoate-protein ligase A. (99 aa)
AFK51759.1Lipoate protein ligase related protein. (265 aa)
AFK51764.1Threonine synthase. (433 aa)
AFK51766.1Glutamine synthetase, type I. (432 aa)
AFK51768.1Glycosyl transferase, family 4. (342 aa)
AFK51769.1Phosphoribosyltransferase. (215 aa)
AFK51775.1Molybdenum cofactor synthesis domain protein. (657 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (321 aa)
AFK51785.1Oligosaccharyl transferase, STT3 subunit. (818 aa)
argFOrnithine carbamoyltransferase. (314 aa)
AFK51788.1Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (361 aa)
AFK51791.1Carbamate kinase-like carbamoyl phosphate synthetase. (323 aa)
AFK51793.1Amidohydrolase. (460 aa)
AFK51795.1Dihydroorotate dehydrogenase family protein. (408 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (340 aa)
AFK51799.16-phosphogluconate dehydrogenase, NAD-binding protein. (286 aa)
AFK51800.1Glycosyl transferase, group 1. (507 aa)
AFK51828.1ATP-dependent phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
AFK51829.1Fructose-1,6-bisphosphate aldolase. (270 aa)
Your Current Organism:
Thermogladius calderae
NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633
Server load: low (22%) [HD]