STRINGSTRING
AFK50455.1 AFK50455.1 eno eno AFK50491.1 AFK50491.1 AFK50495.1 AFK50495.1 rpiA rpiA AFK50525.1 AFK50525.1 AFK50538.1 AFK50538.1 ubiX ubiX AFK50596.1 AFK50596.1 AFK50630.1 AFK50630.1 AFK50687.1 AFK50687.1 AFK50688.1 AFK50688.1 fbp fbp AFK50732.1 AFK50732.1 AFK50733.1 AFK50733.1 AFK50735.1 AFK50735.1 AFK50742.1 AFK50742.1 rbcL rbcL AFK50894.1 AFK50894.1 gltX gltX AFK51011.1 AFK51011.1 AFK51024.1 AFK51024.1 AFK51067.1 AFK51067.1 AFK51076.1 AFK51076.1 AFK51118.1 AFK51118.1 AFK51136.1 AFK51136.1 sucC sucC sucD sucD AFK51164.1 AFK51164.1 AFK51168.1 AFK51168.1 AFK51198.1 AFK51198.1 AFK51201.1 AFK51201.1 AFK51202.1 AFK51202.1 AFK51204.1 AFK51204.1 AFK51205.1 AFK51205.1 AFK51206.1 AFK51206.1 thrB thrB prs prs glyA glyA AFK51230.1 AFK51230.1 AFK51279.1 AFK51279.1 AFK51295.1 AFK51295.1 AFK51296.1 AFK51296.1 AFK51313.1 AFK51313.1 AFK51314.1 AFK51314.1 AFK51323.1 AFK51323.1 AFK51356.1 AFK51356.1 AFK51357.1 AFK51357.1 AFK51358.1 AFK51358.1 AFK51367.1 AFK51367.1 AFK51380.1 AFK51380.1 AFK51382.1 AFK51382.1 AFK51414.1 AFK51414.1 AFK51457.1 AFK51457.1 AFK51499.1 AFK51499.1 pckG pckG AFK51530.1 AFK51530.1 AFK51541.1 AFK51541.1 AFK51613.1 AFK51613.1 AFK51653.1 AFK51653.1 AFK51654.1 AFK51654.1 AFK51655.1 AFK51655.1 AFK51656.1 AFK51656.1 AFK51657.1 AFK51657.1 AFK51658.1 AFK51658.1 AFK51659.1 AFK51659.1 AFK51660.1 AFK51660.1 AFK51718.1 AFK51718.1 AFK51735.1 AFK51735.1 AFK51764.1 AFK51764.1 AFK51766.1 AFK51766.1 AFK51791.1 AFK51791.1 pgk pgk gap gap AFK51829.1 AFK51829.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFK50455.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. (458 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
AFK50491.1acetyl-CoA synthetase subunit beta. (237 aa)
AFK50495.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (286 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
AFK50525.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (309 aa)
AFK50538.1Sugar-phosphate isomerase, RpiB/LacA/LacB family. (155 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (201 aa)
AFK50596.1Cysteine synthase. (394 aa)
AFK50630.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (360 aa)
AFK50687.1Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
AFK50688.1Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (384 aa)
AFK50732.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma. (190 aa)
AFK50733.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit delta. (91 aa)
AFK50735.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit beta. (297 aa)
AFK50742.1Phosphoadenosine phosphosulfate reductase. (662 aa)
rbcLRibulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa)
AFK50894.1Glucose-6-phosphate isomerase; Carbohydrate transport and metabolism. (332 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (579 aa)
AFK51011.1Class II aldolase/adducin family protein. (200 aa)
AFK51024.1Aldehyde ferredoxin oxidoreductase. (608 aa)
AFK51067.13-hexulose-6-phosphate isomerase. (192 aa)
AFK51076.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (335 aa)
AFK51118.1Tetrahydromethanopterin S-methyltransferase subunit H. (278 aa)
AFK51136.1CoA-binding domain protein. (458 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (265 aa)
AFK51164.1Orotidine 5'-phosphate decarboxylase. (204 aa)
AFK51168.1Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (425 aa)
AFK51198.1Pyruvate carboxyltransferase. (427 aa)
AFK51201.1Isocitrate dehydrogenase. (341 aa)
AFK51202.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (346 aa)
AFK51204.1Aspartate-semialdehyde dehydrogenase. (354 aa)
AFK51205.1Aspartate kinase. (372 aa)
AFK51206.1Homoserine dehydrogenase. (339 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (314 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (298 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
AFK51230.1Dihydrolipoamide dehydrogenase. (456 aa)
AFK51279.1Hexokinase; Galactose metabolism Glycolysis / Gluconeogenesis Starch and sucrose metabolism Streptomycin biosynthesis; pfam00480, ROK, ROK family. (318 aa)
AFK51295.1Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase. (507 aa)
AFK51296.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (425 aa)
AFK51313.1Succinyl-diaminopimelate desuccinylase. (378 aa)
AFK51314.1Carbamoyl-phosphate synthase L chain, ATP-binding protein. (505 aa)
AFK51323.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (838 aa)
AFK51356.1Biotin/lipoyl attachment domain-containing protein. (171 aa)
AFK51357.1Carboxyl transferase. (520 aa)
AFK51358.1Thiolase. (391 aa)
AFK51367.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (409 aa)
AFK51380.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
AFK51382.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. (650 aa)
AFK51414.1Sulfide dehydrogenase subunit SudA. (367 aa)
AFK51457.1Aldo/keto reductase. (332 aa)
AFK51499.1Putative allantoinase. (444 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (633 aa)
AFK51530.1Phosphoglycerate mutase. (426 aa)
AFK51541.1Ferredoxin:NADP oxidoreductase, large subunit. (470 aa)
AFK51613.1Pyruvate carboxylase subunit B. (463 aa)
AFK51653.12-oxoglutarate ferredoxin oxidoreductase subunit gamma. (179 aa)
AFK51654.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (275 aa)
AFK51655.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (374 aa)
AFK51656.12-oxoglutarate ferredoxin oxidoreductase subunit delta. (83 aa)
AFK51657.1Pyruvate ferredoxinoxidoreductase subunit gamma. (186 aa)
AFK51658.1Pyruvate ferredoxinoxidoreductase subunit delta. (90 aa)
AFK51659.1Pyruvate ferredoxinoxidoreductase subunit alpha. (422 aa)
AFK51660.1Pyruvate ferredoxin oxidoreductase subunit beta. (355 aa)
AFK51718.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
AFK51735.1Phosphoserine phosphatase. (221 aa)
AFK51764.1Threonine synthase. (433 aa)
AFK51766.1Glutamine synthetase, type I. (432 aa)
AFK51791.1Carbamate kinase-like carbamoyl phosphate synthetase. (323 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (340 aa)
AFK51829.1Fructose-1,6-bisphosphate aldolase. (270 aa)
Your Current Organism:
Thermogladius calderae
NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633
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