STRINGSTRING
eno eno AFK50495.1 AFK50495.1 rpiA rpiA AFK50525.1 AFK50525.1 AFK50538.1 AFK50538.1 AFK50687.1 AFK50687.1 AFK50688.1 AFK50688.1 fbp fbp AFK50732.1 AFK50732.1 AFK50733.1 AFK50733.1 AFK50735.1 AFK50735.1 rbcL rbcL AFK50894.1 AFK50894.1 AFK51024.1 AFK51024.1 AFK51067.1 AFK51067.1 AFK51076.1 AFK51076.1 AFK51118.1 AFK51118.1 sucC sucC sucD sucD AFK51164.1 AFK51164.1 AFK51168.1 AFK51168.1 AFK51198.1 AFK51198.1 AFK51201.1 AFK51201.1 prs prs gcvH gcvH glyA glyA AFK51227.1 AFK51227.1 gcvPA gcvPA AFK51229.1 AFK51229.1 AFK51230.1 AFK51230.1 AFK51279.1 AFK51279.1 AFK51295.1 AFK51295.1 AFK51314.1 AFK51314.1 AFK51323.1 AFK51323.1 AFK51356.1 AFK51356.1 AFK51357.1 AFK51357.1 AFK51358.1 AFK51358.1 AFK51382.1 AFK51382.1 AFK51530.1 AFK51530.1 AFK51613.1 AFK51613.1 AFK51653.1 AFK51653.1 AFK51654.1 AFK51654.1 AFK51655.1 AFK51655.1 AFK51656.1 AFK51656.1 AFK51657.1 AFK51657.1 AFK51658.1 AFK51658.1 AFK51659.1 AFK51659.1 AFK51660.1 AFK51660.1 AFK51735.1 AFK51735.1 AFK51791.1 AFK51791.1 pgk pgk gap gap AFK51829.1 AFK51829.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
AFK50495.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (286 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
AFK50525.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (309 aa)
AFK50538.1Sugar-phosphate isomerase, RpiB/LacA/LacB family. (155 aa)
AFK50687.1Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
AFK50688.1Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (203 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (384 aa)
AFK50732.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma. (190 aa)
AFK50733.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit delta. (91 aa)
AFK50735.1Pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit beta. (297 aa)
rbcLRibulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa)
AFK50894.1Glucose-6-phosphate isomerase; Carbohydrate transport and metabolism. (332 aa)
AFK51024.1Aldehyde ferredoxin oxidoreductase. (608 aa)
AFK51067.13-hexulose-6-phosphate isomerase. (192 aa)
AFK51076.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (335 aa)
AFK51118.1Tetrahydromethanopterin S-methyltransferase subunit H. (278 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (265 aa)
AFK51164.1Orotidine 5'-phosphate decarboxylase. (204 aa)
AFK51168.1Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (425 aa)
AFK51198.1Pyruvate carboxyltransferase. (427 aa)
AFK51201.1Isocitrate dehydrogenase. (341 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (298 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (146 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
AFK51227.1Glycine cleavage system aminomethyltransferase T. (371 aa)
gcvPAGlycine dehydrogenase subunit alpha; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (455 aa)
AFK51229.1Glycine dehydrogenase subunit beta. (519 aa)
AFK51230.1Dihydrolipoamide dehydrogenase. (456 aa)
AFK51279.1Hexokinase; Galactose metabolism Glycolysis / Gluconeogenesis Starch and sucrose metabolism Streptomycin biosynthesis; pfam00480, ROK, ROK family. (318 aa)
AFK51295.1Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase. (507 aa)
AFK51314.1Carbamoyl-phosphate synthase L chain, ATP-binding protein. (505 aa)
AFK51323.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (838 aa)
AFK51356.1Biotin/lipoyl attachment domain-containing protein. (171 aa)
AFK51357.1Carboxyl transferase. (520 aa)
AFK51358.1Thiolase. (391 aa)
AFK51382.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. (650 aa)
AFK51530.1Phosphoglycerate mutase. (426 aa)
AFK51613.1Pyruvate carboxylase subunit B. (463 aa)
AFK51653.12-oxoglutarate ferredoxin oxidoreductase subunit gamma. (179 aa)
AFK51654.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (275 aa)
AFK51655.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (374 aa)
AFK51656.12-oxoglutarate ferredoxin oxidoreductase subunit delta. (83 aa)
AFK51657.1Pyruvate ferredoxinoxidoreductase subunit gamma. (186 aa)
AFK51658.1Pyruvate ferredoxinoxidoreductase subunit delta. (90 aa)
AFK51659.1Pyruvate ferredoxinoxidoreductase subunit alpha. (422 aa)
AFK51660.1Pyruvate ferredoxin oxidoreductase subunit beta. (355 aa)
AFK51735.1Phosphoserine phosphatase. (221 aa)
AFK51791.1Carbamate kinase-like carbamoyl phosphate synthetase. (323 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (340 aa)
AFK51829.1Fructose-1,6-bisphosphate aldolase. (270 aa)
Your Current Organism:
Thermogladius calderae
NCBI taxonomy Id: 1184251
Other names: T. calderae 1633, Thermogladius calderae 1633
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