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A11Q_1003 A11Q_1003 A11Q_1880 A11Q_1880 kdsB kdsB A11Q_723 A11Q_723 A11Q_724 A11Q_724 A11Q_782 A11Q_782 A11Q_918 A11Q_918 A11Q_920 A11Q_920 lpxK lpxK A11Q_922 A11Q_922 lpxC lpxC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A11Q_1003Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (408 aa)
A11Q_1880Hypothetical protein; Belongs to the KdsA family. (284 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (240 aa)
A11Q_723Polysialic acid capsule expression protein; COG0794M; Belongs to the SIS family. GutQ/KpsF subfamily. (325 aa)
A11Q_724Hypothetical protein; COG1778R. (167 aa)
A11Q_782UDP glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (333 aa)
A11Q_918UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (269 aa)
A11Q_920Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa)
A11Q_922Lipid A biosynthesis lauroyl acyltransferase; COG1560M. (290 aa)
lpxCUDP-3-O-acyl-N-acetylglucosamine deacetylase lpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (300 aa)
Your Current Organism:
Bdellovibrio exovorus
NCBI taxonomy Id: 1184267
Other names: B. exovorus JSS, Bdellovibrio exovorus JSS, Bdellovibrio exovorus str. JSS, Bdellovibrio exovorus strain JSS, Bdellovibrio sp. JSS
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