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A11Q_1021 A11Q_1021 A11Q_1230 A11Q_1230 glyA glyA A11Q_1634 A11Q_1634 A11Q_1710 A11Q_1710 gpmA gpmA A11Q_1843 A11Q_1843 pfkA pfkA mdh mdh eno eno A11Q_786 A11Q_786
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A11Q_1021Fructose-bisphosphate aldolase; COG1830G. (308 aa)
A11Q_1230Hypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (785 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
A11Q_1634Acetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (646 aa)
A11Q_1710Phosphoglycerate dehydrogenase; COG0111HE; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)
A11Q_1843D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (402 aa)
pfkAHypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
mdhHypothetical protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (314 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
A11Q_786Hypothetical protein; Belongs to the phosphoglycerate mutase family. (203 aa)
Your Current Organism:
Bdellovibrio exovorus
NCBI taxonomy Id: 1184267
Other names: B. exovorus JSS, Bdellovibrio exovorus JSS, Bdellovibrio exovorus str. JSS, Bdellovibrio exovorus strain JSS, Bdellovibrio sp. JSS
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