STRINGSTRING
AFL48770.1 AFL48770.1 dadA1 dadA1 aroC aroC hisC1 hisC1 dadA3 dadA3 AFL50721.1 AFL50721.1 melA1 melA1 pheC pheC vllY vllY aroE1 aroE1 AFL50809.1 AFL50809.1 aatB1 aatB1 aroQ1 aroQ1 dat dat dapA4 dapA4 trpC trpC trpD trpD aroH aroH aatA aatA AFL53253.1 AFL53253.1 tyrC tyrC hisC2 hisC2 aroB aroB aroK aroK yjbG yjbG pabB pabB AFL53791.1 AFL53791.1 cyaB cyaB dadA5 dadA5 maiA maiA AFL53935.1 AFL53935.1 hmgA hmgA AFL53937.1 AFL53937.1 hpd hpd aroQ2 aroQ2 aroE2 aroE2 hisC3 hisC3 pheAa pheAa aatB2 aatB2 aroE3 aroE3 trpF trpF trpB trpB trpA trpA pheA pheA aroA aroA tatA2 tatA2 yhhY yhhY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFL48770.1Hypothetical protein. (101 aa)
dadA1D-amino acid dehydrogenase small subunit DadA; Oxidative deamination of D-amino acids. (415 aa)
aroCChorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
hisC1Histidinol-phosphate aminotransferase. (373 aa)
dadA3D-amino acid dehydrogenase small subunit DadA; Oxidative deamination of D-amino acids. (416 aa)
AFL50721.1Shikimate 5-dehydrogenase. (277 aa)
melA1Protein MelA. (629 aa)
pheCCyclohexadienyl dehydratase PheC. (256 aa)
vllYHemolysin VllY. (629 aa)
aroE1Shikimate dehydrogenase AroE. (291 aa)
AFL50809.1Transcriptional regulator, TetR/ArcR family. (255 aa)
aatB1Aspartate aminotransferase B. (403 aa)
aroQ13-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
datD-alanine aminotransferase Dat. (287 aa)
dapA4Dihydrodipicolinate synthase DapA; Belongs to the DapA family. (296 aa)
trpCIndole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. (271 aa)
trpDAnthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
aroHPhospho-2-dehydro-3-deoxyheptonate aldolase AroH. (457 aa)
aatAAspartate aminotransferase A. (456 aa)
AFL53253.1trpE(G): anthranilate synthase. (729 aa)
tyrCProtein TyrC. (308 aa)
hisC2Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
aroB3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa)
aroKShikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa)
yjbGOligoendopeptidase F. (673 aa)
pabBPara-aminobenzoate synthase component 1. (385 aa)
AFL53791.1Putative aminotransferase, class IV. (208 aa)
cyaBAdenylate cyclase 2. (1086 aa)
dadA5D-amino acid dehydrogenase small subunit DadA. (411 aa)
maiAMaleylacetoacetate isomerase MaiA. (213 aa)
AFL53935.1Fumarylacetoacetate hydrolase family protein. (338 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa)
AFL53937.1Putative transcriptional regulator, MarR family. (149 aa)
hpd4-hydroxyphenylpyruvate dioxygenase Hpd. (372 aa)
aroQ23-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
aroE2Shikimate dehydrogenase AroE; Belongs to the shikimate dehydrogenase family. (286 aa)
hisC3Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa)
pheAaPutative chorismate mutase. (112 aa)
aatB2Aspartate aminotransferase B. (410 aa)
aroE3Shikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (224 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
pheAP-protein PheA. (316 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (448 aa)
tatA2Tyrosine aminotransferase TatA. (389 aa)
yhhYPutative N-acetyltransferase YhhY. (167 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
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