STRINGSTRING
aroC aroC AFL50721.1 AFL50721.1 aroE1 aroE1 aroQ1 aroQ1 trpC trpC trpD trpD aroH aroH usg usg AFL53005.1 AFL53005.1 AFL53253.1 AFL53253.1 tyrC tyrC aroB aroB aroK aroK maiA maiA hmgA hmgA hpd hpd aroQ2 aroQ2 aroE2 aroE2 aroE3 aroE3 trpF trpF trpB trpB trpA trpA pheA pheA aroA aroA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroCChorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
AFL50721.1Shikimate 5-dehydrogenase. (277 aa)
aroE1Shikimate dehydrogenase AroE. (291 aa)
aroQ13-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
trpCIndole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. (271 aa)
trpDAnthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
aroHPhospho-2-dehydro-3-deoxyheptonate aldolase AroH. (457 aa)
usgProtein Usg. (88 aa)
AFL53005.1Putative transmembrane protein. (270 aa)
AFL53253.1trpE(G): anthranilate synthase. (729 aa)
tyrCProtein TyrC. (308 aa)
aroB3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa)
aroKShikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa)
maiAMaleylacetoacetate isomerase MaiA. (213 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa)
hpd4-hydroxyphenylpyruvate dioxygenase Hpd. (372 aa)
aroQ23-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
aroE2Shikimate dehydrogenase AroE; Belongs to the shikimate dehydrogenase family. (286 aa)
aroE3Shikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (224 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
pheAP-protein PheA. (316 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (448 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
Server load: low (10%) [HD]