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| | cysK | O-acetylserine sulfhydrylase CysK. (322 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit HisZ; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (379 aa) |
| | puuA | Gamma-glutamylputrescine synthetase PuuA; Belongs to the glutamine synthetase family. (478 aa) |
| | folD1 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. (131 aa) |
| | AFL48827.1 | Hypothetical protein. (301 aa) |
| | AFL48824.1 | Putative membrane protein. (474 aa) |
| | ttuC | Putative tartrate dehydrogenase/decarboxylase ttuC. (357 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) |
| | AFL48788.1 | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. (471 aa) |
| | AFL48770.1 | Hypothetical protein. (101 aa) |
| | argF1 | Ornithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa) |
| | argD1 | Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | putA | Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1311 aa) |
| | argB | Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa) |
| | dapD-2 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (285 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (398 aa) |
| | AFL49129.1 | Gluconolactonase. (294 aa) |
| | AFL49202.1 | Putative acetyltransferase. (170 aa) |
| | fabI1 | Enoyl-[acyl-carrier-protein] reductase [NADH]. (272 aa) |
| | aroC | Chorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa) |
| | thrB | Homoserine kinase ThrB; Belongs to the pseudomonas-type ThrB family. (326 aa) |
| | thrC | Threonine synthase ThrC. (465 aa) |
| | AFL49258.1 | Hypothetical protein. (98 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase CysH; Reduction of activated sulfate into sulfite. (251 aa) |
| | mas | Mycocerosic acid synthase Mas. (335 aa) |
| | dkgB | 2,5-diketo-D-gluconic acid reductase B. (276 aa) |
| | ilvE1 | Putative branched-chain-amino-acid aminotransferase IlvE. (293 aa) |
| | AFL49306.1 | Homocysteine S-methyltransferase. (322 aa) |
| | hisC1 | Histidinol-phosphate aminotransferase. (373 aa) |
| | dapA1 | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (139 aa) |
| | rkpK | UDP-glucose 6-dehydrogenase RkpK. (437 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (359 aa) |
| | AFL49432.1 | Putative AIPM/hcit synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (538 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase FabD. (329 aa) |
| | acpP | Acyl carrier protein AcpP; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | fabF1 | 3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa) |
| | glyA | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | plsX | Phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (359 aa) |
| | fabH1 | 3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (323 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (150 aa) |
| | hyuE1 | Hydantoin racemase HyuE. (245 aa) |
| | fabI2 | Enoyl-[acyl-carrier-protein] reductase [NADH]. (261 aa) |
| | AFL49737.1 | Hypothetical protein. (63 aa) |
| | panB1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB. (273 aa) |
| | AFL49856.1 | Putative DAPA-like lyase; Belongs to the DapA family. (331 aa) |
| | serA1 | D-3-phosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa) |
| | AFL49936.1 | Hypothetical protein. (387 aa) |
| | AFL50056.1 | Hypothetical protein. (87 aa) |
| | asnB1 | Asparagine synthetase; Glutamine-hydrolyzing. (665 aa) |
| | AFL50078.1 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit. (991 aa) |
| | AFL50081.1 | NADP-dependent oxidoreductase domain protein. (305 aa) |
| | ygbL | Putative aldolase class 2 protein YgbL. (225 aa) |
| | gln | Glutamine synthetase. (344 aa) |
| | pccB | propionyl-CoA carboxylase beta chain. (510 aa) |
| | AFL50268.1 | Hypothetical protein. (480 aa) |
| | serA2 | D-3-phosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa) |
| | AFL50336.1 | methylmalonyl-CoA carboxyltransferase 12S subunit. (512 aa) |
| | folD2 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa) |
| | lipA2 | Lipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) |
| | fabF2 | 3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (434 aa) |
| | AFL50623.1 | Putative NADPH:quinone reductase. (315 aa) |
| | AFL50628.1 | Hypothetical protein. (234 aa) |
| | AFL50721.1 | Shikimate 5-dehydrogenase. (277 aa) |
| | melA1 | Protein MelA. (629 aa) |
| | AFL50802.1 | Bifunctional deaminase-reductase domain protein. (176 aa) |
| | vllY | Hemolysin VllY. (629 aa) |
| | aroE1 | Shikimate dehydrogenase AroE. (291 aa) |
| | mCD | Putative MCD, malonyl-CoA decarboxylase MCD. (473 aa) |
| | AFL50979.1 | Uncharacterized protein y4xO. (379 aa) |
| | AFL50980.1 | Putative cysteine synthase. (336 aa) |
| | AFL50981.1 | Uncharacterized protein y4yA. (457 aa) |
| | amaB1 | N-carbamoyl-L-amino acid hydrolase AmaB. (421 aa) |
| | gnl1 | Gluconolactonase Gnl. (304 aa) |
| | gnl2 | Gluconolactonase Gnl. (298 aa) |
| | AFL51091.1 | Hypothetical protein; Belongs to the DapA family. (319 aa) |
| | yvrE | Uncharacterized protein YvrE. (292 aa) |
| | proC1 | Pyrroline-5-carboxylate reductase ProC. (255 aa) |
| | proC2 | Pyrroline-5-carboxylate reductase protein ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | AFL51212.1 | Homocysteine S-methyltransferase (S-methylmethionine). (311 aa) |
| | AFL51354.1 | Dihydrodipicolinate synthase; Belongs to the DapA family. (297 aa) |
| | AFL51362.1 | Hypothetical protein; Belongs to the DapA family. (311 aa) |
| | AFL51417.1 | Hypothetical protein. (115 aa) |
| | AFL51420.1 | Hypothetical protein. (345 aa) |
| | bioF1 | 8-amino-7-oxononanoate synthase BioF. (420 aa) |
| | AFL51560.1 | Putative aminotransferase y4uB; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (494 aa) |
| | ycsA | Putative tartrate dehydrogenase/decarboxylase. (349 aa) |
| | argE | Acetylornithine deacetylase ArgE. (375 aa) |
| | pqqB | Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (303 aa) |
| | pqqC | Pyrroloquinoline-quinone synthase PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (256 aa) |
| | pqqD | Coenzyme PQQ synthesis protein D. (98 aa) |
| | pqqE | Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (376 aa) |
| | yogA1 | Putative zinc-type alcohol dehydrogenase-like protein YogA. (357 aa) |
| | AFL51695.1 | Putative aminotransferase y4uB; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | fucA | L-fuculose phosphate aldolase FucA. (234 aa) |
| | yngE | Putative carboxylase YngE. (535 aa) |
| | asnB2 | Asparagine synthetase [glutamine-hydrolyzing] 1. (653 aa) |
| | AFL51762.1 | Hypothetical protein. (330 aa) |
| | AFL51808.1 | Metal dependent beta lactamase protein. (276 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (310 aa) |
| | mdeA3 | Methionine gamma-lyase MdeA. (427 aa) |
| | AFL51849.1 | Hypothetical protein. (395 aa) |
| | accC | Biotin carboxylase AccC; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | accB | Biotin carboxyl carrier protein of acetyl-CoA carboxylase AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | aroQ1 | 3-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase HisI; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (150 aa) |
| | AFL52026.1 | IAA acetyltransferase. (156 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Belongs to the KdsA family. (280 aa) |
| | lipA3 | Lipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (323 aa) |
| | sir2 | Sulfite reductase [ferredoxin] 2. (557 aa) |
| | cysE | Serine acetyltransferase CysE. (275 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa) |
| | serS | serine--tRNA ligase SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | hom | Homoserine dehydrogenase Hom. (440 aa) |
| | trpC | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. (271 aa) |
| | trpD | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa) |
| | glnA1 | Glutamine synthetase 1. (469 aa) |
| | cbs | Putative cystathionine beta-synthase. (346 aa) |
| | serA3 | D-3-phosphoglycerate dehydrogenase SerA. (336 aa) |
| | nosD | Copper-binding periplasmic protein. (441 aa) |
| | argF2 | Ornithine carbamoyltransferase ArgF. (341 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1166 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (190 aa) |
| | folB | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa) |
| | sul | Dihydropteroate synthase Sul; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (304 aa) |
| | aroH | Phospho-2-dehydro-3-deoxyheptonate aldolase AroH. (457 aa) |
| | gph | Phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (227 aa) |
| | usg | Protein Usg. (88 aa) |
| | fabF3 | 3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (427 aa) |
| | AFL52758.1 | 3-oxoacyl-(acyl-carrier-protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (399 aa) |
| | AFL52759.1 | Hydroxymyristoyl-acyl carrier protein dehydratase. (158 aa) |
| | acpXL | Acyl carrier protein AcpXL. (92 aa) |
| | metH2 | Methionine synthase MetH. (320 aa) |
| | AFL52802.1 | Hypothetical protein. (690 aa) |
| | AFL52816.1 | Putative pyrimidine reductase protein. (219 aa) |
| | ilvC | Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | ilvH | Putative acetolactate synthase small subunit IlvH. (190 aa) |
| | AFL52976.1 | Phosphoserine phosphatase. (337 aa) |
| | AFL52983.1 | dhfrIII: dihydrofolate reductase type 3; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (179 aa) |
| | hyuE2 | Hydantoin racemase HyuE. (251 aa) |
| | panB2 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | panC | Pantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (291 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (310 aa) |
| | glnA2 | Glutamine synthetase GlnA. (454 aa) |
| | kbl | 2-amino-3-ketobutyrate coenzyme A ligase Kbl; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (401 aa) |
| | proC3 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | leuA | 2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (569 aa) |
| | AFL53253.1 | trpE(G): anthranilate synthase. (729 aa) |
| | AFL53270.1 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa) |
| | AFL53324.1 | Hypothetical protein. (362 aa) |
| | preT | NAD-dependent dihydropyrimidine dehydrogenase subunit PreT. (453 aa) |
| | amaB2 | N-carbamoyl-L-amino acid hydrolase AmaB. (416 aa) |
| | fabH2 | 3-oxoacyl-[acyl-carrier-protein] synthase 3. (329 aa) |
| | bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa) |
| | bioD | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (212 aa) |
| | bioF2 | Putative 8-amino-7-oxononanoate synthase BioF. (380 aa) |
| | bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (339 aa) |
| | lysC | Aspartokinase LysC; Belongs to the aspartokinase family. (424 aa) |
| | yyaP | Uncharacterized protein YyaP. (181 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa) |
| | argH | Argininosuccinate lyase ArgH. (467 aa) |
| | lysA | Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | tyrC | Protein TyrC. (308 aa) |
| | hisC2 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa) |
| | aroB | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa) |
| | aroK | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | AFL53639.1 | Uncharacterized protein. (329 aa) |
| | serA4 | D-3-phosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | serC | Phosphoserine aminotransferase SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa) |
| | gltB1 | Glutamate synthase [NADPH] small chain. (485 aa) |
| | gltB2 | Ferredoxin-dependent glutamate synthase 1. (1574 aa) |
| | ilvD4 | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (612 aa) |
| | cobG | precorrin-3B synthase CobG. (439 aa) |
| | metH3 | Methionine synthase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1256 aa) |
| | hemA1 | 5-aminolevulinate synthase HemA. (404 aa) |
| | rocD | Ornithine aminotransferase RocD; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (401 aa) |
| | AFL54110.1 | Putative uroporphyrinogen-III synthase protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (236 aa) |
| | aroQ2 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | aroE2 | Shikimate dehydrogenase AroE; Belongs to the shikimate dehydrogenase family. (286 aa) |
| | hemA2 | 5-aminolevulinate synthase HemA. (429 aa) |
| | proB | Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (393 aa) |
| | proA | Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (434 aa) |
| | metA | Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | hisC3 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa) |
| | argG | Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa) |
| | dapF | Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (300 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | AFL54318.1 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa) |
| | AFL54333.1 | Hypothetical protein. (390 aa) |
| | leuB | 3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (381 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | ectC | L-ectoine synthase EctC; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (128 aa) |
| | aroE3 | Shikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (224 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (304 aa) |
| | folC | Folylpolyglutamate synthase FolC; Belongs to the folylpolyglutamate synthase family. (447 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase HisE. (107 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HisA. (245 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase HisB. (202 aa) |
| | punA | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (265 aa) |
| | dapB | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (272 aa) |
| | AFL54537.1 | Putative membrane protein. (247 aa) |
| | ilvE3 | Putative branched-chain-amino-acid aminotransferase IlvE. (364 aa) |
| | pheA | P-protein PheA. (316 aa) |
| | fabI3 | Enoyl-[acyl-carrier-protein] reductase [NADH]. (268 aa) |
| | fabB | 3-oxoacyl-[acyl-carrier-protein] synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa) |
| | fabA | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (448 aa) |
| | AFL54603.1 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (313 aa) |
