STRINGSTRING
arcB1 arcB1 coaBC coaBC AFL54617.1 AFL54617.1 slyX slyX murQ murQ AFL54393.1 AFL54393.1 yjjN yjjN garD garD hpcH hpcH gdhB gdhB AFL54275.1 AFL54275.1 AFL54155.1 AFL54155.1 hmgA hmgA AFL53935.1 AFL53935.1 dadA5 dadA5 AFL53879.1 AFL53879.1 AFL53878.1 AFL53878.1 soxB soxB soxG soxG AFL53812.1 AFL53812.1 ltaE ltaE AFL53742.1 AFL53742.1 hutH2 hutH2 paaA paaA paaB paaB paaC paaC paaD paaD AFL53537.1 AFL53537.1 maoC maoC paaK2 paaK2 paaI paaI fadB1 fadB1 AFL53295.1 AFL53295.1 tdh4 tdh4 AFL53086.1 AFL53086.1 AFL53048.1 AFL53048.1 AFL53005.1 AFL53005.1 AFL52724.1 AFL52724.1 tdh3 tdh3 gcvT3 gcvT3 gcvH gcvH gcvP gcvP anmK anmK ald ald ilvA ilvA AFL51910.1 AFL51910.1 AFL51801.1 AFL51801.1 AFL51742.1 AFL51742.1 mvaB mvaB AFL51714.1 AFL51714.1 ocd1 ocd1 AFL51705.1 AFL51705.1 AFL51601.1 AFL51601.1 AFL51577.1 AFL51577.1 AFL51533.1 AFL51533.1 AFL51232.1 AFL51232.1 stcD2 stcD2 stcD1 stcD1 dadA4 dadA4 dgoD3 dgoD3 dgoD2 dgoD2 AFL51118.1 AFL51118.1 idnD2 idnD2 AFL50880.1 AFL50880.1 thiO thiO vllY vllY sgaA2 sgaA2 melA1 melA1 garL garL pucG pucG ooxA ooxA ooxB ooxB AFL50629.1 AFL50629.1 tdh2 tdh2 tdh1 tdh1 dadA3 dadA3 AFL50437.1 AFL50437.1 AFL50409.1 AFL50409.1 psdht psdht sgaA1 sgaA1 tdcB2 tdcB2 AFL50358.1 AFL50358.1 ocd2 ocd2 dgoD1 dgoD1 AFL50221.1 AFL50221.1 pcaQ pcaQ pcaH pcaH pcaB pcaB paaK1 paaK1 mmsB mmsB gcl gcl idnD1 idnD1 uxuA2 uxuA2 AFL49844.1 AFL49844.1 uxuA1 uxuA1 lhgO lhgO yfdE yfdE hutI hutI hutH1 hutH1 hutU hutU dgoK dgoK dgoA dgoA dadA2 dadA2 edd edd dadA1 dadA1 AFL48841.1 AFL48841.1 ocd ocd tdcB1 tdcB1 fadJ fadJ putA putA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arcB1Ornithine cyclodeaminase ArcB. (349 aa)
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (401 aa)
AFL54617.1Putative KamA family protein. (350 aa)
slyXProtein slyX; Belongs to the SlyX family. (69 aa)
murQN-acetylmuramic acid 6-phosphate etherase MurQ. (298 aa)
AFL54393.1Amidohydrolase 2. (278 aa)
yjjNPutative L-galactonate oxidoreductase YjjN. (340 aa)
garDD-galactarate dehydratase GarD. (501 aa)
hpcH4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family. (266 aa)
gdhBNAD-specific glutamate dehydrogenase GdhB. (1595 aa)
AFL54275.1Uncharacterized protein. (332 aa)
AFL54155.14-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family. (263 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa)
AFL53935.1Fumarylacetoacetate hydrolase family protein. (338 aa)
dadA5D-amino acid dehydrogenase small subunit DadA. (411 aa)
AFL53879.1Uncharacterized protein. (414 aa)
AFL53878.1Hypothetical protein. (133 aa)
soxBSarcosine oxidase subunit beta. (417 aa)
soxGSarcosine oxidase, gamma subunit. (184 aa)
AFL53812.1N-formylglutamate amidohydrolase. (293 aa)
ltaELow specificity L-threonine aldolase LtaE; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa)
AFL53742.1Zn-dependent hydrolase of the beta-lactamase fold family. (279 aa)
hutH2Histidine ammonia-lyase HutH. (508 aa)
paaAPhenylacetic acid degradation protein PaaA. (333 aa)
paaBPhenylacetic acid degradation protein PaaB. (94 aa)
paaCPhenylacetic acid degradation protein PaaC. (261 aa)
paaDPhenylacetic acid degradation protein PaaD. (174 aa)
AFL53537.1Ring-oxidation complex protein 1 in the phenylacetic acid catabolism pathway. (259 aa)
maoCProtein MaoC. (685 aa)
paaK2Phenylacetate-coenzyme A ligase PaaK; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (436 aa)
paaIAcyl-coenzyme A thioesterase PaaI. (152 aa)
fadB1Fatty acid oxidation complex subunit alpha. (686 aa)
AFL53295.1Oxidoreductase. (376 aa)
tdh4L-threonine 3-dehydrogenase Tdh; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (345 aa)
AFL53086.1Hypothetical protein. (300 aa)
AFL53048.1Putative N-methyl-l-tryptophan oxidase. (393 aa)
AFL53005.1Putative transmembrane protein. (270 aa)
AFL52724.1Uncharacterized protein. (228 aa)
tdh3L-threonine 3-dehydrogenase Tdh. (341 aa)
gcvT3Aminomethyltransferase GcvT. (474 aa)
gcvHGlycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa)
anmKanhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (384 aa)
aldAlanine dehydrogenase Ald; Belongs to the AlaDH/PNT family. (372 aa)
ilvAThreonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (415 aa)
AFL51910.1UPF0173 metal-dependent hydrolase R01310; Belongs to the UPF0173 family. (234 aa)
AFL51801.1Hypothetical protein. (228 aa)
AFL51742.1D-threonine aldolase. (352 aa)
mvaBhydroxymethylglutaryl-CoA lyase MvaB. (289 aa)
AFL51714.1Putative transcriptional regulator, PaaX family. (295 aa)
ocd1Ornithine cyclodeaminase 1. (329 aa)
AFL51705.1Putative threonine dehydratase. (334 aa)
AFL51601.1Ureidoglycolate lyase. (279 aa)
AFL51577.1D-amino acid oxidase protein. (592 aa)
AFL51533.1Putative deaminase. (441 aa)
AFL51232.1Putative 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (301 aa)
stcD2Putative N-methylproline demethylase StcD. (678 aa)
stcD1Putative N-methylproline demethylase StcD. (661 aa)
dadA4D-amino acid dehydrogenase small subunit DadA. (416 aa)
dgoD3D-galactonate dehydratase DgoD; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (395 aa)
dgoD2D-galactonate dehydratase DgoD; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (405 aa)
AFL51118.1Putative FAD dependent oxidoreductase. (397 aa)
idnD2L-idonate 5-dehydrogenase IdnD. (343 aa)
AFL50880.1Oxidoreductase. (375 aa)
thiOPutative thiamine biosynthesis oxidoreductase ThiO. (324 aa)
vllYHemolysin VllY. (629 aa)
sgaA2Serine--glyoxylate aminotransferase SgaA. (396 aa)
melA1Protein MelA. (629 aa)
garL5-keto-4-deoxy-D-glucarate aldolase GarL; Belongs to the HpcH/HpaI aldolase family. (275 aa)
pucGPurine catabolism protein PucG. (370 aa)
ooxAOpine oxidase subunit A. (543 aa)
ooxBOpine oxidase subunit B. (375 aa)
AFL50629.1Putative glycine/D-amino acid oxidase. (440 aa)
tdh2Putative L-threonine 3-dehydrogenase Tdh. (345 aa)
tdh1Putative L-threonine 3-dehydrogenase Tdh. (343 aa)
dadA3D-amino acid dehydrogenase small subunit DadA; Oxidative deamination of D-amino acids. (416 aa)
AFL50437.1L-alanine-DL-glutamate epimerase-like protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (371 aa)
AFL50409.1Hypothetical protein. (291 aa)
psdhtPhenylserine dehydratase. (337 aa)
sgaA1Serine--glyoxylate aminotransferase SgaA. (396 aa)
tdcB2Threonine dehydratase catabolic. (315 aa)
AFL50358.1D-threonine aldolase. (387 aa)
ocd2Ornithine cyclodeaminase 2. (293 aa)
dgoD1D-galactonate dehydratase DgoD. (389 aa)
AFL50221.1Putative mandelate racemase protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (449 aa)
pcaQHTH-type transcriptional regulator PcaQ; Belongs to the LysR transcriptional regulatory family. (308 aa)
pcaHProtocatechuate 3,4-dioxygenase beta chain. (249 aa)
pcaB3-carboxy-cis,cis-muconate cycloisomerase. (420 aa)
paaK1Phenylacetate-coenzyme A ligase PaaK. (436 aa)
mmsBPutative 3-hydroxyisobutyrate dehydrogenase MmsB; Belongs to the HIBADH-related family. (298 aa)
gclGlyoxylate carboligase Gcl; Belongs to the TPP enzyme family. (594 aa)
idnD1L-idonate 5-dehydrogenase IdnD. (355 aa)
uxuA2Mannonate dehydratase UxuA; Catalyzes the dehydration of D-mannonate. (398 aa)
AFL49844.1Anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase component. (408 aa)
uxuA1Mannonate dehydratase UxuA; Catalyzes the dehydration of D-mannonate. (324 aa)
lhgOL-2-hydroxyglutarate oxidase LhgO. (366 aa)
yfdEUncharacterized protein YfdE; Belongs to the CoA-transferase III family. (396 aa)
hutIImidazolonepropionase HutI. (415 aa)
hutH1Histidine ammonia-lyase HutH. (511 aa)
hutUUrocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (559 aa)
dgoK2-dehydro-3-deoxygalactonokinase DgoK. (305 aa)
dgoA2-dehydro-3-deoxy-6-phosphogalactonate aldolase DgoA. (213 aa)
dadA2D-amino acid dehydrogenase small subunit DadA. (417 aa)
eddPhosphogluconate dehydratase Edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (620 aa)
dadA1D-amino acid dehydrogenase small subunit DadA; Oxidative deamination of D-amino acids. (415 aa)
AFL48841.1Putative oxidoreductase. (444 aa)
ocdOrnithine cyclodeaminase. (330 aa)
tdcB1Threonine dehydratase catabolic. (325 aa)
fadJFatty acid oxidation complex subunit alpha. (737 aa)
putABifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1311 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
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