STRINGSTRING
rbsK1 rbsK1 pgi pgi edd edd pgl pgl zwf zwf gdh gdh deoC deoC rbsK2 rbsK2 phnN1 phnN1 fba fba algC algC AFL50073.1 AFL50073.1 AFL50074.1 AFL50074.1 ttuD1 ttuD1 tal1 tal1 tktA tktA AFL50451.1 AFL50451.1 AFL50452.1 AFL50452.1 rbsK3 rbsK3 AFL50468.1 AFL50468.1 AFL50694.1 AFL50694.1 rbsK rbsK gnl1 gnl1 idnK idnK gnl2 gnl2 cbbE1 cbbE1 cbbA cbbA cbbT1 cbbT1 fbp fbp cbbE2 cbbE2 AFL52512.1 AFL52512.1 rpiA rpiA yqjI yqjI pfp pfp prs prs kdgK kdgK cbbT2 cbbT2 AFL53756.1 AFL53756.1 pgm pgm eda eda tal2 tal2 ttuD2 ttuD2 deoB deoB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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rbsK1Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
pgiGlucose-6-phosphate isomerase Pgi; Belongs to the GPI family. (541 aa)
eddPhosphogluconate dehydratase Edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (620 aa)
pgl6-phosphogluconolactonase Pgl; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa)
zwfGlucose-6-phosphate 1-dehydrogenase Zwf; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
gdhQuinoprotein glucose dehydrogenase Gdh. (778 aa)
deoCDeoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (337 aa)
rbsK2Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
phnN1Ribose 1,5-bisphosphate phosphokinase PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (195 aa)
fbaFructose-bisphosphate aldolase Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (348 aa)
algCPhosphomannomutase/phosphoglucomutase AlgC. (516 aa)
AFL50073.1Putative transketolase N-terminal section. (269 aa)
AFL50074.1Putative transketolase C-terminal section. (322 aa)
ttuD1Putative hydroxypyruvate reductase TtuD. (422 aa)
tal1Putative transaldolase Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
tktATransketolase TktA; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (675 aa)
AFL50451.1Putative transketolase N-terminal section. (273 aa)
AFL50452.1Putative transketolase C-terminal section. (322 aa)
rbsK3Ribokinase RbsK. (292 aa)
AFL50468.1Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. (264 aa)
AFL50694.1Putative phosphoketolase 1. (820 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (332 aa)
gnl1Gluconolactonase Gnl. (304 aa)
idnKThermosensitive gluconokinase IdnK. (163 aa)
gnl2Gluconolactonase Gnl. (298 aa)
cbbE1Ribulose-phosphate 3-epimerase CbbE; Belongs to the ribulose-phosphate 3-epimerase family. (229 aa)
cbbAFructose-bisphosphate aldolase CbbA; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
cbbT1Transketolase CbbT; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (681 aa)
fbpFructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family. (349 aa)
cbbE2Ribulose-phosphate 3-epimerase CbbE; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
AFL52512.1Putative phosphoketolase 2. (789 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
yqjI6-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
pfpPyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfp; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (404 aa)
prsRibose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
kdgK2-dehydro-3-deoxygluconokinase KdgK. (306 aa)
cbbT2Transketolase CbbT; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa)
AFL53756.1Putative fructose-bisphosphate aldolase class 1. (341 aa)
pgmPhosphoglucomutase Pgm. (542 aa)
eda2-dehydro-3-deoxy-phosphogluconate aldolase Eda. (212 aa)
tal2Putative transaldolase Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
ttuD2Putative hydroxypyruvate reductase TtuD. (491 aa)
deoBPhosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (406 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
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