STRINGSTRING
dapE dapE dapD-2 dapD-2 argD1 argD1 dapA1 dapA1 AFL49856.1 AFL49856.1 dapA2 dapA2 AFL50981.1 AFL50981.1 AFL51091.1 AFL51091.1 dapAf2 dapAf2 dapA3 dapA3 AFL51354.1 AFL51354.1 hom hom murF murF murE murE lysC lysC lysA lysA dapF dapF asd asd dapB dapB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
dapESuccinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (398 aa)
dapD-22,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (285 aa)
argD1Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
dapA1Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
AFL49856.1Putative DAPA-like lyase; Belongs to the DapA family. (331 aa)
dapA2Dihydrodipicolinate synthase DapA; Belongs to the DapA family. (302 aa)
AFL50981.1Uncharacterized protein y4yA. (457 aa)
AFL51091.1Hypothetical protein; Belongs to the DapA family. (319 aa)
dapAf2Dihydrodipicolinate synthase protein; Belongs to the DapA family. (315 aa)
dapA3Dihydrodipicolinate synthase DapA; Belongs to the DapA family. (292 aa)
AFL51354.1Dihydrodipicolinate synthase; Belongs to the DapA family. (297 aa)
homHomoserine dehydrogenase Hom. (440 aa)
murFPutative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (482 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
lysCAspartokinase LysC; Belongs to the aspartokinase family. (424 aa)
lysADiaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa)
dapFDiaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (300 aa)
asdAspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
dapBDihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (272 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
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