STRINGSTRING
yidC yidC AFL48703.1 AFL48703.1 fadD fadD secDF1 secDF1 gsiA1 gsiA1 appA appA appB1 appB1 appC1 appC1 AFL49134.1 AFL49134.1 yhfT yhfT AFL49238.1 AFL49238.1 AFL49481.1 AFL49481.1 ribD ribD kdpE kdpE AFL49563.1 AFL49563.1 AFL49564.1 AFL49564.1 AFL49565.1 AFL49565.1 livG1 livG1 livF1 livF1 AFL49585.1 AFL49585.1 potH2 potH2 AFL49587.1 AFL49587.1 oppA1 oppA1 oppB oppB oppC1 oppC1 yejF1 yejF1 AFL49777.1 AFL49777.1 gsiA2 gsiA2 ddpC1 ddpC1 dppB2 dppB2 ddpA1 ddpA1 potA1 potA1 AFL49833.1 AFL49833.1 potB1 potB1 potD potD oppA2 oppA2 dppC2 dppC2 oppD1 oppD1 appF1 appF1 potA2 potA2 AFL50333.1 AFL50333.1 AFL50337.1 AFL50337.1 livF3 livF3 AFL50420.1 AFL50420.1 livH1 livH1 livG3 livG3 AFL50423.1 AFL50423.1 AFL50430.1 AFL50430.1 livH2 livH2 livG4 livG4 AFL50433.1 AFL50433.1 livF4 livF4 rssB rssB braC braC AFL50717.1 AFL50717.1 AFL50718.1 AFL50718.1 livG5 livG5 livF5 livF5 agpA1 agpA1 appB2 appB2 appC2 appC2 yejF2 yejF2 AFL50972.1 AFL50972.1 ykfD1 ykfD1 oppD2 oppD2 ddpC2 ddpC2 AFL50997.1 AFL50997.1 gsiB gsiB agpA2 agpA2 appB3 appB3 appC3 appC3 gsiA3 gsiA3 gsiA4 gsiA4 dppC3 dppC3 gsiC1 gsiC1 dppA2 dppA2 AFL51795.1 AFL51795.1 gsiA5 gsiA5 agpA3 agpA3 appB4 appB4 appC4 appC4 secY secY AFL52034.1 AFL52034.1 hfq hfq yajC yajC secDF2 secDF2 AFL52238.1 AFL52238.1 AFL52328.1 AFL52328.1 AFL52656.1 AFL52656.1 traI traI aroH aroH fur-2 fur-2 AFL52996.1 AFL52996.1 AFL52997.1 AFL52997.1 livM livM braF1 braF1 braG braG AFL53079.1 AFL53079.1 AFL53080.1 AFL53080.1 AFL53081.1 AFL53081.1 potA9 potA9 dppA3 dppA3 gsiC2 gsiC2 dppC4 dppC4 gsiA6 gsiA6 ydcS ydcS ydcT ydcT ydcU ydcU ydcV ydcV ykfD2 ykfD2 oppD3 oppD3 dppC5 dppC5 dppB4 dppB4 ddpA2 ddpA2 AFL53478.1 AFL53478.1 livF6 livF6 livG6 livG6 braE1 braE1 livH3 livH3 AFL53493.1 AFL53493.1 AFL53494.1 AFL53494.1 potA10 potA10 AFL53496.1 AFL53496.1 livF7 livF7 braF2 braF2 braE2 braE2 natD natD AFL53530.1 AFL53530.1 secA secA appC5 appC5 gsiC3 gsiC3 appF2 appF2 oppD4 oppD4 dppA4 dppA4 AFL53757.1 AFL53757.1 AFL53973.1 AFL53973.1 AFL53974.1 AFL53974.1 AFL53975.1 AFL53975.1 AFL53976.1 AFL53976.1 AFL53977.1 AFL53977.1 nikA nikA oppC2 oppC2 gsiA7 gsiA7 ftsY ftsY ffh ffh AFL54305.1 AFL54305.1 secB secB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yidCMembrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (593 aa)
AFL48703.1Putative transcriptional regulator, Crp/Fnr family. (234 aa)
fadDlong-chain-fatty-acid--CoA ligase FadD. (566 aa)
secDF1Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (844 aa)
gsiA1Glutathione import ATP-binding protein GsiA; Belongs to the ABC transporter superfamily. (554 aa)
appAOligopeptide-binding protein AppA. (554 aa)
appB1Oligopeptide transport system permease protein AppB. (316 aa)
appC1Oligopeptide transport system permease protein AppC. (292 aa)
AFL49134.1Putative LuxR/GerE family transcriptional regulator. (245 aa)
yhfTPutative acyl--CoA ligase YhfT. (498 aa)
AFL49238.1Leu/Ile/Val-binding protein. (368 aa)
AFL49481.1Putative ABC-transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (298 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
kdpETranscriptional regulatory protein KdpE. (232 aa)
AFL49563.1Leu/Ile/Val-binding protein. (390 aa)
AFL49564.1Putative transmembrane component of ABC transporter; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
AFL49565.1Branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (335 aa)
livG1High-affinity branched-chain amino acid transport ATP-binding protein LivG. (254 aa)
livF1High-affinity branched-chain amino acid transport ATP-binding protein LivF. (238 aa)
AFL49585.1Putative spermidine/putrescine ABC transporter, permease protein. (273 aa)
potH2Putrescine transport system permease protein PotH. (302 aa)
AFL49587.1ABC transporter, binding protein. (432 aa)
oppA1Periplasmic oligopeptide-binding protein OppA. (532 aa)
oppBOligopeptide transport system permease protein OppB. (307 aa)
oppC1Oligopeptide transport system permease protein OppC. (376 aa)
yejF1Putative ABC transporter ATP-binding protein YejF; Belongs to the ABC transporter superfamily. (542 aa)
AFL49777.1Leu/Ile/Val-binding protein. (364 aa)
gsiA2Glutathione import ATP-binding protein GsiA. (283 aa)
ddpC1Putative D,D-dipeptide transport system permease protein DdpC. (301 aa)
dppB2Dipeptide transport system permease protein DppB. (342 aa)
ddpA1Putative D,D-dipeptide-binding periplasmic protein DdpA. (530 aa)
potA1Spermidine/putrescine import ATP-binding protein PotA; Belongs to the ABC transporter superfamily. (360 aa)
AFL49833.1ABC-type transporter, integral membrane subunit. (266 aa)
potB1Spermidine/putrescine transport system permease protein PotB. (290 aa)
potDSpermidine/putrescine-binding periplasmic protein. (336 aa)
oppA2Periplasmic oligopeptide-binding protein OppA. (549 aa)
dppC2Dipeptide transport system permease protein DppC. (319 aa)
oppD1Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily. (335 aa)
appF1Oligopeptide transport ATP-binding protein AppF; Belongs to the ABC transporter superfamily. (327 aa)
potA2Spermidine/putrescine import ATP-binding protein PotA; Belongs to the ABC transporter superfamily. (379 aa)
AFL50333.1Extracellular solute-binding protein family 1. (361 aa)
AFL50337.1Binding-protein-dependent transport systems inner membrane component. (572 aa)
livF3High-affinity branched-chain amino acid transport ATP-binding protein LivF. (239 aa)
AFL50420.1Putative branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (370 aa)
livH1High-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
livG3High-affinity branched-chain amino acid transport ATP-binding protein LivG. (251 aa)
AFL50423.1Extracellular ligand-binding receptor. (399 aa)
AFL50430.1Putative branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (365 aa)
livH2High-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
livG4High-affinity branched-chain amino acid transport ATP-binding protein LivG. (251 aa)
AFL50433.1Extracellular ligand-binding receptor. (402 aa)
livF4High-affinity branched-chain amino acid transport ATP-binding protein LivF. (253 aa)
rssBSwarming motility regulation protein RssB. (223 aa)
braCLeucine-, isoleucine-, valine-, threonine-, and alanine-binding protein BraC. (379 aa)
AFL50717.1Putative branched-chain amino acid ABC transporter; Belongs to the binding-protein-dependent transport system permease family. (292 aa)
AFL50718.1Putative branched-chain amino acid ABC transporter; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
livG5Putative branched-chain amino acid transport ATP-binding protein LivG. (247 aa)
livF5High-affinity branched-chain amino acid transport ATP-binding protein LivF. (239 aa)
agpA1Periplasmic alpha-galactoside-binding protein AgpA. (693 aa)
appB2Oligopeptide transport system permease protein AppB. (337 aa)
appC2Oligopeptide transport system permease protein AppC. (375 aa)
yejF2Putative ABC transporter ATP-binding protein YejF; Belongs to the ABC transporter superfamily. (556 aa)
AFL50972.1Hypothetical protein. (100 aa)
ykfD1Putative oligopeptide transport ATP-binding protein YkfD; Belongs to the ABC transporter superfamily. (329 aa)
oppD2Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily. (323 aa)
ddpC2Putative D,D-dipeptide transport system permease protein DdpC. (305 aa)
AFL50997.1Putative peptide transport system permease protein. (306 aa)
gsiBGlutathione-binding protein GsiB. (507 aa)
agpA2Periplasmic alpha-galactoside-binding protein AgpA. (649 aa)
appB3Oligopeptide transport system permease protein AppB. (328 aa)
appC3Oligopeptide transport system permease protein AppC. (373 aa)
gsiA3Glutathione import ATP-binding protein GsiA; Belongs to the ABC transporter superfamily. (573 aa)
gsiA4Glutathione import ATP-binding protein GsiA; Belongs to the ABC transporter superfamily. (552 aa)
dppC3Dipeptide transport system permease protein DppC. (288 aa)
gsiC1Glutathione transport system permease protein GsiC. (316 aa)
dppA2Periplasmic dipeptide transport protein DppA. (536 aa)
AFL51795.1Hypothetical protein. (493 aa)
gsiA5Glutathione import ATP-binding protein GsiA; Belongs to the ABC transporter superfamily. (630 aa)
agpA3Periplasmic alpha-galactoside-binding protein AgpA. (633 aa)
appB4Oligopeptide transport system permease protein AppB. (332 aa)
appC4Oligopeptide transport system permease protein AppC. (391 aa)
secYProtein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (446 aa)
AFL52034.1Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (168 aa)
hfqProtein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (80 aa)
yajCImmunogenic membrane protein YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
secDF2Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (855 aa)
AFL52238.1Putative binding protein. (609 aa)
AFL52328.1Putative solute-binding component of ABC transporter. (362 aa)
AFL52656.1Transcriptional regulator NgrR, LuxR family. (245 aa)
traIAcyl-homoserine-lactone synthase TraI. (214 aa)
aroHPhospho-2-dehydro-3-deoxyheptonate aldolase AroH. (457 aa)
fur-2Zinc uptake transcriptional regulator protein, Fur family; Belongs to the Fur family. (131 aa)
AFL52996.1Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein. (399 aa)
AFL52997.1Branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
livMHigh-affinity branched-chain amino acid transport system permease protein LivM; Belongs to the binding-protein-dependent transport system permease family. (328 aa)
braF1High-affinity branched-chain amino acid transport ATP-binding protein BraF. (259 aa)
braGHigh-affinity branched-chain amino acid transport ATP-binding protein BraG. (240 aa)
AFL53079.1Putative periplasmic binding ABC transporter. (367 aa)
AFL53080.1Transport system permease protein. (316 aa)
AFL53081.1Binding-protein-dependent transport systems inner membrane component. (262 aa)
potA9Spermidine/putrescine import ATP-binding protein PotA; Belongs to the ABC transporter superfamily. (353 aa)
dppA3Periplasmic dipeptide transport protein DppA. (529 aa)
gsiC2Glutathione transport system permease protein GsiC. (370 aa)
dppC4Dipeptide transport system permease protein DppC. (275 aa)
gsiA6Glutathione import ATP-binding protein GsiA; Belongs to the ABC transporter superfamily. (543 aa)
ydcSPutative ABC transporter periplasmic-binding protein YdcS. (386 aa)
ydcTPutative ABC transporter ATP-binding protein YdcT; Belongs to the ABC transporter superfamily. (332 aa)
ydcUInner membrane ABC transporter permease protein YdcU. (316 aa)
ydcVInner membrane ABC transporter permease protein YdcV. (271 aa)
ykfD2Putative oligopeptide transport ATP-binding protein YkfD. (251 aa)
oppD3Oligopeptide transport ATP-binding protein OppD. (277 aa)
dppC5Dipeptide transport system permease protein DppC. (310 aa)
dppB4Dipeptide transport system permease protein DppB. (353 aa)
ddpA2Putative D,D-dipeptide-binding periplasmic protein DdpA. (546 aa)
AFL53478.1Leu/Ile/Val-binding protein. (372 aa)
livF6High-affinity branched-chain amino acid transport ATP-binding protein LivF. (241 aa)
livG6High-affinity branched-chain amino acid transport ATP-binding protein LivG. (295 aa)
braE1High-affinity branched-chain amino acid transport system permease protein BraE; Belongs to the binding-protein-dependent transport system permease family. (461 aa)
livH3High-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family. (300 aa)
AFL53493.1Binding-protein-dependent transport systems inner membrane component. (266 aa)
AFL53494.1ABC transporter permease protein. (284 aa)
potA10Spermidine/putrescine import ATP-binding protein PotA; Belongs to the ABC transporter superfamily. (345 aa)
AFL53496.1Putative substrate-binding component of ABC transporter. (359 aa)
livF7High-affinity branched-chain amino acid transport ATP-binding protein LivF. (233 aa)
braF2High-affinity branched-chain amino acid transport ATP-binding protein BraF. (261 aa)
braE2High-affinity branched-chain amino acid transport system permease protein BraE; Belongs to the binding-protein-dependent transport system permease family. (318 aa)
natDInner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (290 aa)
AFL53530.1Extracellular ligand-binding receptor. (381 aa)
secAProtein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (901 aa)
appC5Oligopeptide transport system permease protein AppC. (293 aa)
gsiC3Glutathione transport system permease protein GsiC. (308 aa)
appF2Oligopeptide transport ATP-binding protein AppF; Belongs to the ABC transporter superfamily. (331 aa)
oppD4Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily. (337 aa)
dppA4Periplasmic dipeptide transport protein DppA. (542 aa)
AFL53757.1Putative isomerase. (304 aa)
AFL53973.1Putative substrate-binding component of ABC transporter. (420 aa)
AFL53974.1Putative ATP-binding component of ABC transporter. (260 aa)
AFL53975.1Putative ATP-binding component of ABC transporter. (233 aa)
AFL53976.1Putative permease component of ABC transporter; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
AFL53977.1ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (330 aa)
nikANickel-binding periplasmic protein NikA. (506 aa)
oppC2Putative oligopeptide transport system permease protein OppC2. (274 aa)
gsiA7Glutathione import ATP-binding protein GsiA. (473 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (351 aa)
ffhSignal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] (519 aa)
AFL54305.1Putative transcription regulator. (140 aa)
secBProtein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (210 aa)
Your Current Organism:
Sinorhizobium fredii USDA257
NCBI taxonomy Id: 1185652
Other names: S. fredii USDA 257, Sinorhizobium fredii USDA 257, Sinorhizobium fredii str. USDA 257, Sinorhizobium fredii strain USDA 257
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