STRINGSTRING
SOS2 SOS2 SHC3 SHC3 SRC SRC SOS1 SOS1 CRKL CRKL RAPGEF1 RAPGEF1 CRK CRK CBL CBL GRB2 GRB2 GAB2 GAB2 SHC1 SHC1 FGR FGR SHC2 SHC2 BCAR1 BCAR1 GAB1 GAB1 PTK2B PTK2B PTK2 PTK2 PTPN11 PTPN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOS2Son of sevenless homolog 2-like. (1272 aa)
SHC3SHC-transforming protein 3. (588 aa)
SRCTyrosine-protein kinase. (548 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
CRKLCrk-like protein. (303 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1133 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
GAB2GRB2-associated-binding protein 2. (640 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
FGRTyrosine-protein kinase. (537 aa)
SHC2SHC-transforming protein 2. (801 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X1. (867 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (723 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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