STRINGSTRING
RHOA RHOA RND3 RND3 CYFIP2 CYFIP2 LOC103069874 LOC103069874 LOC103070587 LOC103070587 LRP12 LRP12 ACTA1 ACTA1 ACTB ACTB NCKIPSD NCKIPSD LOC103080995 LOC103080995 LOC103090788 LOC103090788 KCTD10 KCTD10 RHOF RHOF ARPC1B ARPC1B RASA1 RASA1 ARPC5 ARPC5 SRGAP1 SRGAP1 TMEM120B TMEM120B GIT2 GIT2 ARPC1A ARPC1A WAS WAS ARHGAP31 ARHGAP31 ABL2 ABL2 LOC103082455 LOC103082455 ARPC3 ARPC3 ARPC2 ARPC2 WIPF1 WIPF1 ARHGAP5 ARHGAP5 LOC103071630 LOC103071630 LOC103080281 LOC103080281 RND2 RND2 WASF1 WASF1 ARPC5L ARPC5L TNFAIP1 TNFAIP1 GIT1 GIT1 ARHGEF12 ARHGEF12 LOC103074582 LOC103074582 GPBAR1 GPBAR1 ARHGDIG ARHGDIG ARPC4 ARPC4 PAK7 PAK7 ARHGEF6 ARHGEF6 RHOH RHOH ARHGEF7 ARHGEF7 EVL EVL DIAPH2 DIAPH2 ABI2 ABI2 GNA13 GNA13 ENAH ENAH NCK2 NCK2 ARHGDIB ARHGDIB FMNL1 FMNL1 NCKAP1 NCKAP1 ARHGEF11 ARHGEF11 PFN4 PFN4 SH3RF3 SH3RF3 ARHGAP35 ARHGAP35 ARHGEF1 ARHGEF1 NCK1 NCK1 MYO6 MYO6 ROCK2 ROCK2 PFN1 PFN1 IQGAP3 IQGAP3 TRIP10 TRIP10 CALM3 CALM3 VASP VASP LOC103077822 LOC103077822 WASF2 WASF2 CDC42 CDC42 RHOC RHOC RHOJ RHOJ MYO9B MYO9B ARHGDIA ARHGDIA BAIAP2 BAIAP2 RHOQ RHOQ PAK6 PAK6 LOC103079784 LOC103079784 IQGAP2 IQGAP2 PAK1 PAK1 SRGAP3 SRGAP3 RHOB RHOB LOC103078777 LOC103078777 FMNL2 FMNL2 RAC3 RAC3 FMN1 FMN1 PAK4 PAK4 CYFIP1 CYFIP1 PFN3 PFN3 WIPF2 WIPF2 PAK2 PAK2 LOC103069126 LOC103069126 ACTR2 ACTR2 PAK3 PAK3 FHDC1 FHDC1 LOC103081078 LOC103081078 SCRN2 SCRN2 GAS2L3 GAS2L3 GNA12 GNA12 WIPF3 WIPF3 MYO9A MYO9A DIAPH1 DIAPH1 FAM212A FAM212A SPIRE2 SPIRE2 LOC103075410 LOC103075410 NCKAP1L NCKAP1L LOC103087242 LOC103087242 FNBP1L FNBP1L ITSN1 ITSN1 IQGAP1 IQGAP1 ABI1 ABI1 FAM129B FAM129B SRGAP2 SRGAP2 ARHGAP10 ARHGAP10 PFN2 PFN2 ACTR3B ACTR3B SPIRE1 SPIRE1 WASF3 WASF3 PDLIM1 PDLIM1 FNBP1 FNBP1 WASL WASL LOC103090824 LOC103090824
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOATransforming protein RhoA isoform X1. (221 aa)
RND3Rho-related GTP-binding protein RhoE. (244 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
LOC103069874Abl interactor 1-like. (235 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
LRP12Low-density lipoprotein receptor-related protein 12 isoform X1. (859 aa)
ACTA1Actin, alpha skeletal muscle isoform X1. (377 aa)
ACTBActin, cytoplasmic 1. (375 aa)
NCKIPSDNCK-interacting protein with SH3 domain isoform X1. (721 aa)
LOC103080995SLIT-ROBO Rho GTPase-activating protein 1-like. (455 aa)
LOC103090788Rho-related GTP-binding protein RhoU-like. (255 aa)
KCTD10BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3. (315 aa)
RHOFRho-related GTP-binding protein RhoF. (211 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1-like. (604 aa)
TMEM120BTransmembrane protein 120B. (339 aa)
GIT2ARF GTPase-activating protein GIT2 isoform X1. (758 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
ARHGAP31Rho GTPase-activating protein 31. (1452 aa)
ABL2Tyrosine-protein kinase. (1067 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
WIPF1WAS/WASL-interacting protein family member 1-like. (495 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
LOC103071630LOW QUALITY PROTEIN: protein diaphanous homolog 3-like. (1083 aa)
LOC103080281Probable protein BRICK1-like. (75 aa)
RND2Rho-related GTP-binding protein RhoN. (233 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
TNFAIP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2. (316 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
ARHGEF12LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 12. (1563 aa)
LOC103074582SH3 domain-containing RING finger protein 3-like. (705 aa)
GPBAR1G-protein coupled bile acid receptor 1. (329 aa)
ARHGDIGRho GDP-dissociation inhibitor 3. (225 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
PAK7Non-specific serine/threonine protein kinase. (719 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6. (777 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X2. (803 aa)
EVLena/VASP-like protein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (419 aa)
DIAPH2Protein diaphanous homolog 2. (1100 aa)
ABI2Abl interactor 2 isoform X1. (540 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
ENAHProtein enabled homolog. (560 aa)
NCK2Cytoplasmic protein. (376 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (199 aa)
FMNL1Formin-like protein 1. (1102 aa)
NCKAP1Nck-associated protein 1. (1126 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform X1. (1559 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
SH3RF3SH3 domain-containing RING finger protein 3. (152 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1 isoform X1. (913 aa)
NCK1Cytoplasmic protein. (377 aa)
MYO6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1612 aa)
TRIP10LOW QUALITY PROTEIN: cdc42-interacting protein 4. (601 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
VASPVasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (384 aa)
LOC103077822Profilin; Belongs to the profilin family. (127 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
RHOCRho-related GTP-binding protein RhoC. (193 aa)
RHOJRho-related GTP-binding protein RhoJ. (236 aa)
MYO9BUnconventional myosin-IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2153 aa)
ARHGDIARho GDP-dissociation inhibitor 1 isoform X1. (204 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
RHOQRho-related GTP-binding protein RhoQ. (197 aa)
PAK6Non-specific serine/threonine protein kinase. (675 aa)
LOC103079784Uncharacterized protein. (610 aa)
IQGAP2LOW QUALITY PROTEIN: ras GTPase-activating-like protein IQGAP2. (1577 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
SRGAP3SLIT-ROBO Rho GTPase-activating protein 3. (1030 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
LOC103078777Rho-related GTP-binding protein RhoQ-like isoform X1. (249 aa)
FMNL2Formin-like protein 2 isoform X3. (1083 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
FMN1Formin-1 isoform X1. (1420 aa)
PAK4Non-specific serine/threonine protein kinase. (591 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
WIPF2WAS/WASL-interacting protein family member 2 isoform X1. (440 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
LOC103069126Actin-related protein 3-like isoform X1; Belongs to the actin family. (418 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (579 aa)
FHDC1LOW QUALITY PROTEIN: FH2 domain-containing protein 1. (1127 aa)
LOC103081078Leucine-rich repeat extensin-like protein 5-like. (449 aa)
SCRN2Secernin-2 isoform X1. (441 aa)
GAS2L3GAS2-like protein 3. (696 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (480 aa)
WIPF3WAS/WASL-interacting protein family member 3. (416 aa)
MYO9ALOW QUALITY PROTEIN: unconventional myosin-IXa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2568 aa)
DIAPH1Protein diaphanous homolog 1 isoform X2. (1236 aa)
FAM212AProtein FAM212A. (283 aa)
SPIRE2Protein spire homolog 2. (725 aa)
LOC103075410Rho-related GTP-binding protein RhoQ-like. (205 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
LOC103087242Profilin; Belongs to the profilin family. (134 aa)
FNBP1LFormin-binding protein 1-like. (459 aa)
ITSN1Intersectin-1-like. (616 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1627 aa)
ABI1Abl interactor 1-like isoform X1. (379 aa)
FAM129BNiban-like protein 1. (748 aa)
SRGAP2SLIT-ROBO Rho GTPase-activating protein 2 isoform X1. (1071 aa)
ARHGAP10Rho GTPase-activating protein 10. (786 aa)
PFN2Profilin; Belongs to the profilin family. (143 aa)
ACTR3BActin-related protein 3B-like isoform X1; Belongs to the actin family. (418 aa)
SPIRE1LOW QUALITY PROTEIN: spire-type actin nucleation factor 1. (571 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
PDLIM1PDZ and LIM domain protein 1. (329 aa)
FNBP1Formin-binding protein 1-like. (537 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
LOC103090824Formin-2-like. (1322 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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