STRINGSTRING
GC GC SERPINA1 SERPINA1 MST1 MST1 SERPINA10 SERPINA10 AMBP AMBP SERPINA4 SERPINA4 CMA1 CMA1 SERPINA5 SERPINA5 SPINK6 SPINK6 PROCR PROCR LOC103080187 LOC103080187 MET MET SPINK1 SPINK1 EPX EPX MASP1 MASP1 MMP8 MMP8 FGA FGA LOC103086154 LOC103086154 LOC103082565 LOC103082565 FGB FGB KRT80 KRT80 TMPRSS12 TMPRSS12 ITIH1 ITIH1 TMPRSS11E TMPRSS11E HRG HRG PRSS8 PRSS8 CFP CFP LOC103068503 LOC103068503 CDC37L1 CDC37L1 FETUB FETUB TFPI2 TFPI2 AHSG AHSG COLEC10 COLEC10 LOC103084777 LOC103084777 SERPIND1 SERPIND1 LOC103075550 LOC103075550 LOC103072836 LOC103072836 SERPINB6 SERPINB6 C5 C5 ITIH3 ITIH3 SLCO1B3 SLCO1B3 F9 F9 LOC103079579 LOC103079579 ADAMTS13 ADAMTS13 TSPYL1 TSPYL1 PRSS33 PRSS33 LOC103089778 LOC103089778 SERPINF1 SERPINF1 F2 F2 SERPINF2 SERPINF2 APOH APOH CTRL CTRL SERPING1 SERPING1 CD177 CD177 ST14 ST14 C8G C8G HGFAC HGFAC MYOM3 MYOM3 C1QA C1QA C1QB C1QB LOC103090225 LOC103090225 CELA3B CELA3B CTRC CTRC CFB CFB PTK7 PTK7 LOC103079033 LOC103079033 LOC103073034 LOC103073034 CD93 CD93 THBD THBD SPINT1 SPINT1 F5 F5 AZU1 AZU1 C1QC C1QC LOC103076380 LOC103076380 C2 C2 F13B F13B HPX HPX C9 C9 CELA2A CELA2A C4A C4A SERPINA7 SERPINA7 ELANE ELANE CFD CFD LOC103074903 LOC103074903 C8A C8A PRTN3 PRTN3 LOC103078577 LOC103078577 C3 C3 F12 F12 PROS1 PROS1 MASP2 MASP2 PROC PROC KLK1 KLK1 LECT2 LECT2 KLK6 KLK6 C8B C8B SERPINB10 SERPINB10 MS4A3 MS4A3 LOC103087584 LOC103087584 LRIT3 LRIT3 KLK12 KLK12 SERPINB12 SERPINB12 CTRB1 CTRB1 LOC103078294 LOC103078294 KLK14 KLK14 KLK5 KLK5 KLK7 KLK7 DGKE DGKE SPP2 SPP2 MST1R MST1R PROZ PROZ LOC103082086 LOC103082086 F11 F11 LOC103082631 LOC103082631 LOC103078500 LOC103078500 LOC103083722 LOC103083722 LOC103082362 LOC103082362 F10 F10 CD59 CD59 F7 F7 F13A1 F13A1 AFM AFM HGF HGF CD97 CD97 ALB ALB C1RL C1RL LOC103078895 LOC103078895 LOC103069153 LOC103069153 C7 C7 CPA1 CPA1 LOC103091086 LOC103091086 F3 F3 COLEC11 COLEC11 LOC103077690 LOC103077690 C6 C6 MBL2 MBL2 C1R C1R LOC103087891 LOC103087891 HABP2 HABP2 C3AR1 C3AR1 C1S C1S CR2 CR2 HPN HPN C4BPB C4BPB CPA2 CPA2 FCN1 FCN1 SERPINC1 SERPINC1 CD55 CD55 SPINT2 SPINT2 CPA3 CPA3 SPINK5 SPINK5 CTSG CTSG CR1 CR1 GZMH GZMH TFPI TFPI SERPINB9 SERPINB9 TMPRSS11F TMPRSS11F LOC103081213 LOC103081213 FCN3 FCN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCVitamin D-binding protein. (475 aa)
SERPINA1Alpha-1-antitrypsin isoform X1; Belongs to the serpin family. (422 aa)
MST1Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
SERPINA10Protein Z-dependent protease inhibitor; Belongs to the serpin family. (446 aa)
AMBPProtein AMBP. (352 aa)
SERPINA4LOW QUALITY PROTEIN: kallistatin; Belongs to the serpin family. (456 aa)
CMA1LOW QUALITY PROTEIN: chymase; Belongs to the peptidase S1 family. (247 aa)
SERPINA5Plasma serine protease inhibitor; Belongs to the serpin family. (404 aa)
SPINK6Serine protease inhibitor Kazal-type 6. (114 aa)
PROCREndothelial protein C receptor. (242 aa)
LOC103080187Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family. (202 aa)
METHepatocyte growth factor receptor isoform X1. (1412 aa)
SPINK1Pancreatic secretory trypsin inhibitor. (79 aa)
EPXEosinophil peroxidase. (715 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (728 aa)
MMP8Neutrophil collagenase. (468 aa)
FGAFibrinogen alpha chain. (605 aa)
LOC103086154Complement component receptor 1-like protein-like. (240 aa)
LOC103082565Kunitz-type protease inhibitor 2-like. (247 aa)
FGBFibrinogen beta chain isoform X1. (488 aa)
KRT80Keratin, type II cytoskeletal 80 isoform X1; Belongs to the intermediate filament family. (452 aa)
TMPRSS12Transmembrane protease serine 12; Belongs to the peptidase S1 family. (355 aa)
ITIH1Inter-alpha-trypsin inhibitor heavy chain H1 isoform X1. (944 aa)
TMPRSS11ETransmembrane protease serine; Belongs to the peptidase S1 family. (435 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (472 aa)
PRSS8Prostasin isoform X1; Belongs to the peptidase S1 family. (344 aa)
CFPLOW QUALITY PROTEIN: properdin. (469 aa)
LOC103068503LOW QUALITY PROTEIN: fibrinogen gamma-B chain-like. (445 aa)
CDC37L1Hsp90 co-chaperone Cdc37-like 1 isoform X1. (376 aa)
FETUBfetuin-B. (384 aa)
TFPI2Tissue factor pathway inhibitor. (234 aa)
AHSGalpha-2-HS-glycoprotein. (365 aa)
COLEC10Collectin-10. (277 aa)
LOC103084777Ficolin-1-like. (323 aa)
SERPIND1Heparin cofactor 2; Belongs to the serpin family. (496 aa)
LOC103075550Tryptase-like; Belongs to the peptidase S1 family. (275 aa)
LOC103072836Putative serine protease 41-like. (364 aa)
SERPINB6Serpin B6; Belongs to the serpin family. (373 aa)
C5LOW QUALITY PROTEIN: complement C5. (1677 aa)
ITIH3Inter-alpha-trypsin inhibitor heavy chain H3 isoform X1. (889 aa)
SLCO1B3Solute carrier organic anion transporter family member. (686 aa)
F9Coagulation factor IX isoform X1. (462 aa)
LOC103079579Testisin-like. (239 aa)
ADAMTS13A disintegrin and metalloproteinase with thrombospondin motifs 13. (1522 aa)
TSPYL1Testis-specific Y-encoded-like protein 1; Belongs to the nucleosome assembly protein (NAP) family. (435 aa)
PRSS33LOW QUALITY PROTEIN: serine protease 33. (346 aa)
LOC103089778Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (350 aa)
SERPINF1Pigment epithelium-derived factor isoform X1; Belongs to the serpin family. (437 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (494 aa)
APOHBeta-2-glycoprotein 1. (345 aa)
CTRLLOW QUALITY PROTEIN: chymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family. (293 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (483 aa)
CD177LOW QUALITY PROTEIN: CD177 antigen. (449 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
C8GComplement component C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (320 aa)
HGFACHepatocyte growth factor activator. (657 aa)
MYOM3Myomesin-3. (1438 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
C1QBComplement C1q subcomponent subunit B. (252 aa)
LOC103090225Cathepsin G-like; Belongs to the peptidase S1 family. (250 aa)
CELA3BChymotrypsin-like elastase family member 3B; Belongs to the peptidase S1 family. (269 aa)
CTRCchymotrypsin-C; Belongs to the peptidase S1 family. (268 aa)
CFBComplement factor B; Belongs to the peptidase S1 family. (765 aa)
PTK7Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
LOC103079033LOW QUALITY PROTEIN: alpha-1B-glycoprotein-like. (524 aa)
LOC103073034Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
CD93Complement component C1q receptor. (649 aa)
THBDThrombomodulin. (584 aa)
SPINT1Kunitz-type protease inhibitor 1 isoform X1. (510 aa)
F5LOW QUALITY PROTEIN: coagulation factor V; Belongs to the multicopper oxidase family. (2108 aa)
AZU1Azurocidin. (252 aa)
C1QCComplement C1q subcomponent subunit C. (245 aa)
LOC103076380Complement C3-like. (1659 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa)
F13BCoagulation factor XIII B chain. (660 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (455 aa)
C9Complement component C9. (548 aa)
CELA2AChymotrypsin-like elastase family member 2A. (179 aa)
C4AComplement C4-A. (1739 aa)
SERPINA7Thyroxine-binding globulin; Belongs to the serpin family. (420 aa)
ELANELOW QUALITY PROTEIN: neutrophil elastase; Belongs to the peptidase S1 family. (267 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (197 aa)
LOC103074903Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (386 aa)
C8AComplement component C8 alpha chain. (589 aa)
PRTN3Myeloblastin; Belongs to the peptidase S1 family. (256 aa)
LOC103078577Chymotrypsinogen B-like; Belongs to the peptidase S1 family. (263 aa)
C3Complement C3. (1660 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (628 aa)
PROS1Vitamin K-dependent protein S. (674 aa)
MASP2Mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (686 aa)
PROCVitamin K-dependent protein C. (480 aa)
KLK1Kallikrein-1; Belongs to the peptidase S1 family. (261 aa)
LECT2Leukocyte cell-derived chemotaxin-2. (148 aa)
KLK6Kallikrein-6; Belongs to the peptidase S1 family. (246 aa)
C8BComplement component C8 beta chain. (586 aa)
SERPINB10Serpin B10; Belongs to the serpin family. (398 aa)
MS4A3Membrane-spanning 4-domains subfamily A member 3. (171 aa)
LOC103087584Mannose-binding protein A-like. (249 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (683 aa)
KLK12Kallikrein-12; Belongs to the peptidase S1 family. (329 aa)
SERPINB12Serpin B12; Belongs to the serpin family. (245 aa)
CTRB1Chymotrypsinogen B; Belongs to the peptidase S1 family. (263 aa)
LOC103078294Chymotrypsinogen 2-like; Belongs to the peptidase S1 family. (263 aa)
KLK14LOW QUALITY PROTEIN: kallikrein-14; Belongs to the peptidase S1 family. (301 aa)
KLK5LOW QUALITY PROTEIN: kallikrein-5; Belongs to the peptidase S1 family. (301 aa)
KLK7Kallikrein-7; Belongs to the peptidase S1 family. (252 aa)
DGKEDiacylglycerol kinase. (602 aa)
SPP2Secreted phosphoprotein 24. (213 aa)
MST1RMacrophage-stimulating protein receptor. (1382 aa)
PROZLOW QUALITY PROTEIN: vitamin K-dependent protein Z; Belongs to the peptidase S1 family. (454 aa)
LOC103082086Probable inactive serine protease 58-like. (244 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
LOC103082631Anionic trypsin-like; Belongs to the peptidase S1 family. (247 aa)
LOC103078500Small proline-rich protein 4-like. (82 aa)
LOC103083722Serpin B6-like; Belongs to the serpin family. (467 aa)
LOC103082362Cationic trypsin-like; Belongs to the peptidase S1 family. (246 aa)
F10Coagulation factor X. (509 aa)
CD59CD59 glycoprotein. (123 aa)
F7Coagulation factor VII. (387 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
AFMAfamin. (603 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
CD97CD97 antigen; Belongs to the G-protein coupled receptor 2 family. (830 aa)
ALBSerum albumin. (607 aa)
C1RLComplement C1r subcomponent-like protein; Belongs to the peptidase S1 family. (523 aa)
LOC103078895Uncharacterized protein C11orf91 homolog. (193 aa)
LOC103069153Alpha-2-macroglobulin-like. (1482 aa)
C7Complement component C7. (843 aa)
CPA1Carboxypeptidase A1. (419 aa)
LOC103091086Serine protease 46-like. (301 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
COLEC11Collectin-11 isoform X1. (267 aa)
LOC103077690Alpha-2-macroglobulin-like. (1475 aa)
C6Complement component C6. (932 aa)
MBL2LOW QUALITY PROTEIN: mannose-binding protein C. (235 aa)
C1RComplement C1r subcomponent; Belongs to the peptidase S1 family. (713 aa)
LOC103087891C4b-binding protein alpha chain-like. (665 aa)
HABP2Hyaluronan-binding protein 2. (553 aa)
C3AR1C3a anaphylatoxin chemotactic receptor; Belongs to the G-protein coupled receptor 1 family. (498 aa)
C1SLOW QUALITY PROTEIN: complement C1s subcomponent; Belongs to the peptidase S1 family. (793 aa)
CR2Complement receptor type 2 isoform X1. (1471 aa)
HPNSerine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
C4BPBC4b-binding protein beta chain. (198 aa)
CPA2LOW QUALITY PROTEIN: carboxypeptidase A2. (450 aa)
FCN1LOW QUALITY PROTEIN: ficolin (Collagen/fibrinogen domain containing) 1. (326 aa)
SERPINC1antithrombin-III; Belongs to the serpin family. (465 aa)
CD55Complement decay-accelerating factor. (571 aa)
SPINT2Kunitz-type protease inhibitor 2. (225 aa)
CPA3LOW QUALITY PROTEIN: mast cell carboxypeptidase A. (425 aa)
SPINK5LOW QUALITY PROTEIN: serine peptidase inhibitor, Kazal type 5. (875 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (250 aa)
CR1Complement receptor type 1. (161 aa)
GZMHGranzyme H; Belongs to the peptidase S1 family. (261 aa)
TFPITissue factor pathway inhibitor isoform X1. (307 aa)
SERPINB9LOW QUALITY PROTEIN: serpin peptidase inhibitor, clade B (Ovalbumin), member 9; Belongs to the serpin family. (190 aa)
TMPRSS11FLOW QUALITY PROTEIN: transmembrane protease, serine 11F; Belongs to the peptidase S1 family. (301 aa)
LOC103081213C4b-binding protein alpha chain-like. (189 aa)
FCN3LOW QUALITY PROTEIN: ficolin (Collagen/fibrinogen domain containing) 3. (282 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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