STRINGSTRING
LOC103076697 LOC103076697 RHOA RHOA CEP55 CEP55 ARL3 ARL3 CENPA CENPA CKAP2 CKAP2 LZTS2 LZTS2 SNX33 SNX33 KLHDC8A KLHDC8A SNX18 SNX18 KIF4A KIF4A CHMP1A CHMP1A SON SON CHMP2B CHMP2B CHMP3 CHMP3 LOC103085022 LOC103085022 SPTBN1 SPTBN1 LOC103076856 LOC103076856 MITD1 MITD1 CIT CIT VPS4B VPS4B ECT2 ECT2 CHMP5 CHMP5 CHMP1B CHMP1B CHMP6 CHMP6 INCENP INCENP RHOB RHOB BIRC5 BIRC5 KIF20A KIF20A CFL1 CFL1 CHMP4C CHMP4C BBS4 BBS4 NUSAP1 NUSAP1 RHOC RHOC STAMBP STAMBP MYH10 MYH10 SPTBN5 SPTBN5 CHMP7 CHMP7 CHMP2A CHMP2A JTB JTB ROCK2 ROCK2 LOC103089543 LOC103089543 CUL7 CUL7 CNTROB CNTROB USP8 USP8 RACGAP1 RACGAP1 UNC119 UNC119 TRIM36 TRIM36 SNX9 SNX9 SPAST SPAST MAP9 MAP9 ANLN ANLN KLHDC8B KLHDC8B VPS4A VPS4A RASA1 RASA1 PLK1 PLK1 PDCD6IP PDCD6IP CHMP4A CHMP4A RAB35 RAB35 APC APC LOC103082455 LOC103082455 ZFYVE26 ZFYVE26 EFHC1 EFHC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103076697Rac GTPase-activating protein 1-like. (304 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
CEP55Centrosomal protein of 55 kDa. (463 aa)
ARL3ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family. (182 aa)
CENPAHistone H3-like centromeric protein A isoform X1. (138 aa)
CKAP2Cytoskeleton-associated protein 2 isoform X1. (686 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (668 aa)
SNX33Sorting nexin. (574 aa)
KLHDC8AKelch domain-containing protein 8A. (350 aa)
SNX18Sorting nexin. (625 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1227 aa)
CHMP1ACharged multivesicular body protein 1a. (196 aa)
SONLOW QUALITY PROTEIN: protein SON. (2395 aa)
CHMP2BCharged multivesicular body protein 2b isoform X1. (213 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
LOC103085022Charged multivesicular body protein 7-like. (305 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2365 aa)
LOC103076856Cofilin-1-like; Belongs to the actin-binding proteins ADF family. (262 aa)
MITD1MIT domain-containing protein 1. (255 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1976 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (443 aa)
ECT2Protein ECT2 isoform X1. (933 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
CHMP6Charged multivesicular body protein 6. (202 aa)
INCENPInner centromere protein. (945 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
BBS4Bardet-Biedl syndrome 4 protein. (507 aa)
NUSAP1Nucleolar and spindle-associated protein 1. (445 aa)
RHOCRho-related GTP-binding protein RhoC. (193 aa)
STAMBPSTAM-binding protein isoform X2. (424 aa)
MYH10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
SPTBN5LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 5. (3370 aa)
CHMP7Charged multivesicular body protein 7-like. (450 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
JTBProtein JTB. (146 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
LOC103089543Charged multivesicular body protein 7-like. (100 aa)
CUL7Cullin-7 isoform X1; Belongs to the cullin family. (1726 aa)
CNTROBCentrobin. (904 aa)
USP8LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
RACGAP1Rac GTPase-activating protein 1. (344 aa)
UNC119Protein unc-119 homolog A. (241 aa)
TRIM36E3 ubiquitin-protein ligase TRIM36. (717 aa)
SNX9Sorting nexin-9. (680 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
MAP9Microtubule-associated protein 9-like. (643 aa)
ANLNActin-binding protein anillin. (1152 aa)
KLHDC8BKelch domain-containing protein 8B. (354 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
PDCD6IPProgrammed cell death 6-interacting protein isoform X1. (877 aa)
CHMP4ACharged multivesicular body protein 4a. (222 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
APCAdenomatous polyposis coli protein isoform X1. (2847 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ZFYVE26Zinc finger FYVE domain-containing protein 26. (2543 aa)
EFHC1EF-hand domain-containing protein 1 isoform X1. (646 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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