STRINGSTRING
GLIS1 GLIS1 CCL3 CCL3 SOX8 SOX8 GDF2 GDF2 GDF10 GDF10 HSD17B4 HSD17B4 IFT80 IFT80 HAND2 HAND2 WNT3A WNT3A TWIST1 TWIST1 SHH SHH LOC103086357 LOC103086357 AXIN2 AXIN2 SFRP1 SFRP1 MEF2D MEF2D ADAR ADAR FHL2 FHL2 BMPR1A BMPR1A CYR61 CYR61 LOC103079308 LOC103079308 CBFB CBFB LOC103082411 LOC103082411 LOC103088826 LOC103088826 BGLAP BGLAP LOC103074230 LOC103074230 RUNX2 RUNX2 SMAD5 SMAD5 EPHA2 EPHA2 WNT11 WNT11 UCMA UCMA LGR4 LGR4 JUND JUND MEN1 MEN1 LOC103073422 LOC103073422 SIRT7 SIRT7 LIMD1 LIMD1 SNAI2 SNAI2 BMPR1B BMPR1B NOG NOG FGF9 FGF9 LOC103071971 LOC103071971 HOXA2 HOXA2 BMP6 BMP6 ASF1A ASF1A CTNNB1 CTNNB1 CTHRC1 CTHRC1 MEF2C MEF2C WNT3 WNT3 LOC103070776 LOC103070776 GLI1 GLI1 SMAD1 SMAD1 JUNB JUNB BMPR2 BMPR2 SATB2 SATB2 GLI3 GLI3 ACHE ACHE HDAC4 HDAC4 FGF2 FGF2 BMP2 BMP2 MSX2 MSX2 PTH1R PTH1R WNT10B WNT10B LEF1 LEF1 LOC103076444 LOC103076444 MAPK11 MAPK11 FZD1 FZD1 LOC103081391 LOC103081391 DHH DHH NF1 NF1 DLX5 DLX5 TNN TNN TMEM119 TMEM119 LOC103076424 LOC103076424 WISP1 WISP1 LRP5 LRP5 LOC103081641 LOC103081641 LOX LOX WWOX WWOX IGFBP3 IGFBP3 MYOC MYOC FIGNL1 FIGNL1 SMAD3 SMAD3 LOC103072441 LOC103072441 LOC103088774 LOC103088774 BMP3 BMP3 SNAI1 SNAI1 IHH IHH BMP4 BMP4 SMO SMO WWTR1 WWTR1 LOC103071927 LOC103071927
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLIS1Zinc finger protein GLIS1 isoform X1. (818 aa)
CCL3LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3. (88 aa)
SOX8Transcription factor SOX-8. (463 aa)
GDF2Growth/differentiation factor 2. (431 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (440 aa)
HSD17B4Peroxisomal multifunctional enzyme type 2 isoform X1. (736 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TWIST1Twist-related protein 1 isoform X1. (204 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
LOC103086357Protein scribble homolog. (347 aa)
AXIN2Axin-2. (846 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
MEF2DMyocyte-specific enhancer factor 2D isoform X2. (511 aa)
ADARDouble-stranded RNA-specific adenosine deaminase. (1172 aa)
FHL2Four and a half LIM domains protein 2 isoform X1. (307 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CYR61Protein CYR61. (382 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
CBFBCore-binding factor subunit beta isoform X1. (187 aa)
LOC1030824111,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial-like isoform X1; Belongs to the cytochrome P450 family. (514 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (99 aa)
LOC103074230Histone chaperone ASF1A-like. (129 aa)
RUNX2Runt-related transcription factor 2 isoform X1. (550 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
UCMAUnique cartilage matrix-associated protein. (138 aa)
LGR4LOW QUALITY PROTEIN: leucine-rich repeat-containing G-protein coupled receptor 4. (950 aa)
JUNDTranscription factor jun-D. (345 aa)
MEN1Menin isoform X1. (631 aa)
LOC103073422LOW QUALITY PROTEIN: short stature homeobox protein 2-like. (359 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7. (400 aa)
LIMD1LOW QUALITY PROTEIN: LIM domain-containing protein 1. (677 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103071971Collagen alpha-1(I) chain-like. (1463 aa)
HOXA2Homeobox protein Hox-A2. (372 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
ASF1AHistone chaperone ASF1A. (204 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC103070776Histone H3-like centromeric protein CSE4-like. (277 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
JUNBTranscription factor jun-B. (347 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SATB2LOW QUALITY PROTEIN: DNA-binding protein SATB2. (734 aa)
GLI3Transcriptional activator GLI3. (1590 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (615 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1148 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
MSX2Homeobox protein MSX-2. (267 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (591 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
LOC103076444Histone H3; Belongs to the histone H3 family. (136 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
LOC103081391Histone H3.3-like. (172 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
NF1Neurofibromin isoform X1. (2841 aa)
DLX5Homeobox protein DLX-5. (289 aa)
TNNtenascin-N. (1296 aa)
TMEM119Transmembrane protein 119. (282 aa)
LOC103076424Histone H3.3-like. (136 aa)
WISP1WNT1-inducible-signaling pathway protein 1 isoform X1. (281 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1451 aa)
LOC103081641LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6-like; Belongs to the protein kinase superfamily. (394 aa)
LOXProtein-lysine 6-oxidase isoform X1. (413 aa)
WWOXWW domain-containing oxidoreductase. (36 aa)
IGFBP3Insulin-like growth factor-binding protein 3 isoform X2. (299 aa)
MYOCLOW QUALITY PROTEIN: myocilin. (480 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC103072441Tumor protein p53-inducible nuclear protein 2-like. (180 aa)
LOC103088774Tumor protein p53-inducible nuclear protein 2-like. (220 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
LOC103071927WW domain-containing oxidoreductase-like. (243 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.