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NANOG NANOG MESP1 MESP1 DUSP5 DUSP5 CTR9 CTR9 GPI GPI DUSP2 DUSP2 ETV2 ETV2 COL11A1 COL11A1 ITGAV ITGAV AXIN1 AXIN1 EXT2 EXT2 COL8A1 COL8A1 HAND1 HAND1 ARMC5 ARMC5 TBX6 TBX6 VTN VTN LEF1 LEF1 MIXL1 MIXL1 LAMB3 LAMB3 COL6A1 COL6A1 POFUT2 POFUT2 MMP9 MMP9 PAF1 PAF1 LOC103085851 LOC103085851 GATA6 GATA6 CRB2 CRB2 MMP8 MMP8 HNF1A HNF1A MAP2K1 MAP2K1 MMP14 MMP14 LOC103085466 LOC103085466 ITGB5 ITGB5 LAMA3 LAMA3 BMP7 BMP7 SMAD3 SMAD3 COL7A1 COL7A1 SNAI1 SNAI1 HMGA2 HMGA2 BMP4 BMP4 T T WNT3A WNT3A ITGB4 ITGB4 GRB2 GRB2 COL4A2 COL4A2 NODAL NODAL ITGA2 ITGA2 PRKAR1A PRKAR1A LAMB1 LAMB1 COL12A1 COL12A1 ITGB3 ITGB3 BMPR1A BMPR1A NR0B1 NR0B1 SRF SRF WNT5A WNT5A TWSG1 TWSG1 FN1 FN1 EOMES EOMES KDM6A KDM6A TLX2 TLX2 SIX2 SIX2 LOC103088826 LOC103088826 TBX19 TBX19 EYA1 EYA1 MMP2 MMP2 NF2 NF2 EPHA2 EPHA2 WNT11 WNT11 TAF10 TAF10 RTF1 RTF1 ITGA8 ITGA8 ITGA4 ITGA4 SOX17 SOX17 LHX1 LHX1 NOG NOG TAL1 TAL1 SCXB SCXB ITGA3 ITGA3 MSGN1 MSGN1 CTNNB1 CTNNB1 DUSP1 DUSP1 EXOC4 EXOC4 SFRP2 SFRP2 ATOH8 ATOH8 SOX7 SOX7 WNT3 WNT3 HOXA11 HOXA11 INHBA INHBA PRKACA PRKACA SMAD1 SMAD1 ITGA7 ITGA7 ITGA5 ITGA5 EPB41L5 EPB41L5 BMPR2 BMPR2 FOXF1 FOXF1 LOC103076784 LOC103076784 MMP15 MMP15 LEO1 LEO1 MESP2 MESP2 SETD2 SETD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NANOGHomeobox protein NANOG. (306 aa)
MESP1Mesoderm posterior protein 1. (267 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
CTR9RNA polymerase-associated protein CTR9 homolog. (1176 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (311 aa)
ETV2LOW QUALITY PROTEIN: ETS translocation variant 2. (333 aa)
COL11A1Collagen alpha-1(XI) chain-like isoform X1. (1824 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
AXIN1Axin-1. (866 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (718 aa)
COL8A1Collagen alpha-1(VIII) chain isoform X1. (745 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
ARMC5Armadillo repeat-containing protein 5. (942 aa)
TBX6T-box transcription factor TBX6. (436 aa)
VTNVitronectin isoform X1. (565 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
MIXL1Homeobox protein MIXL1. (237 aa)
LAMB3Laminin subunit beta-3. (1172 aa)
COL6A1Collagen alpha-1(VI) chain. (1150 aa)
POFUT2GDP-fucose protein O-fucosyltransferase 2. (387 aa)
MMP9Matrix metalloproteinase-9. (708 aa)
PAF1RNA polymerase II-associated factor 1 homolog isoform X1. (526 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
CRB2Protein crumbs homolog 2. (1281 aa)
MMP8Neutrophil collagenase. (468 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (632 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
MMP14Matrix metalloproteinase-14 isoform X2. (582 aa)
LOC103085466Band 4.1-like protein 5-like. (256 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LAMA3Laminin subunit alpha-3. (3338 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
COL7A1Collagen alpha-1(VII) chain. (2986 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
TBrachyury protein isoform X1. (435 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ITGB4Integrin beta. (1754 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
COL4A2Collagen alpha-2(IV) chain. (1671 aa)
NODALNodal homolog. (349 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
COL12A1Collagen alpha-1(XII) chain. (3120 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
SRFSerum response factor. (510 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TWSG1Twisted gastrulation protein homolog 1. (222 aa)
FN1LOW QUALITY PROTEIN: fibronectin. (2483 aa)
EOMESEomesodermin homolog isoform X1. (694 aa)
KDM6ALysine-specific demethylase 6A-like isoform X1. (1455 aa)
TLX2T-cell leukemia homeobox protein 2. (284 aa)
SIX2Homeobox protein SIX2. (296 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
TBX19T-box transcription factor TBX19. (444 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (594 aa)
MMP272 kDa type IV collagenase. (584 aa)
NF2LOW QUALITY PROTEIN: merlin. (592 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
RTF1RNA polymerase-associated protein RTF1 homolog. (710 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
SOX17Transcription factor SOX-17. (405 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TAL1T-cell acute lymphocytic leukemia protein 1. (318 aa)
SCXBBasic helix-loop-helix transcription factor scleraxis. (203 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
MSGN1Mesogenin-1. (188 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
EXOC4Exocyst complex component 4 isoform X1. (975 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
ATOH8Protein atonal homolog 8. (317 aa)
SOX7Transcription factor SOX-7. (392 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
HOXA11Homeobox protein Hox-A11. (317 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
EPB41L5LOW QUALITY PROTEIN: band 4.1-like protein 5. (505 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
FOXF1Forkhead box protein F1. (377 aa)
LOC103076784Glucose-6-phosphate isomerase; Belongs to the GPI family. (821 aa)
MMP15Matrix metalloproteinase-15. (677 aa)
LEO1RNA polymerase-associated protein LEO1 isoform X1. (666 aa)
MESP2Mesoderm posterior protein 2. (366 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2562 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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