STRINGSTRING
FGF2 FGF2 AGTR1 AGTR1 BMP4 BMP4 LOC103091514 LOC103091514 STAT5A STAT5A STAT3 STAT3 PPP1R16B PPP1R16B PROK1 PROK1 FGFBP1 FGFBP1 CAV2 CAV2 VEGFC VEGFC PROX1 PROX1 NF1 NF1 KDR KDR ACVRL1 ACVRL1 EGR3 EGR3 CDH13 CDH13 PIK3CD PIK3CD VASH2 VASH2 NR4A1 NR4A1 PRKCA PRKCA FGF7 FGF7 GDF2 GDF2 APLNR APLNR PDPK1 PDPK1 PDGFB PDGFB PLXNB3 PLXNB3 HMOX1 HMOX1 ITGB3 ITGB3 CCL11 CCL11 WNT5A WNT5A SIRT1 SIRT1 VIP VIP NRARP NRARP VEGFA VEGFA PRKD2 PRKD2 EGFL7 EGFL7 SCG2 SCG2 TGFBR1 TGFBR1 FGF10 FGF10 PGF PGF JUN JUN LRG1 LRG1 AKT3 AKT3 HTR2B HTR2B LOC103075090 LOC103075090 SIRT6 SIRT6 VEGFB VEGFB ITGA4 ITGA4 NRAS NRAS EGF EGF EMC10 EMC10 ECM1 ECM1 BMP6 BMP6 FLT4 FLT4 PDCL3 PDCL3 CCL24 CCL24 BMPR2 BMPR2 ZNF580 ZNF580 CCL26 CCL26 LOC103073179 LOC103073179 CCR3 CCR3 F3 F3 BMP2 BMP2 FGFR1 FGFR1 PRKD1 PRKD1 PDCD6 PDCD6 KIAA1462 KIAA1462 AGGF1 AGGF1 THBS4 THBS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
LOC103091514Phosducin-like protein 3-like. (237 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT3Signal transducer and activator of transcription. (654 aa)
PPP1R16BProtein phosphatase 1 regulatory inhibitor subunit 16B isoform X2. (568 aa)
PROK1LOW QUALITY PROTEIN: prokineticin-1. (130 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (237 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
PROX1Prospero homeobox protein 1. (737 aa)
NF1Neurofibromin isoform X1. (2841 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
VASH2Vasohibin-2 isoform X1. (355 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1 isoform X1. (598 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GDF2Growth/differentiation factor 2. (431 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PLXNB3plexin-B3. (1906 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
CCL11C-C motif chemokine. (99 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SIRT1LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa)
VIPVIP peptides isoform X1. (170 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (852 aa)
EGFL7Epidermal growth factor-like protein 7. (274 aa)
SCG2Secretogranin-2. (616 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HTR2B5-hydroxytryptamine receptor 2B. (537 aa)
LOC103075090UPF0556 protein C19orf10 homolog. (167 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (359 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
NRASGTPase NRas. (189 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (260 aa)
ECM1Extracellular matrix protein 1 isoform X1. (578 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
PDCL3Phosducin-like protein 3. (129 aa)
CCL24c-C motif chemokine 24. (130 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ZNF580Zinc finger protein 580. (172 aa)
CCL26c-C motif chemokine 26. (94 aa)
LOC103073179Phosducin-like protein 3-like. (122 aa)
CCR3c-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
FGFR1Fibroblast growth factor receptor. (837 aa)
PRKD1Serine/threonine-protein kinase D1-like. (801 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
KIAA1462Junctional protein associated with coronary artery disease homolog. (1285 aa)
AGGF1Angiogenic factor with G patch and FHA domains 1-like. (714 aa)
THBS4Thrombospondin-4. (961 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.