STRINGSTRING
CAV1 CAV1 BMP4 BMP4 ENAM ENAM NKX3-2 NKX3-2 LOC103070587 LOC103070587 SRC SRC DLL1 DLL1 KLF5 KLF5 B9D1 B9D1 SAV1 SAV1 BMP7 BMP7 YAP1 YAP1 SIDT2 SIDT2 LOC103087231 LOC103087231 BCCIP BCCIP BHLHA15 BHLHA15 RARG RARG GATA6 GATA6 LOC103085851 LOC103085851 WDR77 WDR77 PROX1 PROX1 JAG1 JAG1 DSPP DSPP C1GALT1 C1GALT1 ABL1 ABL1 EMX1 EMX1 EXT1 EXT1 ASCL1 ASCL1 SOX9 SOX9 LOC103070818 LOC103070818 NKX2-2 NKX2-2 RFX6 RFX6 SOX4 SOX4 CDH2 CDH2 AGPAT6 AGPAT6 PDPK1 PDPK1 SLC9A4 SLC9A4 MAP1B MAP1B ROS1 ROS1 NR5A2 NR5A2 NKX6-3 NKX6-3 WNT5A WNT5A HES1 HES1 FST FST TP63 TP63 PAX6 PAX6 SPDEF SPDEF TGFB1 TGFB1 LHX3 LHX3 NOTCH1 NOTCH1 WNT11 WNT11 CDK6 CDK6 ONECUT1 ONECUT1 GATA5 GATA5 RBM4 RBM4 NEUROD1 NEUROD1 FZD5 FZD5 TMEM231 TMEM231 DLG5 DLG5 FASN FASN HNF4A HNF4A AGR2 AGR2 RARB RARB RARA RARA POU3F2 POU3F2 BMP6 BMP6 CTNNB1 CTNNB1 NFIB NFIB PRDM1 PRDM1 FOXA1 FOXA1 DLX3 DLX3 GDF11 GDF11 HOXA5 HOXA5 LOC103077691 LOC103077691 FGF2 FGF2 YIPF6 YIPF6 CLCN2 CLCN2 VAX1 VAX1 BMP2 BMP2 IL6ST IL6ST NKX6-1 NKX6-1 FGF8 FGF8 GATA4 GATA4 SMO SMO PAX4 PAX4 HIF1A HIF1A CDX2 CDX2 VHL VHL BMP5 BMP5 LOC103078457 LOC103078457 PDX1 PDX1 LOC103086063 LOC103086063 IL31RA IL31RA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
ENAMEnamelin. (1146 aa)
NKX3-2Homeobox protein Nkx-3.2. (327 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
SRCTyrosine-protein kinase. (548 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
KLF5Krueppel-like factor 5 isoform X1. (454 aa)
B9D1B9 domain-containing protein 1. (204 aa)
SAV1Protein salvador homolog 1. (384 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
YAP1Yorkie homolog. (430 aa)
SIDT2SID1 transmembrane family member 2. (835 aa)
LOC103087231Yorkie homolog isoform X1. (489 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (308 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (185 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
PROX1Prospero homeobox protein 1. (737 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
DSPPDentin sialophosphoprotein. (1110 aa)
C1GALT1glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1. (376 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
EMX1Homeobox protein EMX1. (288 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (750 aa)
ASCL1Achaete-scute homolog 1. (227 aa)
SOX9Transcription factor SOX-9 isoform X1. (509 aa)
LOC103070818Homeobox protein Nkx-6.1-like. (448 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
RFX6DNA-binding protein RFX6. (923 aa)
SOX4Transcription factor SOX. (306 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
AGPAT6Glycerol-3-phosphate acyltransferase 4. (456 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
MAP1BMicrotubule-associated protein 1B. (2474 aa)
ROS1Tyrosine-protein kinase receptor. (2348 aa)
NR5A2LOW QUALITY PROTEIN: nuclear receptor subfamily 5 group A member 2. (541 aa)
NKX6-3Homeobox protein Nkx-6.3. (257 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HES1Transcription factor HES-1. (280 aa)
FSTFollistatin isoform X1. (344 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
SPDEFSAM pointed domain-containing Ets transcription factor isoform X1. (337 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
LHX3LIM/homeobox protein Lhx3 isoform X1. (403 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ONECUT1One cut domain family member. (464 aa)
GATA5Transcription factor GATA-5. (407 aa)
RBM4RNA-binding protein 4 isoform X1. (363 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
TMEM231Transmembrane protein 231. (316 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
FASNFatty acid synthase. (2515 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (474 aa)
AGR2Anterior gradient protein 2 homolog isoform X1. (175 aa)
RARBRetinoic acid receptor beta isoform X1. (458 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
POU3F2POU domain protein. (439 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (576 aa)
PRDM1PR domain zinc finger protein 1 isoform X1. (826 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
DLX3Homeobox protein DLX-3. (287 aa)
GDF11Growth/differentiation factor 11. (404 aa)
HOXA5Homeobox protein Hox-A5. (270 aa)
LOC103077691Fructose-2,6-bisphosphatase TIGAR. (269 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
YIPF6Protein YIPF. (236 aa)
CLCN2Chloride channel protein 2 isoform X1. (904 aa)
VAX1Ventral anterior homeobox 1. (332 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
NKX6-1Homeobox protein Nkx-6.1-like. (365 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GATA4Transcription factor GATA-4. (435 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
PAX4LOW QUALITY PROTEIN: paired box 4. (478 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
CDX2Homeobox protein CDX-2. (303 aa)
VHLLOW QUALITY PROTEIN: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase. (219 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
LOC103078457Homeobox protein orthopedia-like. (331 aa)
PDX1Pancreas/duodenum homeobox protein 1. (286 aa)
LOC103086063Homeobox protein orthopedia-like. (267 aa)
IL31RALOW QUALITY PROTEIN: interleukin 31 receptor A. (268 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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