17 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103085514	Fragile X mental retardation protein 1-like. (236 aa)
	SYK	Tyrosine-protein kinase SYK isoform X1. (636 aa)
	FMR1	Fragile X mental retardation protein 1 homolog isoform X1. (632 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	SCYL2	SCY1-like protein 2. (929 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
	GREM1	Gremlin. (184 aa)
	INSR	Tyrosine-protein kinase receptor. (1382 aa)
	ARRB2	Beta-arrestin-2 isoform X1. (421 aa)
	AHI1	Jouberin. (1245 aa)
	LOC103076176	ATPase family AAA domain-containing protein 1-like. (84 aa)
	PICK1	PRKCA-binding protein isoform X1. (417 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
	SFRP4	Secreted frizzled-related protein 4. (346 aa)
	ARRB1	Beta-arrestin-1. (418 aa)
	PCSK9	LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9. (659 aa)
	ATAD1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (404 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	ARRB2	A0A340X532	A0A340XCH2	Beta-arrestin-1.	Beta-arrestin-2 isoform X1.	0.935
ARRB2	ARRB1	A0A340XCH2	A0A340X532	Beta-arrestin-2 isoform X1.	Beta-arrestin-1.	0.935
ARRB2	PICK1	A0A340XCH2	A0A340WXL1	Beta-arrestin-2 isoform X1.	PRKCA-binding protein isoform X1.	0.439
ATAD1	PICK1	A0A340YFY1	A0A340WXL1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family.	PRKCA-binding protein isoform X1.	0.436
EGF	INSR	A0A340XVB5	A0A340XGU4	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.939
EGF	PCSK9	A0A340XVB5	A0A340YIE0	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9.	0.887
EGF	PLCG2	A0A340XVB5	A0A340WY66	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.437
EGF	WNT3A	A0A340XVB5	A0A340X5F1	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.531
INSR	EGF	A0A340XGU4	A0A340XVB5	Tyrosine-protein kinase receptor.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.939
LOC103076176	PICK1	A0A340WWM6	A0A340WXL1	ATPase family AAA domain-containing protein 1-like.	PRKCA-binding protein isoform X1.	0.436
PCSK9	EGF	A0A340YIE0	A0A340XVB5	LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.887
PICK1	ARRB2	A0A340WXL1	A0A340XCH2	PRKCA-binding protein isoform X1.	Beta-arrestin-2 isoform X1.	0.439
PICK1	ATAD1	A0A340WXL1	A0A340YFY1	PRKCA-binding protein isoform X1.	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family.	0.436
PICK1	LOC103076176	A0A340WXL1	A0A340WWM6	PRKCA-binding protein isoform X1.	ATPase family AAA domain-containing protein 1-like.	0.436
PLCG2	EGF	A0A340WY66	A0A340XVB5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.437
PLCG2	SYK	A0A340WY66	A0A340WDP8	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Tyrosine-protein kinase SYK isoform X1.	0.995
SFRP4	WNT3A	A0A340X1D6	A0A340X5F1	Secreted frizzled-related protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.867
SYK	PLCG2	A0A340WDP8	A0A340WY66	Tyrosine-protein kinase SYK isoform X1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.995
WNT3A	EGF	A0A340X5F1	A0A340XVB5	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.531
WNT3A	SFRP4	A0A340X5F1	A0A340X1D6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 4.	0.867