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| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa) |
| | HCK | Tyrosine-protein kinase. (504 aa) |
| | MYO1G | Unconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | LOC103070587 | Tyrosine-protein kinase ABL1-like. (126 aa) |
| | SYK | Tyrosine-protein kinase SYK isoform X1. (636 aa) |
| | SRC | Tyrosine-protein kinase. (548 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (749 aa) |
| | CCR6 | c-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | IGJ | Immunoglobulin J chain. (158 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | MARCH8 | E3 ubiquitin-protein ligase MARCH8 isoform X1. (573 aa) |
| | LAX1 | LOW QUALITY PROTEIN: lymphocyte transmembrane adapter 1. (430 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5. (280 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | STAT3 | Signal transducer and activator of transcription. (654 aa) |
| | IL6 | LOW QUALITY PROTEIN: interleukin-6. (243 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain. (278 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (312 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | BCL6 | B-cell lymphoma 6 protein isoform X1. (728 aa) |
| | TEC | Tyrosine-protein kinase. (633 aa) |
| | LOC103076960 | Butyrophilin subfamily 3 member A2-like. (144 aa) |
| | LOC103083828 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | ABL2 | Tyrosine-protein kinase. (1067 aa) |
| | FGA | Fibrinogen alpha chain. (605 aa) |
| | ARG2 | Arginase. (354 aa) |
| | LOC103086796 | SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family. (255 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | FGB | Fibrinogen beta chain isoform X1. (488 aa) |
| | TRAF3IP2 | Adapter protein CIKS isoform X1. (565 aa) |
| | LOC103084935 | T-cell receptor-associated transmembrane adapter 1-like. (218 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | IL21R | Interleukin-21 receptor. (540 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | LOC103088795 | TNF receptor-associated factor 6-like. (315 aa) |
| | FOXP3 | Forkhead box protein P3 isoform X1. (431 aa) |
| | TXK | Tyrosine-protein kinase. (525 aa) |
| | C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa) |
| | ABL1 | Tyrosine-protein kinase. (1006 aa) |
| | C5 | LOW QUALITY PROTEIN: complement C5. (1677 aa) |
| | IL17A | interleukin-17A-like. (153 aa) |
| | AIRE | Autoimmune regulator. (562 aa) |
| | TNFRSF21 | Tumor necrosis factor receptor superfamily member 21. (652 aa) |
| | LOC103087452 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (269 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (399 aa) |
| | ATAD5 | LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 5. (1898 aa) |
| | LOC103090661 | Interferon alpha-1-like. (189 aa) |
| | FRK | Tyrosine-protein kinase. (513 aa) |
| | PRF1 | Perforin-1. (555 aa) |
| | CD19 | B-lymphocyte antigen CD19. (568 aa) |
| | SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) |
| | IFNE | Interferon epsilon. (193 aa) |
| | LOC103069739 | Interferon alpha-1-like. (189 aa) |
| | IL4R | Interleukin-4 receptor subunit alpha isoform X2. (832 aa) |
| | IL9R | Interleukin-9 receptor-like. (606 aa) |
| | TSC1 | Hamartin isoform X1. (1170 aa) |
| | CSF2RB | Cytokine receptor common subunit beta. (896 aa) |
| | LOC103089778 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (350 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (480 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (197 aa) |
| | LOC103075361 | Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa) |
| | LOC103068617 | Interferon alpha-1-like. (188 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain isoform X1. (171 aa) |
| | UNC13D | Protein unc-13 homolog D. (1090 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | CD79B | B-cell antigen receptor complex-associated protein beta chain isoform X1. (230 aa) |
| | LOC103091202 | Interferon alpha-1-like. (188 aa) |
| | LOC103069181 | Interferon alpha-1-like. (189 aa) |
| | LOC103073219 | LOW QUALITY PROTEIN: interferon alpha-8-like. (248 aa) |
| | LOC103073772 | Interferon beta-2-like. (186 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10. (233 aa) |
| | LOC103075075 | Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha. (499 aa) |
| | CD247 | T-cell surface glycoprotein CD3 zeta chain. (152 aa) |
| | TREM1 | LOW QUALITY PROTEIN: triggering receptor expressed on myeloid cells 1. (254 aa) |
| | IFNK | Interferon kappa. (207 aa) |
| | EXOSC3 | Exosome complex component RRP40. (275 aa) |
| | CD79A | B-cell antigen receptor complex-associated protein alpha chain isoform X1. (223 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain. (182 aa) |
| | CARD9 | Caspase recruitment domain-containing protein 9. (539 aa) |
| | IL18R1 | Interleukin-18 receptor 1. (538 aa) |
| | C1QA | Complement C1q subcomponent subunit A. (245 aa) |
| | C1QB | Complement C1q subcomponent subunit B. (252 aa) |
| | SEMA4A | semaphorin-4A; Belongs to the semaphorin family. (762 aa) |
| | CTSC | Dipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (463 aa) |
| | LOC103087567 | HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (253 aa) |
| | CTSH | Pro-cathepsin H isoform X1; Belongs to the peptidase C1 family. (335 aa) |
| | TNFRSF11A | Tumor necrosis factor receptor superfamily member 11A. (850 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | RORA | LOW QUALITY PROTEIN: nuclear receptor ROR-alpha. (527 aa) |
| | YES1 | Tyrosine-protein kinase. (541 aa) |
| | LOC103075733 | Adenine deaminase-like. (315 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (290 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | LOC103076380 | Complement C3-like. (1659 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (454 aa) |
| | LOC103085172 | HLA class II histocompatibility antigen, DM beta chain-like. (282 aa) |
| | LOC103087297 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like. (266 aa) |
| | C2 | Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1 isoform X1. (294 aa) |
| | RELB | Transcription factor RelB. (564 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | C9 | Complement component C9. (548 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1. (2536 aa) |
| | FGR | Tyrosine-protein kinase. (537 aa) |
| | CTSS | Cathepsin S isoform X1; Belongs to the peptidase C1 family. (340 aa) |
| | C4A | Complement C4-A. (1739 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha. (459 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | LOC103085441 | HLA class II histocompatibility antigen, DM alpha chain-like; Belongs to the MHC class II family. (261 aa) |
| | FGL1 | Fibrinogen-like protein 1 isoform X1. (315 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | SLAMF6 | SLAM family member 6. (321 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | LOC103074903 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (386 aa) |
| | LOC103088028 | Granzyme M-like; Belongs to the peptidase S1 family. (167 aa) |
| | C8A | Complement component C8 alpha chain. (589 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | MATK | Tyrosine-protein kinase. (485 aa) |
| | EXO1 | Exonuclease 1. (835 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | TNFSF13B | Tumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family. (283 aa) |
| | TYK2 | Tyrosine-protein kinase. (1186 aa) |
| | LOC103078393 | Granzyme M-like; Belongs to the peptidase S1 family. (257 aa) |
| | TAP1 | LOW QUALITY PROTEIN: antigen peptide transporter 1. (770 aa) |
| | LOC103086000 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | LOC103078858 | Adenine deaminase-like. (322 aa) |
| | C3 | Complement C3. (1660 aa) |
| | LOC103083691 | HLA class II histocompatibility antigen, DO beta chain-like isoform X1. (259 aa) |
| | TAP2 | LOW QUALITY PROTEIN: antigen peptide transporter 2. (746 aa) |
| | MASP2 | Mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (686 aa) |
| | C8B | Complement component C8 beta chain. (586 aa) |
| | CD7 | T-cell antigen CD7. (205 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | ADA | Adenosine deaminase. (363 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) |
| | LYN | Tyrosine-protein kinase. (516 aa) |
| | EXOSC6 | Exosome complex component MTR3. (218 aa) |
| | IL18BP | Interleukin-18-binding protein. (192 aa) |
| | KIAA1841 | LOW QUALITY PROTEIN: uncharacterized protein KIAA1841 homolog. (706 aa) |
| | DBNL | Drebrin-like protein isoform X1. (438 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | HLX | H2.0-like homeobox protein. (483 aa) |
| | LOC103088508 | TNF receptor-associated factor 6-like. (251 aa) |
| | TBX21 | T-box transcription factor TBX21. (535 aa) |
| | LOC103088679 | G-protein coupled receptor 183-like; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C isoform X1. (483 aa) |
| | PHB | Prohibitin. (297 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa) |
| | RAB44 | Ras-related protein Rab-44. (931 aa) |
| | AKIRIN2 | Akirin-2. (319 aa) |
| | CD8A | T-cell surface glycoprotein CD8 alpha chain. (239 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IRF7 | Interferon regulatory factor 7. (486 aa) |
| | CX3CR1 | CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | CD81 | Tetraspanin. (201 aa) |
| | BACH2 | Transcription regulator protein BACH2. (839 aa) |
| | LAIR1 | Leukocyte-associated immunoglobulin-like receptor 1. (254 aa) |
| | BMX | Tyrosine-protein kinase. (651 aa) |
| | EPHB6 | Ephrin type-B receptor 6. (1011 aa) |
| | ZP3 | Zona pellucida sperm-binding protein 3. (421 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | ERAP2 | Aminopeptidase. (952 aa) |
| | LOC103087963 | Uncharacterized protein LOC103087963. (275 aa) |
| | LOC103074825 | CD166 antigen-like isoform X1. (583 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (87 aa) |
| | DEF6 | Differentially expressed in FDCP 6 homolog. (631 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | CD4 | T-cell surface glycoprotein CD4. (454 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | C7 | Complement component C7. (843 aa) |
| | MORN5 | MORN repeat-containing protein 5. (172 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit isoform X1. (899 aa) |
| | KLHL6 | Kelch-like protein 6. (621 aa) |
| | C6 | Complement component C6. (932 aa) |
| | MBL2 | LOW QUALITY PROTEIN: mannose-binding protein C. (235 aa) |
| | LCK | Tyrosine-protein kinase. (520 aa) |
| | C1R | Complement C1r subcomponent; Belongs to the peptidase S1 family. (713 aa) |
| | LOC103087891 | C4b-binding protein alpha chain-like. (665 aa) |
| | ZAP70 | Tyrosine-protein kinase. (635 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | C1S | LOW QUALITY PROTEIN: complement C1s subcomponent; Belongs to the peptidase S1 family. (793 aa) |
| | EFCAB4B | EF-hand calcium-binding domain-containing protein 4B isoform X1. (721 aa) |
| | AICDA | Single-stranded DNA cytosine deaminase. (208 aa) |
| | RFTN1 | Raftlin. (564 aa) |
| | C4BPB | C4b-binding protein beta chain. (198 aa) |
| | FCAMR | LOW QUALITY PROTEIN: high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor. (549 aa) |
| | CD55 | Complement decay-accelerating factor. (571 aa) |
| | SWAP70 | Switch-associated protein 70 isoform X1. (585 aa) |
| | BLK | Tyrosine-protein kinase. (501 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | BTN3A3 | Butyrophilin subfamily 3 member A3. (630 aa) |
| | IRF4 | LOW QUALITY PROTEIN: interferon regulatory factor 4. (454 aa) |
| | CD160 | LOW QUALITY PROTEIN: CD160 molecule. (177 aa) |
| | TREX1 | LOW QUALITY PROTEIN: three prime repair exonuclease 1. (368 aa) |
