STRINGSTRING
LOC103070679 LOC103070679 RHOA RHOA EDN2 EDN2 AGTR1 AGTR1 ADRA1D ADRA1D FGFBP3 FGFBP3 C2CD4A C2CD4A AVPR1B AVPR1B SLC27A4 SLC27A4 ACTA2 ACTA2 HTR1D HTR1D CPS1 CPS1 EDNRA EDNRA KCNA5 KCNA5 DOCK4 DOCK4 ADRA2A ADRA2A UCN UCN SLC5A6 SLC5A6 PRKG1 PRKG1 ADRA2B ADRA2B ADRB1 ADRB1 GCLM GCLM LOC103072349 LOC103072349 LOC103069138 LOC103069138 PLOD3 PLOD3 BMPR2 BMPR2 ABCC1 ABCC1 TJP2 TJP2 ADRA1A ADRA1A INS INS EDNRB EDNRB HRH2 HRH2 GPER1 GPER1 SH3GL2 SH3GL2 LOC103081266 LOC103081266 SLIT2 SLIT2 LOC103078300 LOC103078300 ADRA1B ADRA1B BMP6 BMP6 ATG5 ATG5 DRD1 DRD1 HTR7 HTR7 TRPM4 TRPM4 AVP AVP NPPA NPPA SCPEP1 SCPEP1 PTP4A3 PTP4A3 PLEC PLEC AGTR2 AGTR2 F2R F2R GRIP2 GRIP2 COMP COMP KLF2 KLF2 SLC1A3 SLC1A3 HTR2B HTR2B ADORA2B ADORA2B TJP3 TJP3 SLC27A1 SLC27A1 UTS2R UTS2R CLDN5 CLDN5 ATP1A2 ATP1A2 FABP5 FABP5 TBXA2R TBXA2R F2RL1 F2RL1 BBS2 BBS2 PLVAP PLVAP DOCK5 DOCK5 GCLC GCLC C2CD4C C2CD4C LOC103087835 LOC103087835 AGER AGER OCLN OCLN ACTG2 ACTG2 HTR1B HTR1B GPR4 GPR4 ARHGAP35 ARHGAP35 ADRA2C ADRA2C NOS1 NOS1 SMTNL1 SMTNL1 VAMP2 VAMP2 CDH5 CDH5 DDAH1 DDAH1 ITGB1BP1 ITGB1BP1 AVPR2 AVPR2 P2RX1 P2RX1 SERPINF2 SERPINF2 LOC103074046 LOC103074046 PTPRJ PTPRJ EXT2 EXT2 UTS2 UTS2 MFSD2A MFSD2A SLC1A1 SLC1A1 CTNNBIP1 CTNNBIP1 SLC2A1 SLC2A1 EXT1 EXT1 DBH DBH CAV1 CAV1 KNG1 KNG1 LOC103068503 LOC103068503 LOC103090553 LOC103090553 ADCY6 ADCY6 MYLK3 MYLK3 ASIC2 ASIC2 RAMP2 RAMP2 SLC16A2 SLC16A2 FGB FGB SCNN1B SCNN1B CBS CBS BCR BCR LOC103074576 LOC103074576 ATP2B1 ATP2B1 P2RX4 P2RX4 LOC103082455 LOC103082455 AGT AGT P2RY2 P2RY2 ADRB3 ADRB3 LOC103087333 LOC103087333 MKKS MKKS PDE2A PDE2A BDKRB1 BDKRB1 EDN3 EDN3 SNTA1 SNTA1 VSTM4 VSTM4 ADRB2 ADRB2 EDN1 EDN1 TRPV4 TRPV4 HTR1A HTR1A FERMT2 FERMT2 LOC103085748 LOC103085748 ARHGAP42 ARHGAP42 BDKRB2 BDKRB2 SLC1A2 SLC1A2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC103070679Cysteine synthase-like. (284 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
EDN2Endothelin-2. (180 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
FGFBP3Fibroblast growth factor-binding protein 3. (255 aa)
C2CD4ALOW QUALITY PROTEIN: C2 calcium-dependent domain containing 4A. (375 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
SLC27A4Long-chain fatty acid transport protein 4. (643 aa)
ACTA2Actin, aortic smooth muscle isoform X1. (377 aa)
HTR1DLOW QUALITY PROTEIN: 5-hydroxytryptamine (Serotonin) receptor 1D, G protein-coupled. (377 aa)
CPS1Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1505 aa)
EDNRAEndothelin-1 receptor isoform X2. (318 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (595 aa)
DOCK4LOW QUALITY PROTEIN: dedicator of cytokinesis protein 4; Belongs to the DOCK family. (2004 aa)
ADRA2Aalpha-2A adrenergic receptor. (462 aa)
UCNUrocortin. (126 aa)
SLC5A6Sodium-dependent multivitamin transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (638 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
ADRA2Balpha-2B adrenergic receptor. (440 aa)
ADRB1Beta-1 adrenergic receptor. (465 aa)
GCLMGlutamate--cysteine ligase regulatory subunit. (258 aa)
LOC103072349Calcium-activated potassium channel subunit alpha-1-like. (1073 aa)
LOC103069138Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (739 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ABCC1Multidrug resistance-associated protein 1. (1543 aa)
TJP2Tight junction protein ZO-2 isoform X1; Belongs to the MAGUK family. (1186 aa)
ADRA1Aalpha-1A adrenergic receptor. (467 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
EDNRBEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
SH3GL2endophilin-A1. (352 aa)
LOC103081266Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
SLIT2LOW QUALITY PROTEIN: slit homolog 2 protein. (1521 aa)
LOC103078300Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)
ADRA1Balpha-1B adrenergic receptor. (519 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
HTR75-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (448 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
NPPANatriuretic peptides A. (152 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (448 aa)
PTP4A3Protein tyrosine phosphatase type IVA 3 isoform X1. (173 aa)
PLECPlectin. (4678 aa)
AGTR2Type-2 angiotensin II receptor-like; Belongs to the G-protein coupled receptor 1 family. (363 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
GRIP2Glutamate receptor-interacting protein 2. (1042 aa)
COMPCartilage oligomeric matrix protein isoform X1. (756 aa)
KLF2Krueppel-like factor 2. (355 aa)
SLC1A3Amino acid transporter. (542 aa)
HTR2B5-hydroxytryptamine receptor 2B. (537 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
TJP3Tight junction protein ZO-3 isoform X1; Belongs to the MAGUK family. (927 aa)
SLC27A1Long-chain fatty acid transport protein 1. (646 aa)
UTS2RUrotensin-2 receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
FABP5Fatty acid-binding protein, epidermal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
F2RL1Proteinase-activated receptor 2. (397 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
PLVAPPlasmalemma vesicle-associated protein. (440 aa)
DOCK5Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (1772 aa)
GCLCGlutamate--cysteine ligase catalytic subunit isoform X1. (637 aa)
C2CD4CC2 calcium-dependent domain-containing protein 4C. (420 aa)
LOC103087835C2 calcium-dependent domain-containing protein 4A-like. (373 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (421 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (527 aa)
ACTG2Actin, gamma-enteric smooth muscle isoform X1. (376 aa)
HTR1B5-hydroxytryptamine receptor 1B. (399 aa)
GPR4G-protein coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (381 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
ADRA2Calpha-2C adrenergic receptor. (682 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1427 aa)
SMTNL1Smoothelin-like protein 1. (482 aa)
VAMP2Vesicle-associated membrane protein 2. (116 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
DDAH1N(G),N(G)-dimethylarginine dimethylaminohydrolase 1. (185 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (494 aa)
LOC103074046Acid-sensing ion channel 2-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (232 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1155 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (718 aa)
UTS2Urotensin-2. (124 aa)
MFSD2AMajor facilitator superfamily domain-containing protein 2A isoform X1. (529 aa)
SLC1A1Amino acid transporter. (524 aa)
CTNNBIP1Beta-catenin-interacting protein 1 isoform X1. (81 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (750 aa)
DBHDopamine beta-hydroxylase. (608 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
KNG1Kininogen-1 isoform X1. (627 aa)
LOC103068503LOW QUALITY PROTEIN: fibrinogen gamma-B chain-like. (445 aa)
LOC103090553Tight junction protein ZO-1-like; Belongs to the MAGUK family. (2139 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
ASIC2Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (327 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
SLC16A2Monocarboxylate transporter 8. (404 aa)
FGBFibrinogen beta chain isoform X1. (488 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (477 aa)
BCRBreakpoint cluster region protein isoform X2. (1272 aa)
LOC103074576Smoothelin-like protein 2-like. (456 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
P2RY2P2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
ADRB3LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (375 aa)
LOC103087333Amino acid transporter. (430 aa)
MKKSmcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
PDE2APhosphodiesterase. (941 aa)
BDKRB1B1 bradykinin receptor. (352 aa)
EDN3Endothelin-3. (211 aa)
SNTA1Alpha-1-syntrophin isoform X1. (505 aa)
VSTM4V-set and transmembrane domain-containing protein 4. (317 aa)
ADRB2Beta-2 adrenergic receptor. (419 aa)
EDN1Endothelin-1. (202 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
FERMT2Fermitin family homolog 2 isoform X1. (687 aa)
LOC103085748Acid-sensing ion channel 2-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (331 aa)
ARHGAP42Rho GTPase-activating protein 42-like. (874 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (379 aa)
SLC1A2Amino acid transporter. (565 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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