STRINGSTRING
FHL2 FHL2 DNAH11 DNAH11 ENG ENG GPR126 GPR126 PARVA PARVA HIF1A HIF1A CHD7 CHD7 MYL3 MYL3 CPE CPE EDNRA EDNRA ISL1 ISL1 SMO SMO GATA4 GATA4 MESP1 MESP1 FGF8 FGF8 SMARCD3 SMARCD3 NRP2 NRP2 BMP2 BMP2 LOC103072649 LOC103072649 TBX5 TBX5 ZFPM1 ZFPM1 FOXF1 FOXF1 LOC103080655 LOC103080655 WHSC1 WHSC1 BMPR2 BMPR2 MYL10 MYL10 MYL2 MYL2 GATA3 GATA3 CITED2 CITED2 MEF2C MEF2C SFRP2 SFRP2 SEMA3C SEMA3C EGLN1 EGLN1 POU4F1 POU4F1 ADAMTS1 ADAMTS1 SMAD7 SMAD7 NKX2-5 NKX2-5 DSP DSP FOXH1 FOXH1 ADPRHL1 ADPRHL1 GRHL2 GRHL2 CAV3 CAV3 SMAD4 SMAD4 LOC103084351 LOC103084351 MED1 MED1 NOG NOG TBX2 TBX2 DHRS3 DHRS3 BMP10 BMP10 NPY5R NPY5R LOC103073422 LOC103073422 DLL4 DLL4 WNT11 WNT11 TGFBR1 TGFBR1 NOTCH1 NOTCH1 TGFB1 TGFB1 GSK3A GSK3A LOC103088826 LOC103088826 CYR61 CYR61 HES1 HES1 TNNI1 TNNI1 PPP1R13L PPP1R13L WNT5A WNT5A SRF SRF BMPR1A BMPR1A MYBPC3 MYBPC3 LOC103083860 LOC103083860 TEK TEK NOTCH2 NOTCH2 PTCD2 PTCD2 LOC103076632 LOC103076632 HAND2 HAND2 TNNT2 TNNT2 HEYL HEYL APLNR APLNR HAND1 HAND1 SOX4 SOX4 PKP2 PKP2 RYR2 RYR2 WNT2 WNT2 LRP2 LRP2 TNNC1 TNNC1 JAG1 JAG1 RBM15 RBM15 NPY2R NPY2R PROX1 PROX1 LOC103085851 LOC103085851 GATA6 GATA6 SMAD6 SMAD6 LOC103072909 LOC103072909 SLIT3 SLIT3 LOC103083261 LOC103083261 BMP7 BMP7 SAV1 SAV1 ADPRH ADPRH MKS1 MKS1 ZFPM2 ZFPM2 HEY2 HEY2 TBX20 TBX20 SOS1 SOS1 BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FHL2Four and a half LIM domains protein 2 isoform X1. (307 aa)
DNAH11LOW QUALITY PROTEIN: dynein, axonemal, heavy chain 11. (2874 aa)
ENGEndoglin. (661 aa)
GPR126LOW QUALITY PROTEIN: G protein-coupled receptor 126; Belongs to the G-protein coupled receptor 2 family. (967 aa)
PARVAAlpha-parvin. (412 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2305 aa)
MYL3Myosin light chain 3. (197 aa)
CPECarboxypeptidase E. (475 aa)
EDNRAEndothelin-1 receptor isoform X2. (318 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
GATA4Transcription factor GATA-4. (435 aa)
MESP1Mesoderm posterior protein 1. (267 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
LOC103072649Dynein heavy chain 11, axonemal-like. (1649 aa)
TBX5T-box transcription factor TBX5 isoform X1. (519 aa)
ZFPM1Zinc finger protein ZFPM1. (988 aa)
FOXF1Forkhead box protein F1. (377 aa)
LOC103080655chromodomain-helicase-DNA-binding protein 7-like. (414 aa)
WHSC1Histone-lysine N-methyltransferase NSD2 isoform X1. (1358 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
MYL10Myosin regulatory light chain 10. (147 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
EGLN1Egl nine homolog 1. (400 aa)
POU4F1POU domain protein. (388 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (940 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
NKX2-5Homeobox protein Nkx-2.5. (324 aa)
DSPDesmoplakin isoform X1. (2877 aa)
FOXH1Forkhead box protein H1. (360 aa)
ADPRHL1[Protein ADP-ribosylarginine] hydrolase-like protein 1. (354 aa)
GRHL2Grainyhead-like protein 2 homolog. (605 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
LOC103084351LOW QUALITY PROTEIN: T-box transcription factor TBX3-like. (737 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX2T-box transcription factor TBX2. (875 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
BMP10Bone morphogenetic protein 10. (421 aa)
NPY5RNeuropeptide Y receptor type 5. (456 aa)
LOC103073422LOW QUALITY PROTEIN: short stature homeobox protein 2-like. (359 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
CYR61Protein CYR61. (382 aa)
HES1Transcription factor HES-1. (280 aa)
TNNI1LOW QUALITY PROTEIN: troponin I, slow skeletal muscle. (224 aa)
PPP1R13LrelA-associated inhibitor isoform X1. (828 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SRFSerum response factor. (510 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1272 aa)
LOC103083860Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (227 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
NOTCH2Neurogenic locus notch homolog protein 2-like. (2471 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial isoform X1. (387 aa)
LOC103076632Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
TNNT2Troponin T, cardiac muscle. (280 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (323 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
SOX4Transcription factor SOX. (306 aa)
PKP2Plakophilin-2. (826 aa)
RYR2Ryanodine receptor 2-like. (4986 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4672 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
RBM15Putative RNA-binding protein 15 isoform X1. (1005 aa)
NPY2RNeuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
PROX1Prospero homeobox protein 1. (737 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
SMAD6Mothers against decapentaplegic homolog. (495 aa)
LOC103072909Protein HEG homolog 1-like. (136 aa)
SLIT3Slit homolog 3 protein. (1523 aa)
LOC103083261Protein HEG homolog 1-like. (1196 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
SAV1Protein salvador homolog 1. (384 aa)
ADPRH[Protein ADP-ribosylarginine] hydrolase. (362 aa)
MKS1LOW QUALITY PROTEIN: Meckel syndrome type 1 protein. (562 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (352 aa)
TBX20T-box transcription factor TBX20. (449 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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