STRINGSTRING
MAP3K8 MAP3K8 LRRK2 LRRK2 RIPK2 RIPK2 ARAF ARAF MAP3K15 MAP3K15 BRAF BRAF PBK PBK LOC103089656 LOC103089656 MAP3K11 MAP3K11 LOC103079692 LOC103079692 MAP3K10 MAP3K10 MAP3K6 MAP3K6 MAP3K4 MAP3K4 MAP3K14 MAP3K14 RIPK1 RIPK1 MAP3K7 MAP3K7 MAP3K13 MAP3K13 LOC103069061 LOC103069061 MAP3K9 MAP3K9 LOC103070824 LOC103070824
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (468 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2-like. (920 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X2. (609 aa)
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1193 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
LOC103089656Mitogen-activated protein kinase kinase kinase. (1017 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (858 aa)
LOC103079692Mitogen-activated protein kinase kinase kinase MLT-like isoform X1. (800 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (948 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1301 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1644 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (959 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (523 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (968 aa)
LOC103069061Mitogen-activated protein kinase kinase kinase 5-like. (127 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase 9 isoform X1. (1125 aa)
LOC103070824Leucine-rich repeat serine/threonine-protein kinase 2-like. (1609 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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