STRINGSTRING
LOC103090474 LOC103090474 IL17F IL17F LOC103068694 LOC103068694 LOC103069631 LOC103069631 IL17A IL17A LOC103079191 LOC103079191 BMP15 BMP15 WNT2 WNT2 LOC103081295 LOC103081295 LOC103090205 LOC103090205 CLCF1 CLCF1 MIF MIF FAM3B FAM3B WNT1 WNT1 LOC103068971 LOC103068971 TNFRSF11B TNFRSF11B KITLG KITLG IL25 IL25 IL31 IL31 IL33 IL33 TIMP1 TIMP1 LOC103083537 LOC103083537 SPP1 SPP1 CSF1 CSF1 WNT7A WNT7A IL6 IL6 CD40LG CD40LG GDF6 GDF6 LEFTY2 LEFTY2 WNT10B WNT10B LOC103090661 LOC103090661 LOC103068895 LOC103068895 NAMPT NAMPT CTF1 CTF1 IFNE IFNE LOC103069739 LOC103069739 CXCL11 CXCL11 CXCL13 CXCL13 GDF2 GDF2 IL12A IL12A GDF10 GDF10 LOC103084127 LOC103084127 LOC103089261 LOC103089261 BMP8B BMP8B WNT7B WNT7B LOC103090392 LOC103090392 LOC103068617 LOC103068617 WNT3A WNT3A LOC103077537 LOC103077537 LOC103073398 LOC103073398 NODAL NODAL LOC103091202 LOC103091202 LOC103069181 LOC103069181 LOC103073219 LOC103073219 CNTF CNTF CMTM3 CMTM3 LOC103080220 LOC103080220 LOC103069462 LOC103069462 LOC103073772 LOC103073772 IL7 IL7 CXCL10 CXCL10 CXCL9 CXCL9 C1QTNF4 C1QTNF4 CCL11 CCL11 WNT5A WNT5A IFNK IFNK CCL2 CCL2 WNT9A WNT9A NDP NDP LTB LTB LTA LTA LOC103080496 LOC103080496 CKLF CKLF TGFB3 TGFB3 CXCL16 CXCL16 TNFSF13 TNFSF13 NTN1 NTN1 WNT2B WNT2B XCL1 XCL1 LOC103075456 LOC103075456 WNT4 WNT4 WNT16 WNT16 CCL25 CCL25 CXCL17 CXCL17 TNF TNF CRLF1 CRLF1 GDF1 GDF1 IL13 IL13 GDF9 GDF9 SCG2 SCG2 WNT11 WNT11 GDF15 GDF15 LIF LIF OSM OSM GREM1 GREM1 IL9 IL9 IL34 IL34 TNFSF9 TNFSF9 LOC103070856 LOC103070856 LOC103071959 LOC103071959 IL4 IL4 IL3 IL3 WNT8A WNT8A IFNG IFNG CSF2 CSF2 IL5 IL5 CXCL14 CXCL14 CCL28 CCL28 GDF7 GDF7 IL15 IL15 FAM150A FAM150A BMP10 BMP10 PPBP PPBP PF4 PF4 FLT3LG FLT3LG IL18 IL18 IL22 IL22 IL2 IL2 CMTM8 CMTM8 LOC103080882 LOC103080882 LOC103071404 LOC103071404 CSF3 CSF3 LOC103071675 LOC103071675 IL26 IL26 TNFSF10 TNFSF10 VSTM1 VSTM1 BMP6 BMP6 IL12B IL12B LOC103073060 LOC103073060 MSTN MSTN WNT9B WNT9B WNT3 WNT3 INHBE INHBE GDF11 GDF11 LOC103071897 LOC103071897 INHBA INHBA CX3CL1 CX3CL1 LOC103080261 LOC103080261 CCL24 CCL24 THPO THPO INHBC INHBC LOC103087963 LOC103087963 FAM150B FAM150B EPO EPO IL11 IL11 GDF3 GDF3 CCL22 CCL22 IL23A IL23A IL8 IL8 CCL26 CCL26 LOC103091615 LOC103091615 IL17C IL17C LOC103076784 LOC103076784 TNFSF11 TNFSF11 WNT5B WNT5B IL24 IL24 FGF2 FGF2 BMP2 BMP2 WNT8B WNT8B IL16 IL16 INHBB INHBB GPI GPI IL10 IL10 CCL21 CCL21 TGFB2 TGFB2 IFNL3 IFNL3 IL20 IL20 CCL19 CCL19 IFNL1 IFNL1 CCL3 CCL3 BMP5 BMP5 IL32 IL32 CCL27 CCL27 GDF5 GDF5 CCL15 CCL15 LOC103089570 LOC103089570 CMTM5 CMTM5 IL17B IL17B BMP7 BMP7 TNFSF4 TNFSF4 CCL5 CCL5 FASLG FASLG IL37 IL37 IL1A IL1A LOC103084636 LOC103084636 BMP3 BMP3 IL1F10 IL1F10 EDN1 EDN1 LOC103069866 LOC103069866 IL1RN IL1RN CCL4 CCL4 WNT6 WNT6 CCL14 CCL14 IL36G IL36G IL1B IL1B WNT10A WNT10A IL36RN IL36RN BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103090474LOW QUALITY PROTEIN: cardiotrophin-2-like. (253 aa)
IL17Finterleukin-17F. (165 aa)
LOC103068694Interferon lambda-4-like. (142 aa)
LOC103069631c-C motif chemokine 1-like. (93 aa)
IL17Ainterleukin-17A-like. (153 aa)
LOC103079191Bone morphogenetic protein 8B-like. (180 aa)
BMP15Bone morphogenetic protein 15. (403 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC103081295C-C motif chemokine. (97 aa)
LOC103090205Uncharacterized protein LOC103090205. (298 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (215 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
FAM3BProtein FAM3B. (235 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LOC103068971Interferon lambda-3-like. (260 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
IL25Interleukin-25. (117 aa)
IL31LOW QUALITY PROTEIN: interleukin-31. (125 aa)
IL33LOW QUALITY PROTEIN: interleukin-33. (485 aa)
TIMP1Metalloproteinase inhibitor 1. (257 aa)
LOC103083537Interleukin-13-like. (81 aa)
SPP1Osteopontin isoform X1. (296 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
IL6LOW QUALITY PROTEIN: interleukin-6. (243 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
GDF6Growth/differentiation factor 6. (461 aa)
LEFTY2Left-right determination factor. (367 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC103090661Interferon alpha-1-like. (189 aa)
LOC103068895Interferon omega-1-like. (227 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
CTF1Cardiotrophin-1. (185 aa)
IFNEInterferon epsilon. (193 aa)
LOC103069739Interferon alpha-1-like. (189 aa)
CXCL11c-X-C motif chemokine 11. (100 aa)
CXCL13c-X-C motif chemokine 13. (109 aa)
GDF2Growth/differentiation factor 2. (431 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (257 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (440 aa)
LOC103084127Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
LOC103089261Bone morphogenetic protein 8B-like. (403 aa)
BMP8BBone morphogenetic protein 8B. (403 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC103090392Interferon omega-1-like. (195 aa)
LOC103068617Interferon alpha-1-like. (188 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC103077537Bone morphogenetic protein 8B-like. (136 aa)
LOC103073398Left-right determination factor. (367 aa)
NODALNodal homolog. (349 aa)
LOC103091202Interferon alpha-1-like. (188 aa)
LOC103069181Interferon alpha-1-like. (189 aa)
LOC103073219LOW QUALITY PROTEIN: interferon alpha-8-like. (248 aa)
CNTFCiliary neurotrophic factor. (200 aa)
CMTM3CKLF-like MARVEL transmembrane domain-containing protein 3. (182 aa)
LOC103080220CKLF-like MARVEL transmembrane domain-containing protein 2-like. (228 aa)
LOC103069462Interferon omega-1-like. (195 aa)
LOC103073772Interferon beta-2-like. (186 aa)
IL7Interleukin-7 isoform X2. (178 aa)
CXCL10C-X-C motif chemokine. (103 aa)
CXCL9C-X-C motif chemokine. (126 aa)
C1QTNF4Complement C1q tumor necrosis factor-related protein 4. (324 aa)
CCL11C-C motif chemokine. (99 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
IFNKInterferon kappa. (207 aa)
CCL2C-C motif chemokine. (99 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
NDPNorrin. (133 aa)
LTBLymphotoxin-beta; Belongs to the tumor necrosis factor family. (247 aa)
LTALymphotoxin-alpha; Belongs to the tumor necrosis factor family. (205 aa)
LOC103080496Uncharacterized protein LOC103080496. (390 aa)
CKLFChemokine-like factor. (96 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
CXCL16c-X-C motif chemokine 16. (251 aa)
TNFSF13Tumor necrosis factor ligand superfamily member 13 isoform X1; Belongs to the tumor necrosis factor family. (247 aa)
NTN1Netrin-1 isoform X1. (604 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
XCL1Lymphotactin. (112 aa)
LOC103075456c-C motif chemokine 8-like. (99 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
CCL25c-C motif chemokine 25. (151 aa)
CXCL17VEGF coregulated chemokine 1. (119 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CRLF1Cytokine receptor-like factor 1. (616 aa)
GDF1Embryonic growth/differentiation factor 1. (370 aa)
IL13Interleukin-13. (132 aa)
GDF9Growth/differentiation factor 9. (454 aa)
SCG2Secretogranin-2. (616 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
GDF15Growth/differentiation factor 15. (308 aa)
LIFLeukemia inhibitory factor. (202 aa)
OSMoncostatin-M. (246 aa)
GREM1Gremlin. (184 aa)
IL9Interleukin-9. (141 aa)
IL34LOW QUALITY PROTEIN: interleukin-34. (268 aa)
TNFSF9Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (284 aa)
LOC103070856C-X-C motif chemokine. (113 aa)
LOC103071959C-X-C motif chemokine. (100 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa)
IL3Interleukin-3. (144 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CXCL14c-X-C motif chemokine 14. (99 aa)
CCL28C-C motif chemokine. (127 aa)
GDF7Growth/differentiation factor 7. (457 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
FAM150AProtein FAM150A. (131 aa)
BMP10Bone morphogenetic protein 10. (421 aa)
PPBPC-X-C motif chemokine. (119 aa)
PF4C-X-C motif chemokine. (112 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (296 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
IL22Interleukin-22. (189 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
CMTM8CKLF-like MARVEL transmembrane domain-containing protein 8. (173 aa)
LOC103080882Uncharacterized protein LOC103080882. (574 aa)
LOC103071404C-X-C motif chemokine. (227 aa)
CSF3Granulocyte colony-stimulating factor. (195 aa)
LOC103071675C-X-C motif chemokine. (196 aa)
IL26Interleukin-26. (170 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
VSTM1V-set and transmembrane domain-containing protein 1. (245 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC103073060Synaptopodin 2-like protein-like. (392 aa)
MSTNGrowth/differentiation factor 8. (366 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
INHBEInhibin beta E chain. (351 aa)
GDF11Growth/differentiation factor 11. (404 aa)
LOC103071897Stromal cell-derived factor 1-like isoform X2; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
CX3CL1Fractalkine. (388 aa)
LOC103080261C-C motif chemokine. (201 aa)
CCL24c-C motif chemokine 24. (130 aa)
THPOThrombopoietin isoform X1. (319 aa)
INHBCInhibin beta C chain. (352 aa)
LOC103087963Uncharacterized protein LOC103087963. (275 aa)
FAM150BProtein FAM150B. (152 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
IL11Interleukin-11 isoform X1. (199 aa)
GDF3Growth/differentiation factor 3. (364 aa)
CCL22C-C motif chemokine. (93 aa)
IL23AInterleukin-23 subunit alpha. (187 aa)
IL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CCL26c-C motif chemokine 26. (94 aa)
LOC103091615Secreted and transmembrane protein 1-like. (189 aa)
IL17Cinterleukin-17C. (344 aa)
LOC103076784Glucose-6-phosphate isomerase; Belongs to the GPI family. (821 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
IL24Interleukin-24. (177 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1325 aa)
INHBBInhibin beta B chain. (511 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
IL10Interleukin-10. (178 aa)
CCL21c-C motif chemokine 21. (131 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
IFNL3LOW QUALITY PROTEIN: interferon, lambda 3. (313 aa)
IL20LOW QUALITY PROTEIN: interleukin-20. (180 aa)
CCL19C-C motif chemokine. (100 aa)
IFNL1LOW QUALITY PROTEIN: interferon, lambda 1. (192 aa)
CCL3LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3. (88 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
IL32LOW QUALITY PROTEIN: interleukin 32. (184 aa)
CCL27LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 27. (95 aa)
GDF5Growth/differentiation factor 5. (499 aa)
CCL15C-C motif chemokine. (126 aa)
LOC103089570C-C motif chemokine. (90 aa)
CMTM5CKLF-like MARVEL transmembrane domain-containing protein 5. (184 aa)
IL17Binterleukin-17B. (180 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
TNFSF4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa)
CCL5C-C motif chemokine. (91 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
IL37Interleukin-37. (198 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
LOC103084636Uncharacterized protein. (81 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
IL1F10Interleukin-1. (144 aa)
EDN1Endothelin-1. (202 aa)
LOC103069866Interleukin-1. (124 aa)
IL1RNInterleukin-1. (177 aa)
CCL4C-C motif chemokine. (92 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
CCL14LOW QUALITY PROTEIN: c-C motif chemokine 14. (101 aa)
IL36GInterleukin-1. (172 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
IL36RNLOW QUALITY PROTEIN: interleukin-36 receptor antagonist protein. (179 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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