STRINGSTRING
PTPRK PTPRK LTBP4 LTBP4 TGFB1 TGFB1 TGFB3 TGFB3 USP9X USP9X ARRB2 ARRB2 LOC103085419 LOC103085419 LPXN LPXN ITGB8 ITGB8 NODAL NODAL CDH5 CDH5 TGFBR2 TGFBR2 TWSG1 TWSG1 HPGD HPGD SIRT1 SIRT1 SMAD1 SMAD1 HIPK2 HIPK2 LOC103088671 LOC103088671 SMAD2 SMAD2 LOC103089209 LOC103089209 CITED2 CITED2 CITED1 CITED1 MSTN MSTN WFIKKN2 WFIKKN2 COL3A1 COL3A1 ZYX ZYX SMAD7 SMAD7 FOXH1 FOXH1 LOC103088938 LOC103088938 ZMIZ1 ZMIZ1 NRROS NRROS SKIL SKIL SMAD4 SMAD4 SMAD9 SMAD9 LTBP3 LTBP3 GLG1 GLG1 LRRC32 LRRC32 TGFBR3L TGFBR3L JUN JUN CLDN5 CLDN5 ONECUT1 ONECUT1 ZFYVE9 ZFYVE9 TGFBR1 TGFBR1 SMAD5 SMAD5 ENG ENG TGFB2 TGFB2 LOC103077614 LOC103077614 TGFBR3 TGFBR3 ADAM9 ADAM9 APPL2 APPL2 SRC SRC FERMT2 FERMT2 CHST11 CHST11 ACVR1 ACVR1 SMAD3 SMAD3 PXN PXN PML PML STAT3 STAT3 ITGB5 ITGB5 FUT8 FUT8 FLCN FLCN SMAD6 SMAD6 CAV2 CAV2 MTMR4 MTMR4 LOC103069249 LOC103069249 USP15 USP15 ACVRL1 ACVRL1 APPL1 APPL1 LOC103068420 LOC103068420 TAB1 TAB1 NLK NLK ONECUT2 ONECUT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1461 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1628 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
USP9XProbable ubiquitin carboxyl-terminal hydrolase FAF-X-like; Belongs to the peptidase C19 family. (2548 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
LOC103085419Ubiquitin carboxyl-terminal hydrolase 15-like. (235 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
NODALNodal homolog. (349 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
TWSG1Twisted gastrulation protein homolog 1. (222 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
SIRT1LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1180 aa)
LOC103088671N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C-like. (333 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LOC103089209N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B-like. (321 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (221 aa)
MSTNGrowth/differentiation factor 8. (366 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (574 aa)
COL3A1Collagen alpha-1(III) chain-like. (1462 aa)
ZYXZyxin isoform X1. (594 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
FOXH1Forkhead box protein H1. (360 aa)
LOC103088938N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A-like. (313 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1065 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
SKILSki-like protein isoform X1. (683 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
SMAD9Mothers against decapentaplegic homolog. (430 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1301 aa)
GLG1Golgi apparatus protein 1-like. (1164 aa)
LRRC32Leucine-rich repeat-containing protein 32. (703 aa)
TGFBR3LTransforming growth factor-beta receptor type 3-like protein. (389 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ONECUT1One cut domain family member. (464 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1420 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ENGEndoglin. (661 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC103077614Uncharacterized protein LOC103077614. (220 aa)
TGFBR3Transforming growth factor beta receptor type 3. (851 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9. (819 aa)
APPL2DCC-interacting protein 13-beta isoform X2. (668 aa)
SRCTyrosine-protein kinase. (548 aa)
FERMT2Fermitin family homolog 2 isoform X1. (687 aa)
CHST11Carbohydrate sulfotransferase. (343 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PXNPaxillin-like isoform X1; Belongs to the paxillin family. (591 aa)
PMLProtein PML. (848 aa)
STAT3Signal transducer and activator of transcription. (654 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
FLCNFolliculin. (579 aa)
SMAD6Mothers against decapentaplegic homolog. (495 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1210 aa)
LOC103069249Collagen alpha-2(I) chain-like isoform X3. (1370 aa)
USP15Ubiquitin carboxyl-terminal hydrolase 15; Belongs to the peptidase C19 family. (648 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
APPL1DCC-interacting protein 13-alpha. (708 aa)
LOC103068420EP300-interacting inhibitor of differentiation 2-like. (203 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
ONECUT2One cut domain family member 2. (320 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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