STRINGSTRING
GNA12 GNA12 RASGEF1C RASGEF1C BRAP BRAP MRAS MRAS RAP2A RAP2A NGFR NGFR ITGA3 ITGA3 RAPGEF3 RAPGEF3 EPS8L2 EPS8L2 DBNL DBNL RHOG RHOG ARHGDIB ARHGDIB TRIM28 TRIM28 FAM65A FAM65A NCKAP1 NCKAP1 USP8 USP8 LOC103087073 LOC103087073 RIT1 RIT1 LOC103083128 LOC103083128 RANGRF RANGRF ARHGEF11 ARHGEF11 RAPGEFL1 RAPGEFL1 PDPN PDPN KPNB1 KPNB1 CYFIP1 CYFIP1 RAP2C RAP2C RALA RALA CCNA2 CCNA2 RAC3 RAC3 RRAS RRAS NRAS NRAS RAP1B RAP1B RASGRP2 RASGRP2 DOK3 DOK3 PHACTR4 PHACTR4 DNMT1 DNMT1 JUN JUN RRAS2 RRAS2 ARHGDIA ARHGDIA MYO9B MYO9B RHOJ RHOJ SYNGAP1 SYNGAP1 CDC42EP2 CDC42EP2 DOK1 DOK1 CDC42 CDC42 WASF2 WASF2 RFXANK RFXANK RAB4B RAB4B RAPGEF4 RAPGEF4 RGL2 RGL2 RASGRF1 RASGRF1 CNKSR1 CNKSR1 RASGRP1 RASGRP1 LOC103074616 LOC103074616 RHOV RHOV IQGAP3 IQGAP3 PPP1R21 PPP1R21 ZNF304 ZNF304 LOC103080689 LOC103080689 AIF1 AIF1 RAB9A RAB9A ROCK2 ROCK2 GDI1 GDI1 RAB12 RAB12 ARHGAP35 ARHGAP35 RASGRF2 RASGRF2 ARHGDIG ARHGDIG RASGEF1A RASGEF1A NISCH NISCH RASSF1 RASSF1 PLEKHG5 PLEKHG5 RAPGEF1 RAPGEF1 RAB33A RAB33A ARHGEF12 ARHGEF12 CDH13 CDH13 RASGRP3 RASGRP3 WASF1 WASF1 RGL1 RGL1 NF1 NF1 LOC103080281 LOC103080281 LOC103076697 LOC103076697 ARHGAP5 ARHGAP5 RAB15 RAB15 LOC103069249 LOC103069249 RAB21 RAB21 GPSM2 GPSM2 RAP1A RAP1A LOC103082455 LOC103082455 RALGPS2 RALGPS2 ERAS ERAS WAS WAS BCL6 BCL6 RAB35 RAB35 MAPKAPK5 MAPKAPK5 DOK2 DOK2 CSF1 CSF1 PTPLAD1 PTPLAD1 RAB9B RAB9B CTNNAL1 CTNNAL1 NKIRAS2 NKIRAS2 TMEM19 TMEM19 RASGEF1B RASGEF1B EPS8L3 EPS8L3 RAPGEF2 RAPGEF2 RAB4A RAB4A LOC103075606 LOC103075606 LOC103090788 LOC103090788 RAB30 RAB30 SOS1 SOS1 ELMO1 ELMO1 CDC42EP3 CDC42EP3 RAPGEF5 RAPGEF5 RALGDS RALGDS RACGAP1 RACGAP1 LAT LAT LOC103082673 LOC103082673 TAX1BP3 TAX1BP3 KSR1 KSR1 RHOH RHOH RABGEF1 RABGEF1 KRAS KRAS SOS2 SOS2 RHOA RHOA AGTR1 AGTR1 CDC42EP1 CDC42EP1 KSR2 KSR2 CDC42EP4 CDC42EP4 PDIA2 PDIA2 RERG RERG RAC2 RAC2 CELSR1 CELSR1 SGSM3 SGSM3 GNA13 GNA13 RAB33B RAB33B RASGRP4 RASGRP4 LOC103083466 LOC103083466 KIAA1598 KIAA1598 RALGPS1 RALGPS1 PLCE1 PLCE1 SYNJ2BP SYNJ2BP LOC103088976 LOC103088976 PRKD1 PRKD1 FARP2 FARP2 KIAA0355 KIAA0355 GPR56 GPR56 LOC103075688 LOC103075688 LOC103086614 LOC103086614 NKIRAS1 NKIRAS1 RALB RALB CDK2 CDK2 CDKN1A CDKN1A DGKI DGKI CDC42EP5 CDC42EP5 RB1 RB1 RAB39B RAB39B PLEKHG7 PLEKHG7 EPS8 EPS8 HRAS HRAS EPS8L1 EPS8L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNA12Guanine nucleotide-binding protein subunit alpha-12. (480 aa)
RASGEF1Cras-GEF domain-containing family member 1C. (466 aa)
BRAPBRCA1-associated protein. (592 aa)
MRASRas-related protein M-Ras isoform X1. (208 aa)
RAP2ARas-related protein Rap-2a. (105 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2. (631 aa)
DBNLDrebrin-like protein isoform X1. (438 aa)
RHOGRho-related GTP-binding protein RhoG. (191 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (199 aa)
TRIM28Transcription intermediary factor 1-beta. (830 aa)
FAM65AProtein FAM65A isoform X3. (1249 aa)
NCKAP1Nck-associated protein 1. (1126 aa)
USP8LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
LOC103087073Ras-related protein Rab-39A-like. (217 aa)
RIT1GTP-binding protein Rit1. (218 aa)
LOC103083128Ras-related protein Rap-2a-like. (200 aa)
RANGRFRan guanine nucleotide release factor isoform X2. (186 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform X1. (1559 aa)
RAPGEFL1Rap guanine nucleotide exchange factor-like 1. (486 aa)
PDPNPodoplanin. (161 aa)
KPNB1Importin subunit beta-1 isoform X1. (805 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
RAP2CRas-related protein Rap-2c isoform X1. (183 aa)
RALARas-related protein Ral-A. (206 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
RRASRas-related protein R-Ras. (218 aa)
NRASGTPase NRas. (189 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X1. (608 aa)
DOK3Docking protein 3. (449 aa)
PHACTR4Phosphatase and actin regulator. (816 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1615 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
RRAS2Ras-related protein R-Ras2 isoform X1. (127 aa)
ARHGDIARho GDP-dissociation inhibitor 1 isoform X1. (204 aa)
MYO9BUnconventional myosin-IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2153 aa)
RHOJRho-related GTP-binding protein RhoJ. (236 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1324 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
DOK1Docking protein 1 isoform X1. (483 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
RFXANKDNA-binding protein RFXANK. (260 aa)
RAB4BRas-related protein Rab-4B isoform X2. (232 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4 isoform X1. (1011 aa)
RGL2Ral guanine nucleotide dissociation stimulator-like 2. (780 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1 isoform X2. (1273 aa)
CNKSR1Connector enhancer of kinase suppressor of ras 1. (710 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (797 aa)
LOC103074616Uncharacterized protein C15orf62 homolog, mitochondrial. (175 aa)
RHOVRho-related GTP-binding protein RhoV. (236 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1612 aa)
PPP1R21Protein phosphatase 1 regulatory subunit 21 isoform X1. (780 aa)
ZNF304Zinc finger protein 304-like. (661 aa)
LOC103080689Zinc finger protein 304-like. (661 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
RAB12Ras-related protein Rab-12. (244 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
ARHGDIGRho GDP-dissociation inhibitor 3. (225 aa)
RASGEF1Aras-GEF domain-containing family member 1A. (488 aa)
NISCHNischarin isoform X1. (1494 aa)
RASSF1Ras association domain-containing protein 1 isoform X3. (344 aa)
PLEKHG5Pleckstrin homology domain-containing family G member 5 isoform X1. (1074 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1133 aa)
RAB33ARas-related protein Rab-33A. (237 aa)
ARHGEF12LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 12. (1563 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
RASGRP3Ras guanyl-releasing protein 3 isoform X1. (740 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
RGL1Ral guanine nucleotide dissociation stimulator-like 1 isoform X1. (800 aa)
NF1Neurofibromin isoform X1. (2841 aa)
LOC103080281Probable protein BRICK1-like. (75 aa)
LOC103076697Rac GTPase-activating protein 1-like. (304 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
RAB15Ras-related protein Rab-15. (212 aa)
LOC103069249Collagen alpha-2(I) chain-like isoform X3. (1370 aa)
RAB21Ras-related protein Rab-21. (222 aa)
GPSM2LOW QUALITY PROTEIN: G-protein-signaling modulator 2. (684 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
RALGPS2Ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1. (583 aa)
ERASGTPase ERas. (233 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
BCL6B-cell lymphoma 6 protein isoform X1. (728 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (473 aa)
DOK2Docking protein 2. (411 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
PTPLAD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
RAB9BRas-related protein Rab-9B. (201 aa)
CTNNAL1Alpha-catulin. (615 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (191 aa)
TMEM19Transmembrane protein 19. (358 aa)
RASGEF1Bras-GEF domain-containing family member 1B isoform X1. (472 aa)
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (565 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1483 aa)
RAB4ARas-related protein Rab-4A. (218 aa)
LOC103075606Ras-related protein Rap-2a-like. (183 aa)
LOC103090788Rho-related GTP-binding protein RhoU-like. (255 aa)
RAB30Ras-related protein Rab-30 isoform X1. (203 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
CDC42EP3Cdc42 effector protein 3. (254 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
RALGDSRal guanine nucleotide dissociation stimulator. (842 aa)
RACGAP1Rac GTPase-activating protein 1. (344 aa)
LATLinker for activation of T-cells family member 1. (260 aa)
LOC103082673Putative ubiquitin carboxyl-terminal hydrolase 50-like; Belongs to the peptidase C19 family. (373 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
KSR1Kinase suppressor of Ras 1. (757 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
RABGEF1Rab5 GDP/GTP exchange factor isoform X1. (492 aa)
KRASGTPase KRas. (188 aa)
SOS2Son of sevenless homolog 2-like. (1272 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
CDC42EP1Cdc42 effector protein 1. (361 aa)
KSR2Kinase suppressor of Ras 2. (949 aa)
CDC42EP4Cdc42 effector protein 4. (353 aa)
PDIA2Protein disulfide-isomerase A2. (529 aa)
RERGRas-related and estrogen-regulated growth inhibitor isoform X1. (199 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3319 aa)
SGSM3Small G protein signaling modulator 3. (782 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
RAB33BRas-related protein Rab-33B. (229 aa)
RASGRP4RAS guanyl-releasing protein 4. (677 aa)
LOC103083466Rho-related GTP-binding protein RhoG-like. (191 aa)
KIAA1598Shootin-1 isoform X1. (571 aa)
RALGPS1Ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X3. (608 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
SYNJ2BPSynaptojanin-2-binding protein. (145 aa)
LOC103088976Ras-related protein Rap-1b-like isoform X1. (165 aa)
PRKD1Serine/threonine-protein kinase D1-like. (801 aa)
FARP2FERM, RhoGEF and pleckstrin domain-containing protein 2. (1466 aa)
KIAA0355Uncharacterized protein KIAA0355 homolog. (1070 aa)
GPR56G-protein coupled receptor 56 isoform X1; Belongs to the G-protein coupled receptor 2 family. (692 aa)
LOC103075688LOW QUALITY PROTEIN: uncharacterized protein C12orf74 homolog. (353 aa)
LOC103086614LOW QUALITY PROTEIN: death domain-containing membrane protein NRADD-like. (232 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (201 aa)
RALBRas-related protein Ral-B. (206 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (164 aa)
DGKIDiacylglycerol kinase. (1078 aa)
CDC42EP5Cdc42 effector protein 5. (153 aa)
RB1Retinoblastoma-associated protein isoform X1. (929 aa)
RAB39BRas-related protein Rab-39B. (286 aa)
PLEKHG7LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 7. (558 aa)
EPS8Epidermal growth factor receptor kinase substrate 8. (812 aa)
HRASGTPase HRas isoform X1. (189 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (722 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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