STRINGSTRING
MMP14 MMP14 ITGAV ITGAV COL11A1 COL11A1 DUSP2 DUSP2 SSBP3 SSBP3 CTR9 CTR9 DUSP5 DUSP5 FGF8 FGF8 SETD2 SETD2 LEO1 LEO1 MED12 MED12 MMP15 MMP15 LDB1 LDB1 EPB41L5 EPB41L5 HDAC1 HDAC1 ITGA5 ITGA5 ITGA7 ITGA7 INHBA INHBA SOX7 SOX7 DUSP1 DUSP1 CTNNB1 CTNNB1 ARC ARC SMAD4 SMAD4 NOG NOG LHX1 LHX1 PAX9 PAX9 LOC103077930 LOC103077930 SOX17 SOX17 ITGA4 ITGA4 WNT8A WNT8A RTF1 RTF1 ONECUT1 ONECUT1 NOTCH1 NOTCH1 TGFB1 TGFB1 MMP2 MMP2 LOC103088826 LOC103088826 EOMES EOMES FN1 FN1 PELO PELO NR0B1 NR0B1 BMPR1A BMPR1A BPTF BPTF COL12A1 COL12A1 LAMB1 LAMB1 NODAL NODAL ZFP36L1 ZFP36L1 COL4A2 COL4A2 GRB2 GRB2 COL8A1 COL8A1 LOC103090748 LOC103090748 VTN VTN MIXL1 MIXL1 EXT1 EXT1 LAMB3 LAMB3 COL6A1 COL6A1 MMP9 MMP9 PAF1 PAF1 LOC103085851 LOC103085851 GATA6 GATA6 MMP8 MMP8 MAP2K1 MAP2K1 LOC103085466 LOC103085466 ITGB5 ITGB5 LAMA3 LAMA3 SMAD3 SMAD3 COL7A1 COL7A1 HMGA2 HMGA2 BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP14Matrix metalloproteinase-14 isoform X2. (582 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
COL11A1Collagen alpha-1(XI) chain-like isoform X1. (1824 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (311 aa)
SSBP3Single-stranded DNA-binding protein 3 isoform X1. (388 aa)
CTR9RNA polymerase-associated protein CTR9 homolog. (1176 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2562 aa)
LEO1RNA polymerase-associated protein LEO1 isoform X1. (666 aa)
MED12Mediator of RNA polymerase II transcription subunit 12 isoform X1. (2185 aa)
MMP15Matrix metalloproteinase-15. (677 aa)
LDB1LIM domain-binding protein 1 isoform X1. (411 aa)
EPB41L5LOW QUALITY PROTEIN: band 4.1-like protein 5. (505 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (538 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
SOX7Transcription factor SOX-7. (392 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
ARCActivity-regulated cytoskeleton-associated protein. (396 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
PAX9Paired box protein Pax-9 isoform X1. (342 aa)
LOC103077930Thyroid transcription factor 1-like isoform X2. (402 aa)
SOX17Transcription factor SOX-17. (405 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
RTF1RNA polymerase-associated protein RTF1 homolog. (710 aa)
ONECUT1One cut domain family member. (464 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
MMP272 kDa type IV collagenase. (584 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
EOMESEomesodermin homolog isoform X1. (694 aa)
FN1LOW QUALITY PROTEIN: fibronectin. (2483 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BPTFNucleosome-remodeling factor subunit BPTF isoform X1. (2773 aa)
COL12A1Collagen alpha-1(XII) chain. (3120 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
NODALNodal homolog. (349 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1-like. (338 aa)
COL4A2Collagen alpha-2(IV) chain. (1671 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
COL8A1Collagen alpha-1(VIII) chain isoform X1. (745 aa)
LOC103090748Zinc finger protein 36, C3H1 type-like 1-like. (226 aa)
VTNVitronectin isoform X1. (565 aa)
MIXL1Homeobox protein MIXL1. (237 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (750 aa)
LAMB3Laminin subunit beta-3. (1172 aa)
COL6A1Collagen alpha-1(VI) chain. (1150 aa)
MMP9Matrix metalloproteinase-9. (708 aa)
PAF1RNA polymerase II-associated factor 1 homolog isoform X1. (526 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
MMP8Neutrophil collagenase. (468 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
LOC103085466Band 4.1-like protein 5-like. (256 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LAMA3Laminin subunit alpha-3. (3338 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
COL7A1Collagen alpha-1(VII) chain. (2986 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.