STRINGSTRING
CORO2B CORO2B RHOA RHOA LOC103068383 LOC103068383 LOC103070587 LOC103070587 FERMT2 FERMT2 FZD4 FZD4 CORO1C CORO1C EDIL3 EDIL3 MYOC MYOC LOC103085466 LOC103085466 AJAP1 AJAP1 RASA1 RASA1 CSF1 CSF1 LOC103085751 LOC103085751 KIAA2022 KIAA2022 GSK3B GSK3B RAC1 RAC1 BCL6 BCL6 FBLN2 FBLN2 LOC103082455 LOC103082455 CRKL CRKL DDR1 DDR1 JAG1 JAG1 NF1 NF1 DMTN DMTN HRG HRG KDR KDR WNT1 WNT1 ACVRL1 ACVRL1 UTRN UTRN PPM1F PPM1F CDH13 CDH13 C1QBP C1QBP ABL1 ABL1 FBLN1 FBLN1 TRIOBP TRIOBP CRK CRK VTN VTN EFNA5 EFNA5 AP1AR AP1AR NID1 NID1 LIMCH1 LIMCH1 TSC1 TSC1 ONECUT2 ONECUT2 COL8A1 COL8A1 LOC103070453 LOC103070453 HSD17B12 HSD17B12 PTPRJ PTPRJ RIN2 RIN2 TESK1 TESK1 MACF1 MACF1 RAC2 RAC2 PDGFB PDGFB THY1 THY1 UNC13D UNC13D ITGB1BP1 ITGB1BP1 SPOCK2 SPOCK2 LIMS1 LIMS1 PIK3R1 PIK3R1 CASK CASK LRRC16A LRRC16A TEK TEK ARHGAP6 ARHGAP6 SEMA3E SEMA3E ALOX15 ALOX15 SFRP1 SFRP1 ITGB3 ITGB3 GPM6B GPM6B FN1 FN1 LOC103072951 LOC103072951 MYF5 MYF5 TBCD TBCD CYR61 CYR61 FLNA FLNA LOC103073034 LOC103073034 ADAM15 ADAM15 CCDC80 CCDC80 VEGFA VEGFA CCL25 CCL25 DOCK5 DOCK5 ILK ILK PRKCE PRKCE CDC42 CDC42 NOTCH1 NOTCH1 RCC2 RCC2 THBS1 THBS1 APOA1 APOA1 CDK6 CDK6 ONECUT1 ONECUT1 ARL2 ARL2 RSU1 RSU1 P4HB P4HB LRRC45 LRRC45 ACTG1 ACTG1 S100A10 S100A10 GREM1 GREM1 LIMS2 LIMS2 SPOCK1 SPOCK1 CAMSAP3 CAMSAP3 LOC103081423 LOC103081423 FUT1 FUT1 EMID1 EMID1 CORO2A CORO2A CCL28 CCL28 EFEMP2 EFEMP2 CASS4 CASS4 RRAS RRAS TACSTD2 TACSTD2 FMN1 FMN1 BCL2 BCL2 PDPN PDPN SKAP1 SKAP1 AGR2 AGR2 NEDD9 NEDD9 PTPRA PTPRA MFI2 MFI2 APOD APOD LOC103071971 LOC103071971 WDPCP WDPCP PTK2B PTK2B RREB1 RREB1 LOC103088938 LOC103088938 PIK3CB PIK3CB PLET1 PLET1 STK4 STK4 EPHA1 EPHA1 HOXA7 HOXA7 JUP JUP LOC103089209 LOC103089209 RELL2 RELL2 KANK1 KANK1 DLC1 DLC1 LOC103088671 LOC103088671 EPHA3 EPHA3 COL16A1 COL16A1 BRAF BRAF SPRY4 SPRY4 PLAU PLAU CALR CALR EPB41L5 EPB41L5 FZD7 FZD7 ECM2 ECM2 VWC2 VWC2 VCL VCL FOXF1 FOXF1 EGFLAM EGFLAM PLEKHA2 PLEKHA2 LOC103090986 LOC103090986 COL26A1 COL26A1 ACER2 ACER2 LDB1 LDB1 LOC103083182 LOC103083182 VIT VIT ANGPT2 ANGPT2 ACTN4 ACTN4 LOC103091262 LOC103091262 FERMT1 FERMT1 PEAK1 PEAK1 EMILIN1 EMILIN1 NRP1 NRP1 SLK SLK EGFL6 EGFL6 CCL21 CCL21 CIB1 CIB1 BST1 BST1 MYADM MYADM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
LOC103068383Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-like. (1659 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
FERMT2Fermitin family homolog 2 isoform X1. (687 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
EDIL3EGF-like repeat and discoidin I-like domain-containing protein 3-like isoform X1. (480 aa)
MYOCLOW QUALITY PROTEIN: myocilin. (480 aa)
LOC103085466Band 4.1-like protein 5-like. (256 aa)
AJAP1Adherens junction-associated protein 1. (488 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
LOC103085751Junction plakoglobin-like. (330 aa)
KIAA2022Uncharacterized protein KIAA2022 homolog. (1515 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
BCL6B-cell lymphoma 6 protein isoform X1. (728 aa)
FBLN2Fibulin-2. (1217 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
CRKLCrk-like protein. (303 aa)
DDR1Tyrosine-protein kinase receptor. (923 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NF1Neurofibromin isoform X1. (2841 aa)
DMTNDematin isoform X1. (405 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (472 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
UTRNLOW QUALITY PROTEIN: utrophin. (3432 aa)
PPM1FProtein phosphatase 1F-like. (418 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (706 aa)
TRIOBPTRIO and F-actin-binding protein-like isoform X1. (660 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
VTNVitronectin isoform X1. (565 aa)
EFNA5ephrin-A5; Belongs to the ephrin family. (228 aa)
AP1ARAP-1 complex-associated regulatory protein. (302 aa)
NID1LOW QUALITY PROTEIN: nidogen-1. (1242 aa)
LIMCH1LOW QUALITY PROTEIN: LIM and calponin homology domains-containing protein 1. (1060 aa)
TSC1Hamartin isoform X1. (1170 aa)
ONECUT2One cut domain family member 2. (320 aa)
COL8A1Collagen alpha-1(VIII) chain isoform X1. (745 aa)
LOC103070453TRIO and F-actin-binding protein-like. (896 aa)
HSD17B12Estradiol 17-beta-dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1155 aa)
RIN2LOW QUALITY PROTEIN: ras and Rab interactor 2. (940 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
MACF1Microtubule-actin cross-linking factor 1. (5423 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
UNC13DProtein unc-13 homolog D. (1090 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
SPOCK2Testican-2. (423 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (386 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CASKPeripheral plasma membrane protein CASK isoform X2; Belongs to the MAGUK family. (926 aa)
LRRC16ALeucine-rich repeat-containing protein 16A-like isoform X1. (1372 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
ARHGAP6Rho GTPase-activating protein 6. (977 aa)
SEMA3Esemaphorin-3E-like; Belongs to the semaphorin family. (715 aa)
ALOX15LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
GPM6BNeuronal membrane glycoprotein M6-b isoform X6. (324 aa)
FN1LOW QUALITY PROTEIN: fibronectin. (2483 aa)
LOC103072951Extracellular matrix protein 2-like. (404 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (234 aa)
TBCDTubulin-specific chaperone D. (1258 aa)
CYR61Protein CYR61. (382 aa)
FLNAfilamin-A isoform X1. (2647 aa)
LOC103073034Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
CCDC80Coiled-coil domain-containing protein 80 isoform X1. (953 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
CCL25c-C motif chemokine 25. (151 aa)
DOCK5Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (1772 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. (493 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
RCC2Protein RCC2 isoform X1. (520 aa)
THBS1Thrombospondin-1. (1170 aa)
APOA1Apolipoprotein A-I. (265 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ONECUT1One cut domain family member. (464 aa)
ARL2ADP-ribosylation factor-like protein 2 isoform X1; Belongs to the small GTPase superfamily. Arf family. (184 aa)
RSU1Ras suppressor protein 1 isoform X1. (277 aa)
P4HBProtein disulfide-isomerase. (510 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
GREM1Gremlin. (184 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
SPOCK1Testican-1 isoform X1. (442 aa)
CAMSAP3LOW QUALITY PROTEIN: calmodulin-regulated spectrin-associated protein 3. (1239 aa)
LOC103081423Target of Nesh-SH3-like. (154 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (365 aa)
EMID1EMI domain-containing protein 1 isoform X1. (439 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)
CCL28C-C motif chemokine. (127 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (442 aa)
CASS4Cas scaffolding protein family member 4. (801 aa)
RRASRas-related protein R-Ras. (218 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (323 aa)
FMN1Formin-1 isoform X1. (1420 aa)
BCL2Apoptosis regulator Bcl-2. (232 aa)
PDPNPodoplanin. (161 aa)
SKAP1Src kinase-associated phosphoprotein 1. (265 aa)
AGR2Anterior gradient protein 2 homolog isoform X1. (175 aa)
NEDD9Enhancer of filamentation 1-like. (819 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
MFI2Melanotransferrin; Belongs to the transferrin family. (739 aa)
APODApolipoprotein D. (213 aa)
LOC103071971Collagen alpha-1(I) chain-like. (1463 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog. (668 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
RREB1Ras-responsive element-binding protein 1. (1774 aa)
LOC103088938N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A-like. (313 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PLET1Placenta-expressed transcript 1 protein. (328 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
EPHA1Ephrin type-A receptor 1. (981 aa)
HOXA7Homeobox protein Hox-A7. (233 aa)
JUPJunction plakoglobin. (330 aa)
LOC103089209N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B-like. (321 aa)
RELL2RELT-like protein 2. (303 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1. (1351 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
LOC103088671N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C-like. (333 aa)
EPHA3Ephrin type-A receptor 3-like isoform X1. (984 aa)
COL16A1Collagen alpha-1(XVI) chain. (1612 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
PLAUUrokinase-type plasminogen activator isoform X1. (440 aa)
CALRCalreticulin. (415 aa)
EPB41L5LOW QUALITY PROTEIN: band 4.1-like protein 5. (505 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ECM2Extracellular matrix protein 2 isoform X1. (685 aa)
VWC2Brorin. (321 aa)
VCLVinculin isoform X1. (1134 aa)
FOXF1Forkhead box protein F1. (377 aa)
EGFLAMPikachurin isoform X5. (1018 aa)
PLEKHA2Pleckstrin homology domain-containing family A member 2. (574 aa)
LOC103090986Target of Nesh-SH3-like. (1239 aa)
COL26A1Collagen alpha-1(XXVI) chain. (436 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (282 aa)
LDB1LIM domain-binding protein 1 isoform X1. (411 aa)
LOC103083182Pleckstrin homology-like domain family B member 2-like. (938 aa)
VITLOW QUALITY PROTEIN: vitrin. (656 aa)
ANGPT2Angiopoietin-2. (496 aa)
ACTN4Alpha-actinin-4 isoform X1. (933 aa)
LOC103091262Target of Nesh-SH3-like. (209 aa)
FERMT1Fermitin family homolog 1 isoform X1. (693 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1744 aa)
EMILIN1EMILIN-1. (1015 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
SLKSTE20-like serine/threonine-protein kinase isoform X1. (1240 aa)
EGFL6LOW QUALITY PROTEIN: EGF-like-domain, multiple 6. (321 aa)
CCL21c-C motif chemokine 21. (131 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
BST1LOW QUALITY PROTEIN: bone marrow stromal cell antigen 1. (314 aa)
MYADMLOW QUALITY PROTEIN: myeloid-associated differentiation marker. (316 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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