14 items (Lipotes vexillifer) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	DCLRE1B	5' exonuclease Apollo. (539 aa)
	TERF2IP	Telomeric repeat-binding factor 2-interacting protein 1. (399 aa)
	PRKDC	DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4131 aa)
	DCLRE1C	Protein artemis. (710 aa)
	RAD50	DNA repair protein RAD50 isoform X1. (1312 aa)
	ACD	Adrenocortical dysplasia protein homolog. (454 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa)
	MRE11A	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
	TERF2	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (539 aa)
	POT1	Protection of telomeres protein 1. (785 aa)
	TINF2	TERF1-interacting nuclear factor 2. (453 aa)
	NBN	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (749 aa)
	DCLRE1A	DNA cross-link repair 1A protein. (1054 aa)
	OBFC1	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD	OBFC1	A0A340X7K8	A0A340YBQ9	Adrenocortical dysplasia protein homolog.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.787
ACD	POT1	A0A340X7K8	A0A340WMS3	Adrenocortical dysplasia protein homolog.	Protection of telomeres protein 1.	0.996
ACD	TERF1	A0A340X7K8	A0A340WXK3	Adrenocortical dysplasia protein homolog.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.923
ACD	TERF2	A0A340X7K8	A0A340WQR7	Adrenocortical dysplasia protein homolog.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.985
ACD	TERF2IP	A0A340X7K8	A0A340XS01	Adrenocortical dysplasia protein homolog.	Telomeric repeat-binding factor 2-interacting protein 1.	0.980
ACD	TINF2	A0A340X7K8	A0A340WLN7	Adrenocortical dysplasia protein homolog.	TERF1-interacting nuclear factor 2.	0.996
DCLRE1A	DCLRE1B	A0A340YE29	A0A340XT76	DNA cross-link repair 1A protein.	5' exonuclease Apollo.	0.435
DCLRE1A	MRE11A	A0A340YE29	A0A340WRY2	DNA cross-link repair 1A protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.614
DCLRE1A	NBN	A0A340YE29	A0A340WFM1	DNA cross-link repair 1A protein.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.541
DCLRE1A	PRKDC	A0A340YE29	A0A340XRV8	DNA cross-link repair 1A protein.	DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family.	0.520
DCLRE1A	RAD50	A0A340YE29	A0A340XJ04	DNA cross-link repair 1A protein.	DNA repair protein RAD50 isoform X1.	0.480
DCLRE1A	TERF2	A0A340YE29	A0A340WQR7	DNA cross-link repair 1A protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.710
DCLRE1A	TERF2IP	A0A340YE29	A0A340XS01	DNA cross-link repair 1A protein.	Telomeric repeat-binding factor 2-interacting protein 1.	0.540
DCLRE1B	DCLRE1A	A0A340XT76	A0A340YE29	5' exonuclease Apollo.	DNA cross-link repair 1A protein.	0.435
DCLRE1B	MRE11A	A0A340XT76	A0A340WRY2	5' exonuclease Apollo.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.604
DCLRE1B	NBN	A0A340XT76	A0A340WFM1	5' exonuclease Apollo.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.541
DCLRE1B	POT1	A0A340XT76	A0A340WMS3	5' exonuclease Apollo.	Protection of telomeres protein 1.	0.459
DCLRE1B	PRKDC	A0A340XT76	A0A340XRV8	5' exonuclease Apollo.	DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family.	0.533
DCLRE1B	RAD50	A0A340XT76	A0A340XJ04	5' exonuclease Apollo.	DNA repair protein RAD50 isoform X1.	0.480
DCLRE1B	TERF1	A0A340XT76	A0A340WXK3	5' exonuclease Apollo.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.513