STRINGSTRING
HDAC10 HDAC10 HDAC4 HDAC4 HDAC3 HDAC3 NDST2 NDST2 HDAC1 HDAC1 LOC103072627 LOC103072627 HDAC8 HDAC8 SIRT3 SIRT3 NDST3 NDST3 SIRT2 SIRT2 HDAC7 HDAC7 MACROD1 MACROD1 SIRT7 SIRT7 MTA2 MTA2 HDAC9 HDAC9 SIRT6 SIRT6 PIGL PIGL MIER2 MIER2 MIER1 MIER1 OARD1 OARD1 SIRT1 SIRT1 SUDS3 SUDS3 CCDC96 CCDC96 HDAC5 HDAC5 NDST4 NDST4 LOC103088729 LOC103088729 ADPRHL2 ADPRHL2 AMDHD2 AMDHD2 LOC103070262 LOC103070262 HDAC6 HDAC6 HDAC2 HDAC2 YDJC YDJC SIRT4 SIRT4 NDST1 NDST1 HDAC11 HDAC11 SIRT5 SIRT5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDAC10Histone deacetylase 10. (668 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1148 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
NDST2Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2. (883 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (538 aa)
LOC103072627Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2-like. (365 aa)
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (415 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (334 aa)
NDST3Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3. (887 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (946 aa)
MACROD1O-acetyl-ADP-ribose deacetylase MACROD1. (325 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7. (400 aa)
MTA2Metastasis-associated protein MTA2. (666 aa)
HDAC9Histone deacetylase 9-like isoform X6. (589 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (359 aa)
PIGLN-acetylglucosaminyl-phosphatidylinositol de-N-acetylase. (253 aa)
MIER2Mesoderm induction early response protein 2. (684 aa)
MIER1Mesoderm induction early response protein 1 isoform X1. (578 aa)
OARD1O-acetyl-ADP-ribose deacetylase 1 isoform X1. (152 aa)
SIRT1LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa)
SUDS3Sin3 histone deacetylase corepressor complex component SDS3. (328 aa)
CCDC96Coiled-coil domain-containing protein 96. (545 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1127 aa)
NDST4Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4-like. (872 aa)
LOC103088729Histone deacetylase 9-like. (277 aa)
ADPRHL2poly(ADP-ribose) glycohydrolase ARH3. (365 aa)
AMDHD2LOW QUALITY PROTEIN: putative N-acetylglucosamine-6-phosphate deacetylase. (445 aa)
LOC103070262Sin3 histone deacetylase corepressor complex component SDS3-like. (328 aa)
HDAC6Histone deacetylase 6. (1142 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
YDJCUPF0249 protein ydjC homolog. (323 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X1. (882 aa)
HDAC11Histone deacetylase 11. (266 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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