STRINGSTRING
CCNB3 CCNB3 SMCR8 SMCR8 CCNL2 CCNL2 PARP16 PARP16 CCNH CCNH MAP2K1 MAP2K1 CCNL1 CCNL1 GCN1L1 GCN1L1 MBIP MBIP CDKN2A CDKN2A LOC103085642 LOC103085642 LOC103069874 LOC103069874 QARS QARS KIDINS220 KIDINS220 TRIB2 TRIB2 NCK1 NCK1 FAM58A FAM58A SH3BP5L SH3BP5L DDX3X DDX3X TGFA TGFA NKPD1 NKPD1 TRIB1 TRIB1 CCNJ CCNJ LOC103088902 LOC103088902 BMPR1A BMPR1A STRADA STRADA INCA1 INCA1 SOWAHB SOWAHB PRKAR1A PRKAR1A DUS2 DUS2 CCNB1 CCNB1 CDKN2B CDKN2B GPRC5A GPRC5A CCNI CCNI GPRC5D GPRC5D PKIA PKIA LOC103088461 LOC103088461 CCNG1 CCNG1 PKIB PKIB CKS2 CKS2 FGFR1OP FGFR1OP LOC103086683 LOC103086683 MOB1B MOB1B GSKIP GSKIP TCL1B TCL1B CNPPD1 CNPPD1 CDK5R2 CDK5R2 PRKAG3 PRKAG3 IBTK IBTK TOM1L1 TOM1L1 PRKAR2A PRKAR2A ERCC6 ERCC6 TCL1A TCL1A SPDYA SPDYA AFAP1L2 AFAP1L2 ABI1 ABI1 WNK1 WNK1 IQGAP1 IQGAP1 DNAJC3 DNAJC3 CCNO CCNO ITPRIP ITPRIP BMP2 BMP2 CCNE1 CCNE1 PRKRIP1 PRKRIP1 HSPB1 HSPB1 ALS2 ALS2 LTF LTF ERBB4 ERBB4 CCND2 CCND2 NCKAP1L NCKAP1L PRKAG2 PRKAG2 STRADB STRADB CDKN1A CDKN1A CAMK2N2 CAMK2N2 MTCP1 MTCP1 EPO EPO FAM150B FAM150B LOC103069433 LOC103069433 BMPR2 BMPR2 ERBB3 ERBB3 RGCC RGCC PRKAR1B PRKAR1B SPRY4 SPRY4 CAB39L CAB39L FAM212A FAM212A DAB2IP DAB2IP CDKN1C CDKN1C IGF2 IGF2 CCND1 CCND1 DGKQ DGKQ RPLP1 RPLP1 RICTOR RICTOR ELP3 ELP3 SPRY3 SPRY3 NRG1 NRG1 PIK3CA PIK3CA CIT CIT ITPRIPL2 ITPRIPL2 GPRC5B GPRC5B SPRY2 SPRY2 CCNJL CCNJL ANGPT4 ANGPT4 CCNA1 CCNA1 GAS6 GAS6 ETAA1 ETAA1 MOB3C MOB3C MOB2 MOB2 YWHAB YWHAB PKIG PKIG PAK2 PAK2 CCNC CCNC EGF EGF NCAPG2 NCAPG2 TAL1 TAL1 CAB39 CAB39 CCNYL1 CCNYL1 TRIB3 TRIB3 CCNT1 CCNT1 DAZAP2 DAZAP2 HEXIM2 HEXIM2 ANKRD54 ANKRD54 MOB3B MOB3B KIAA0141 KIAA0141 GPRC5C GPRC5C PRKAR2B PRKAR2B CCNE2 CCNE2 STAP1 STAP1 CCNY CCNY DBF4B DBF4B CCNT2 CCNT2 MNAT1 MNAT1 PARVA PARVA CIB1 CIB1 KAT2B KAT2B SH3BP5 SH3BP5 CDKN1B CDKN1B ALK ALK CCNA2 CCNA2 ARMC9 ARMC9 RAC2 RAC2 MOB1A MOB1A CAMK2N1 CAMK2N1 CD40LG CD40LG IGF1 IGF1 GHRL GHRL MAP3K13 MAP3K13 HYAL2 HYAL2 CCNK CCNK LOC103086712 LOC103086712 APC APC CDK5R1 CDK5R1 PRKAG1 PRKAG1 FAM212B FAM212B LOC103081641 LOC103081641 P2RX7 P2RX7 DBF4 DBF4 HEXIM1 HEXIM1 CCNG2 CCNG2 FAM20A FAM20A MLST8 MLST8 CCNF CCNF RPTOR RPTOR BMPR1B BMPR1B EPGN EPGN BTC BTC INCENP INCENP FAM150A FAM150A CCNI2 CCNI2 EGFR EGFR LOC103090158 LOC103090158 EREG EREG AREG AREG GNB2L1 GNB2L1 CDC37 CDC37 STK11 STK11 LTK LTK GREM1 GREM1 ELP4 ELP4 CDKN2C CDKN2C CDKN2D CDKN2D MAP2K2 MAP2K2 WNT11 WNT11 MOB3A MOB3A SPRED1 SPRED1 HBEGF HBEGF LOC103079324 LOC103079324 TGFB1 TGFB1 CSNK2B CSNK2B DAXX DAXX CCND3 CCND3 CKS1B CKS1B CCNB2 CCNB2 CNTD2 CNTD2 LOC103088826 LOC103088826
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNB3LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1367 aa)
SMCR8LOW QUALITY PROTEIN: smith-Magenis syndrome chromosomal region candidate gene 8 protein. (943 aa)
CCNL2cyclin-L2 isoform X1; Belongs to the cyclin family. (525 aa)
PARP16Poly [ADP-ribose] polymerase. (322 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (330 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
CCNL1cyclin-L1 isoform X1; Belongs to the cyclin family. (527 aa)
GCN1L1Translational activator GCN1. (2671 aa)
MBIPMAP3K12-binding inhibitory protein 1 isoform X1. (344 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A, isoforms 1/2/3. (152 aa)
LOC103085642Protein GVQW1-like. (121 aa)
LOC103069874Abl interactor 1-like. (235 aa)
QARSLOW QUALITY PROTEIN: glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (793 aa)
KIDINS220Kinase D-interacting substrate of 220 kDa. (1769 aa)
TRIB2Tribbles homolog 2 isoform X1. (343 aa)
NCK1Cytoplasmic protein. (377 aa)
FAM58ACyclin-related protein FAM58A isoform X1; Belongs to the cyclin family. (202 aa)
SH3BP5LSH3 domain-binding protein 5-like. (384 aa)
DDX3XATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (662 aa)
TGFAProtransforming growth factor alpha. (145 aa)
NKPD1NTPase KAP family P-loop domain-containing protein 1. (871 aa)
TRIB1Tribbles homolog 1. (372 aa)
CCNJcyclin-J isoform X1; Belongs to the cyclin family. (383 aa)
LOC103088902Probable glutamine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (424 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
STRADASTE20-related kinase adapter protein alpha isoform X1. (431 aa)
INCA1Protein INCA1. (280 aa)
SOWAHBAnkyrin repeat domain-containing protein SOWAHB. (807 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
DUS2tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X1. (493 aa)
CCNB1G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (131 aa)
GPRC5ARetinoic acid-induced protein 3. (357 aa)
CCNIcyclin-I isoform X1; Belongs to the cyclin family. (377 aa)
GPRC5DLOW QUALITY PROTEIN: G-protein coupled receptor family C group 5 member D. (375 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (92 aa)
LOC103088461Actin filament-associated protein 1-like 2-like. (190 aa)
CCNG1cyclin-G1 isoform X1; Belongs to the cyclin family. (295 aa)
PKIBcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (78 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
FGFR1OPFGFR1 oncogene partner isoform X1. (399 aa)
LOC103086683Probable glutamine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (587 aa)
MOB1BMOB kinase activator 1B. (216 aa)
GSKIPGSK3-beta interaction protein. (139 aa)
TCL1BT-cell leukemia/lymphoma protein 1B. (128 aa)
CNPPD1Protein CNPPD1 isoform X1. (453 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (369 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X3. (482 aa)
IBTKLOW QUALITY PROTEIN: inhibitor of Bruton tyrosine kinase. (1360 aa)
TOM1L1TOM1-like protein 1 isoform X1; Belongs to the TOM1 family. (476 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit isoform X1. (401 aa)
ERCC6DNA excision repair protein ERCC-6. (1485 aa)
TCL1AT-cell leukemia/lymphoma protein 1A. (115 aa)
SPDYASpeedy protein A. (312 aa)
AFAP1L2Actin filament-associated protein 1-like 2. (655 aa)
ABI1Abl interactor 1-like isoform X1. (379 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2636 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1627 aa)
DNAJC3dnaJ homolog subfamily C member 3. (504 aa)
CCNOcyclin-O; Belongs to the cyclin family. (348 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor-interacting protein. (556 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
PRKRIP1PRKR-interacting protein 1. (184 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
ALS2Alsin-like. (527 aa)
LTFLactotransferrin isoform X2; Belongs to the transferrin family. (730 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa)
STRADBSTE20-related kinase adapter protein beta isoform X1. (418 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (164 aa)
CAMK2N2Calcium/calmodulin-dependent protein kinase II inhibitor 2. (79 aa)
MTCP1Protein p13 MTCP-1. (107 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
FAM150BProtein FAM150B. (152 aa)
LOC103069433Alsin-like. (1113 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
RGCCRegulator of cell cycle RGCC. (137 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit isoform X1. (381 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
CAB39LCalcium-binding protein 39-like isoform X1. (337 aa)
FAM212AProtein FAM212A. (283 aa)
DAB2IPLOW QUALITY PROTEIN: disabled homolog 2-interacting protein. (1173 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (257 aa)
IGF2Insulin-like growth factor II isoform X1. (237 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
DGKQDiacylglycerol kinase. (937 aa)
RPLP160S acidic ribosomal protein P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa)
RICTORRapamycin-insensitive companion of mTOR-like isoform X1. (1580 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
SPRY3Protein sprouty homolog 3. (288 aa)
NRG1Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (641 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1976 aa)
ITPRIPL2Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa)
GPRC5BG-protein coupled receptor family C group 5 member B isoform X1. (386 aa)
SPRY2Protein sprouty homolog 2 isoform X1. (315 aa)
CCNJLcyclin-J-like protein; Belongs to the cyclin family. (425 aa)
ANGPT4Angiopoietin-4. (498 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (421 aa)
GAS6Growth arrest-specific protein 6. (540 aa)
ETAA1Ewing's tumor-associated antigen 1 homolog. (905 aa)
MOB3CMOB kinase activator 3C isoform X1. (216 aa)
MOB2MOB kinase activator 2. (264 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
PKIGcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
CCNCcyclin-C isoform X1; Belongs to the cyclin family. (283 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
NCAPG2Condensin-2 complex subunit G2. (1140 aa)
TAL1T-cell acute lymphocytic leukemia protein 1. (318 aa)
CAB39Calcium-binding protein 39. (373 aa)
CCNYL1cyclin-Y-like protein 1 isoform X1; Belongs to the cyclin family. (363 aa)
TRIB3LOW QUALITY PROTEIN: tribbles homolog 3. (349 aa)
CCNT1cyclin-T1; Belongs to the cyclin family. (727 aa)
DAZAP2DAZ-associated protein 2 isoform X1. (207 aa)
HEXIM2Protein HEXIM2. (236 aa)
ANKRD54Ankyrin repeat domain-containing protein 54. (299 aa)
MOB3BMOB kinase activator 3B. (216 aa)
KIAA0141Death ligand signal enhancer. (517 aa)
GPRC5CG-protein coupled receptor family C group 5 member C isoform X1. (442 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (415 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa)
STAP1LOW QUALITY PROTEIN: signal transducing adaptor family member 1. (231 aa)
CCNYcyclin-Y-like isoform X1; Belongs to the cyclin family. (311 aa)
DBF4BLOW QUALITY PROTEIN: DBF4 zinc finger B. (780 aa)
CCNT2LOW QUALITY PROTEIN: cyclin T2; Belongs to the cyclin family. (669 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PARVAAlpha-parvin. (412 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
KAT2BHistone acetyltransferase KAT2B. (735 aa)
SH3BP5SH3 domain-binding protein 5. (452 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
ALKTyrosine-protein kinase receptor. (1619 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
ARMC9lisH domain-containing protein ARMC9 isoform X1. (853 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
MOB1AMOB kinase activator 1A isoform X1. (216 aa)
CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1. (78 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
IGF1Insulin-like growth factor I isoform X1. (174 aa)
GHRLAppetite-regulating hormone isoform X1. (141 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (968 aa)
HYAL2Hyaluronidase. (476 aa)
CCNKcyclin-K; Belongs to the cyclin family. (524 aa)
LOC10308671260S acidic ribosomal protein P1-like isoform X1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa)
APCAdenomatous polyposis coli protein isoform X1. (2847 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (336 aa)
FAM212BProtein FAM212B. (288 aa)
LOC103081641LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6-like; Belongs to the protein kinase superfamily. (394 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
DBF4Protein DBF4 homolog A isoform X1. (680 aa)
HEXIM1Protein HEXIM1 isoform X1. (347 aa)
CCNG2cyclin-G2; Belongs to the cyclin family. (344 aa)
FAM20AProtein FAM20A. (521 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X1. (326 aa)
CCNFcyclin-F; Belongs to the cyclin family. (785 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1335 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
EPGNEpigen isoform X1. (153 aa)
BTCProbetacellulin. (178 aa)
INCENPInner centromere protein. (945 aa)
FAM150AProtein FAM150A. (131 aa)
CCNI2cyclin-I2; Belongs to the cyclin family. (260 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
LOC103090158Uncharacterized protein LOC103090158; Belongs to the eukaryotic ribosomal protein P1/P2 family. (238 aa)
EREGProepiregulin. (163 aa)
AREGAmphiregulin isoform X1. (254 aa)
GNB2L1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
CDC37Hsp90 co-chaperone Cdc37. (379 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (438 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (858 aa)
GREM1Gremlin. (184 aa)
ELP4Elongator complex protein 4 isoform X1. (474 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (166 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
MOB3AMOB kinase activator 3A. (217 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (443 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
LOC103079324Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa)
DAXXDeath domain-associated protein 6. (757 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (358 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa)
CNTD2LOW QUALITY PROTEIN: cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (339 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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