STRINGSTRING
DVL1 DVL1 PTPRN PTPRN ACVR1C ACVR1C SYK SYK TRPV4 TRPV4 EDN1 EDN1 FZD4 FZD4 CPLX3 CPLX3 STXBP3 STXBP3 P2RX7 P2RX7 ABCA1 ABCA1 TMF1 TMF1 MC4R MC4R GHRH GHRH HNF1A HNF1A WNK4 WNK4 RAP1A RAP1A PTGS2 PTGS2 LOC103079561 LOC103079561 GPR119 GPR119 SLC16A10 SLC16A10 ERC2 ERC2 SYN3 SYN3 ASIC1 ASIC1 NF1 NF1 SMPD3 SMPD3 SNAP25 SNAP25 CPLX4 CPLX4 SYT1 SYT1 STX11 STX11 PORCN PORCN FAM3B FAM3B SNAP29 SNAP29 ILDR1 ILDR1 NOS2 NOS2 CDK16 CDK16 SYN1 SYN1 SYN2 SYN2 LOC103089855 LOC103089855 SLC30A8 SLC30A8 NT5DC2 NT5DC2 STX1B STX1B PRRT2 PRRT2 DOC2A DOC2A CADPS CADPS STX4 STX4 PARK7 PARK7 RIMS3 RIMS3 UNC13B UNC13B DOC2B DOC2B P2RX1 P2RX1 RPH3AL RPH3AL NT5DC3 NT5DC3 ANXA1 ANXA1 STX2 STX2 FKBP1B FKBP1B STX3 STX3 EXOC3L1 EXOC3L1 LIN7A LIN7A SYT2 SYT2 VAMP2 VAMP2 SNAPIN SNAPIN LOC103085888 LOC103085888 RIMS1 RIMS1 SNAP47 SNAP47 SNX19 SNX19 ADCYAP1 ADCYAP1 ILDR2 ILDR2 SLC44A4 SLC44A4 VIP VIP UBE2Q1 UBE2Q1 PINK1 PINK1 LRRC1 LRRC1 RAPGEF4 RAPGEF4 RAB3A RAB3A LTBP4 LTBP4 PSEN1 PSEN1 PRKCE PRKCE ABCA2 ABCA2 LOC103078014 LOC103078014 RAB11B RAB11B WLS WLS SNAP23 SNAP23 SYT9 SYT9 UNC13A UNC13A STXBP2 STXBP2 UNC13C UNC13C RBM4 RBM4 NEUROD1 NEUROD1 LIN7B LIN7B SV2A SV2A RAF1 RAF1 LOC103090072 LOC103090072 LIN7C LIN7C PTPRN2 PTPRN2 PPFIA3 PPFIA3 SCRIB SCRIB NLGN1 NLGN1 HNF1B HNF1B STX19 STX19 RAB1A RAB1A LOC103084351 LOC103084351 CPLX2 CPLX2 RIMS2 RIMS2 MAFA MAFA GHSR GHSR RAB44 RAB44 GATA3 GATA3 KCNQ1 KCNQ1 EDNRB EDNRB LOC103082357 LOC103082357 AQP1 AQP1 SYT8 SYT8 GHRHR GHRHR INHBA INHBA STX1A STX1A BRAF BRAF TRPV6 TRPV6 DGKI DGKI RPH3A RPH3A PDZD11 PDZD11 RAB11FIP2 RAB11FIP2 SYT5 SYT5 LEP LEP CTBP2 CTBP2 LOC103081195 LOC103081195 FFAR1 FFAR1 CREB1 CREB1 FAM129B FAM129B CPE CPE FFAR4 FFAR4 HIF1A HIF1A STXBP1 STXBP1 OTOF OTOF SUCNR1 SUCNR1 VGF VGF CADPS2 CADPS2 PDX1 PDX1 GPR68 GPR68
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X2. (699 aa)
PTPRNReceptor-type tyrosine-protein phosphatase-like N isoform X1. (979 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
EDN1Endothelin-1. (202 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CPLX3Complexin-3. (158 aa)
STXBP3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2261 aa)
TMF1TATA element modulatory factor. (1093 aa)
MC4RMelanocortin receptor 4. (332 aa)
GHRHSomatoliberin isoform X1. (106 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (632 aa)
WNK4Serine/threonine-protein kinase WNK4. (1232 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
PTGS2Prostaglandin G/H synthase 2 isoform X2. (604 aa)
LOC103079561LOW QUALITY PROTEIN: double C2-like domain-containing protein gamma-like. (425 aa)
GPR119Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (335 aa)
SLC16A10Monocarboxylate transporter 10. (519 aa)
ERC2ERC protein 2. (854 aa)
SYN3Synapsin-3 isoform X2. (580 aa)
ASIC1Acid-sensing ion channel 1 isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (574 aa)
NF1Neurofibromin isoform X1. (2841 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (654 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
CPLX4Complexin-4. (159 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
STX11Syntaxin-11; Belongs to the syntaxin family. (287 aa)
PORCNProtein-cysteine N-palmitoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family. (461 aa)
FAM3BProtein FAM3B. (235 aa)
SNAP29Synaptosomal-associated protein 29. (258 aa)
ILDR1Immunoglobulin-like domain-containing receptor 1 isoform X1. (550 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1157 aa)
CDK16Cyclin-dependent kinase 16 isoform X1; Belongs to the protein kinase superfamily. (496 aa)
SYN1Synapsin-1 isoform X1. (706 aa)
SYN2Synapsin-2. (582 aa)
LOC103089855LOW QUALITY PROTEIN: selenoprotein M-like. (142 aa)
SLC30A8LOW QUALITY PROTEIN: zinc transporter 8. (345 aa)
NT5DC25'-nucleotidase domain-containing protein 2 isoform X1. (486 aa)
STX1Bsyntaxin-1B isoform X2; Belongs to the syntaxin family. (291 aa)
PRRT2LOW QUALITY PROTEIN: proline-rich transmembrane protein 2. (411 aa)
DOC2ADouble C2-like domain-containing protein alpha isoform X1. (428 aa)
CADPSCalcium-dependent secretion activator 1 isoform X6. (1348 aa)
STX4Syntaxin-4; Belongs to the syntaxin family. (297 aa)
PARK7Protein DJ-1. (189 aa)
RIMS3Regulating synaptic membrane exocytosis protein 3. (308 aa)
UNC13BProtein unc-13 homolog B isoform X1. (1609 aa)
DOC2BDouble C2-like domain-containing protein. (412 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
RPH3ALRab effector Noc2. (289 aa)
NT5DC35'-nucleotidase domain-containing protein 3. (549 aa)
ANXA1Annexin. (346 aa)
STX2Syntaxin-2; Belongs to the syntaxin family. (259 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
STX3Syntaxin-3; Belongs to the syntaxin family. (289 aa)
EXOC3L1Exocyst complex component 3-like protein. (739 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
SYT2Synaptotagmin-2 isoform X1. (422 aa)
VAMP2Vesicle-associated membrane protein 2. (116 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LOC103085888Corticotropin-releasing factor receptor 1-like. (129 aa)
RIMS1Regulating synaptic membrane exocytosis protein 1-like isoform X1. (1678 aa)
SNAP47LOW QUALITY PROTEIN: synaptosomal-associated protein 47. (491 aa)
SNX19Sorting nexin-19. (1005 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide isoform X1. (176 aa)
ILDR2LOW QUALITY PROTEIN: immunoglobulin-like domain-containing receptor 2. (649 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (706 aa)
VIPVIP peptides isoform X1. (170 aa)
UBE2Q1Ubiquitin-conjugating enzyme E2 Q1. (383 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (571 aa)
LRRC1Leucine-rich repeat-containing protein 1. (524 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4 isoform X1. (1011 aa)
RAB3ARas-related protein Rab-3A. (220 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1628 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. (493 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2570 aa)
LOC103078014Protein unc-13 homolog C-like. (782 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
WLSProtein wntless homolog isoform X1. (541 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
SYT9Synaptotagmin-9. (589 aa)
UNC13AProtein unc-13 homolog A. (1843 aa)
STXBP2Syntaxin-binding protein 2 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (606 aa)
UNC13CProtein unc-13 homolog C. (1426 aa)
RBM4RNA-binding protein 4 isoform X1. (363 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC103090072Cyclic AMP-responsive element-binding protein 1-like. (47 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
PTPRN2Receptor-type tyrosine-protein phosphatase N2. (1042 aa)
PPFIA3Liprin-alpha-3. (1194 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1659 aa)
NLGN1Neuroligin-1 isoform X1. (863 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X1. (557 aa)
STX19Syntaxin-19. (294 aa)
RAB1ARas-related protein Rab-1A isoform X1. (205 aa)
LOC103084351LOW QUALITY PROTEIN: T-box transcription factor TBX3-like. (737 aa)
CPLX2Complexin-2. (134 aa)
RIMS2Regulating synaptic membrane exocytosis protein 2 isoform X1. (1557 aa)
MAFATranscription factor MafA. (335 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
RAB44Ras-related protein Rab-44. (931 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
EDNRBEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC103082357Cytochrome b5 reductase 4-like. (520 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SYT8Synaptotagmin-8. (360 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (452 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (721 aa)
DGKIDiacylglycerol kinase. (1078 aa)
RPH3Arabphilin-3A isoform X1. (703 aa)
PDZD11PDZ domain-containing protein 11. (174 aa)
RAB11FIP2Rab11 family-interacting protein 2. (513 aa)
SYT5Synaptotagmin-5 isoform X1. (386 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CTBP2C-terminal-binding protein 2-like isoform X1. (983 aa)
LOC103081195Uncharacterized protein C10orf118 homolog. (908 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
FAM129BNiban-like protein 1. (748 aa)
CPECarboxypeptidase E. (475 aa)
FFAR4Free fatty acid receptor 4 isoform X1. (360 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
OTOFOtoferlin isoform X1. (1990 aa)
SUCNR1LOW QUALITY PROTEIN: succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
VGFLOW QUALITY PROTEIN: VGF nerve growth factor inducible. (604 aa)
CADPS2Calcium-dependent secretion activator 2. (1190 aa)
PDX1Pancreas/duodenum homeobox protein 1. (286 aa)
GPR68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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