22 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAX8	Paired box protein Pax-8. (288 aa)
	EDN1	Endothelin-1. (202 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
	MAPK1	Mitogen-activated protein kinase 1 isoform X1. (263 aa)
	HESX1	Homeobox expressed in ES cells 1. (186 aa)
	HOXD3	Homeobox protein Hox-D3. (432 aa)
	MAPK3	Mitogen-activated protein kinase. (325 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
	SRF	Serum response factor. (510 aa)
	LOC103079308	Uncharacterized protein LOC103079308. (289 aa)
	FOXE1	Forkhead box protein E1. (373 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
	LOC103077930	Thyroid transcription factor 1-like isoform X2. (402 aa)
	NKX2-5	Homeobox protein Nkx-2.5. (324 aa)
	HOXA3	Homeobox protein Hox-A3. (385 aa)
	HOXA5	Homeobox protein Hox-A5. (270 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	EDNRA	Endothelin-1 receptor isoform X2. (318 aa)
	SIX1	Homeobox protein SIX1. (284 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (763 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	MAP2K1	A0A340Y5C2	A0A340WM60	Serine/threonine-protein kinase B-raf.	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily.	0.987
BRAF	MAPK1	A0A340Y5C2	A0A340WNH5	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase 1 isoform X1.	0.855
BRAF	MAPK3	A0A340Y5C2	A0A340WYU9	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase.	0.854
BRAF	PAX8	A0A340Y5C2	A0A340W9H9	Serine/threonine-protein kinase B-raf.	Paired box protein Pax-8.	0.439
BRAF	RAF1	A0A340Y5C2	A0A340XQI5	Serine/threonine-protein kinase B-raf.	RAF proto-oncogene serine/threonine-protein kinase isoform X1.	0.992
EDN1	EDNRA	A0A340WFW5	A0A340YEF3	Endothelin-1.	Endothelin-1 receptor isoform X2.	0.996
EDNRA	EDN1	A0A340YEF3	A0A340WFW5	Endothelin-1 receptor isoform X2.	Endothelin-1.	0.996
FGF10	FGF8	A0A340XK40	A0A340YDC6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.539
FGF10	LOC103077930	A0A340XK40	A0A340XTJ0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Thyroid transcription factor 1-like isoform X2.	0.491
FGF10	LOC103079308	A0A340XK40	A0A340XDR9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein LOC103079308.	0.684
FGF10	SHH	A0A340XK40	A0A340X6Q8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.684
FGF8	FGF10	A0A340YDC6	A0A340XK40	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.539
FGF8	LOC103079308	A0A340YDC6	A0A340XDR9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein LOC103079308.	0.695
FGF8	SHH	A0A340YDC6	A0A340X6Q8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.695
FOXE1	LOC103077930	A0A340XJX6	A0A340XTJ0	Forkhead box protein E1.	Thyroid transcription factor 1-like isoform X2.	0.633
FOXE1	PAX8	A0A340XJX6	A0A340W9H9	Forkhead box protein E1.	Paired box protein Pax-8.	0.643
HOXA3	HOXA5	A0A340Y3F4	A0A340Y3U1	Homeobox protein Hox-A3.	Homeobox protein Hox-A5.	0.481
HOXA5	HOXA3	A0A340Y3U1	A0A340Y3F4	Homeobox protein Hox-A5.	Homeobox protein Hox-A3.	0.481
LOC103077930	FGF10	A0A340XTJ0	A0A340XK40	Thyroid transcription factor 1-like isoform X2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.491
LOC103077930	FOXE1	A0A340XTJ0	A0A340XJX6	Thyroid transcription factor 1-like isoform X2.	Forkhead box protein E1.	0.633