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DDX58 DDX58 IL1B IL1B SYK SYK CARD9 CARD9 RASGRP1 RASGRP1 IL12B IL12B LOC103073060 LOC103073060 IL23A IL23A ISL1 ISL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX58LOW QUALITY PROTEIN: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58. (886 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
CARD9Caspase recruitment domain-containing protein 9. (539 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (797 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC103073060Synaptopodin 2-like protein-like. (392 aa)
IL23AInterleukin-23 subunit alpha. (187 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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