STRINGSTRING
WT1 WT1 SALL1 SALL1 LOC103088826 LOC103088826 GIPR GIPR LOC103079308 LOC103079308 HES1 HES1 WNT5A WNT5A SRF SRF NR0B1 NR0B1 BMPR1A BMPR1A LOC103085888 LOC103085888 SHH SHH ANXA1 ANXA1 NEUROG3 NEUROG3 PAX1 PAX1 PDGFRA PDGFRA PDPK1 PDPK1 CDH2 CDH2 ONECUT2 ONECUT2 ARMC5 ARMC5 RFX6 RFX6 NKX2-2 NKX2-2 LOC103070818 LOC103070818 FOXA2 FOXA2 DRD2 DRD2 MAPK3 MAPK3 SOX9 SOX9 ASCL1 ASCL1 HOXD3 HOXD3 HESX1 HESX1 NF1 NF1 NR5A1 NR5A1 CRKL CRKL LOC103085851 LOC103085851 GATA6 GATA6 MAPK1 MAPK1 BHLHA15 BHLHA15 MAP2K1 MAP2K1 ARID5B ARID5B GDF11 GDF11 SIDT2 SIDT2 LOC103087126 LOC103087126 STRA6 STRA6 SMAD3 SMAD3 EDN1 EDN1 DLL1 DLL1 PAX8 PAX8 BMP4 BMP4 GHRH GHRH CITED2 CITED2 GIP GIP NKX2-5 NKX2-5 BMP6 BMP6 POU3F2 POU3F2 LOC103088309 LOC103088309 NOG NOG HNF4A HNF4A LOC103077930 LOC103077930 LOC103090072 LOC103090072 RAF1 RAF1 LOC103086063 LOC103086063 PDX1 PDX1 DKK3 DKK3 LOC103078457 LOC103078457 SLC6A3 SLC6A3 BMP5 BMP5 VHL VHL PAX4 PAX4 SIX1 SIX1 MNX1 MNX1 EDNRA EDNRA ISL1 ISL1 SMO SMO FGF8 FGF8 GSX1 GSX1 NKX6-1 NKX6-1 PITX1 PITX1 ONECUT1 ONECUT1 CDK6 CDK6 APOA1 APOA1 FGF10 FGF10 WNT11 WNT11 TGFBR1 TGFBR1 FOXE1 FOXE1 LHX3 LHX3 PAX6 PAX6 CREB1 CREB1 BMP2 BMP2 FGF2 FGF2 BRAF BRAF EIF2AK3 EIF2AK3 NEUROD1 NEUROD1 GCM2 GCM2 GHRHR GHRHR HOXA5 HOXA5 HOXA3 HOXA3 GLI1 GLI1 GATA3 GATA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WT1Wilms tumor protein isoform X1. (450 aa)
SALL1LOW QUALITY PROTEIN: sal-like protein 1. (1317 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
HES1Transcription factor HES-1. (280 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SRFSerum response factor. (510 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC103085888Corticotropin-releasing factor receptor 1-like. (129 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
ANXA1Annexin. (346 aa)
NEUROG3Neurogenin-3. (216 aa)
PAX1Paired box protein Pax-1. (450 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
ONECUT2One cut domain family member 2. (320 aa)
ARMC5Armadillo repeat-containing protein 5. (942 aa)
RFX6DNA-binding protein RFX6. (923 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
LOC103070818Homeobox protein Nkx-6.1-like. (448 aa)
FOXA2Hepatocyte nuclear factor 3-beta. (466 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
SOX9Transcription factor SOX-9 isoform X1. (509 aa)
ASCL1Achaete-scute homolog 1. (227 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
HESX1Homeobox expressed in ES cells 1. (186 aa)
NF1Neurofibromin isoform X1. (2841 aa)
NR5A1Steroidogenic factor 1 isoform X1. (461 aa)
CRKLCrk-like protein. (303 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (185 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
ARID5BAT-rich interactive domain-containing protein 5B. (327 aa)
GDF11Growth/differentiation factor 11. (404 aa)
SIDT2SID1 transmembrane family member 2. (835 aa)
LOC103087126AT-rich interactive domain-containing protein 5B-like. (941 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog isoform X2. (675 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
EDN1Endothelin-1. (202 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
PAX8Paired box protein Pax-8. (288 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
GHRHSomatoliberin isoform X1. (106 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
GIPGastric inhibitory polypeptide. (144 aa)
NKX2-5Homeobox protein Nkx-2.5. (324 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
POU3F2POU domain protein. (439 aa)
LOC103088309Homeobox protein prophet of Pit-1-like. (226 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (474 aa)
LOC103077930Thyroid transcription factor 1-like isoform X2. (402 aa)
LOC103090072Cyclic AMP-responsive element-binding protein 1-like. (47 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC103086063Homeobox protein orthopedia-like. (267 aa)
PDX1Pancreas/duodenum homeobox protein 1. (286 aa)
DKK3Dickkopf-related protein 3 isoform X1. (349 aa)
LOC103078457Homeobox protein orthopedia-like. (331 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
VHLLOW QUALITY PROTEIN: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase. (219 aa)
PAX4LOW QUALITY PROTEIN: paired box 4. (478 aa)
SIX1Homeobox protein SIX1. (284 aa)
MNX1LOW QUALITY PROTEIN: motor neuron and pancreas homeobox 1. (655 aa)
EDNRAEndothelin-1 receptor isoform X2. (318 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GSX1GS homeobox 1. (263 aa)
NKX6-1Homeobox protein Nkx-6.1-like. (365 aa)
PITX1Homeobox protein. (312 aa)
ONECUT1One cut domain family member. (464 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
APOA1Apolipoprotein A-I. (265 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
FOXE1Forkhead box protein E1. (373 aa)
LHX3LIM/homeobox protein Lhx3 isoform X1. (403 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1118 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
GCM2Chorion-specific transcription factor GCMb. (505 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (452 aa)
HOXA5Homeobox protein Hox-A5. (270 aa)
HOXA3Homeobox protein Hox-A3. (385 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (26%) [HD]