STRINGSTRING
ODAM ODAM NKX2-3 NKX2-3 SMO SMO BCL2L11 BCL2L11 FGF8 FGF8 CNNM4 CNNM4 EDA EDA SOSTDC1 SOSTDC1 BMP2 BMP2 TNFSF11 TNFSF11 ANKRD11 ANKRD11 GLI3 GLI3 HDAC1 HDAC1 INHBA INHBA FAM20C FAM20C AQP1 AQP1 SNX10 SNX10 LOC103088508 LOC103088508 DLX3 DLX3 FGF4 FGF4 MSX1 MSX1 CTNNB1 CTNNB1 NGFR NGFR LOC103071971 LOC103071971 AQP3 AQP3 OSR1 OSR1 KLK5 KLK5 PAX9 PAX9 KLK4 KLK4 LAMA5 LAMA5 SSUH2 SSUH2 STIM1 STIM1 WDR72 WDR72 FGF10 FGF10 DLX1 DLX1 NF2 NF2 TGFB1 TGFB1 RUNX2 RUNX2 TP63 TP63 LOC103088826 LOC103088826 LOC103079308 LOC103079308 FST FST ID3 ID3 DLX2 DLX2 BMPR1A BMPR1A BCL11B BCL11B LAMB1 LAMB1 AXIN2 AXIN2 LOC103086357 LOC103086357 OSR2 OSR2 SHH SHH EDAR EDAR HAND2 HAND2 PHEX PHEX JAG2 JAG2 PDGFRA PDGFRA CCDC154 CCDC154 LRP4 LRP4 HAND1 HAND1 FAM20A FAM20A SLC24A4 SLC24A4 LEF1 LEF1 TSPEAR TSPEAR PPARA PPARA ANKH ANKH BCOR BCOR ROGDI ROGDI PITX2 PITX2 LOC103088795 LOC103088795 AQP5 AQP5 LOC103079743 LOC103079743 DSPP DSPP SMPD3 SMPD3 CFTR CFTR MMP20 MMP20 TCIRG1 TCIRG1 RELT RELT LHX8 LHX8 BMP7 BMP7 AMTN AMTN AMBN AMBN WNT6 WNT6 SRC SRC WNT10A WNT10A RHOA RHOA ENAM ENAM BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ODAMLOW QUALITY PROTEIN: odontogenic ameloblast-associated protein. (279 aa)
NKX2-3Homeobox protein Nkx-2.3. (365 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
CNNM4Metal transporter CNNM4. (776 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2610 aa)
GLI3Transcriptional activator GLI3. (1590 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (538 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
FAM20CExtracellular serine/threonine protein kinase FAM20C. (583 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SNX10LOW QUALITY PROTEIN: sorting nexin-10. (228 aa)
LOC103088508TNF receptor-associated factor 6-like. (251 aa)
DLX3Homeobox protein DLX-3. (287 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
MSX1Homeobox protein MSX-1. (303 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
LOC103071971Collagen alpha-1(I) chain-like. (1463 aa)
AQP3Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
KLK5LOW QUALITY PROTEIN: kallikrein-5; Belongs to the peptidase S1 family. (301 aa)
PAX9Paired box protein Pax-9 isoform X1. (342 aa)
KLK4Kallikrein-4; Belongs to the peptidase S1 family. (253 aa)
LAMA5Laminin subunit alpha-5. (3689 aa)
SSUH2Protein SSUH2 homolog. (375 aa)
STIM1Stromal interaction molecule 1 isoform X1. (785 aa)
WDR72WD repeat-containing protein 72. (1100 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
DLX1Homeobox protein DLX-1. (255 aa)
NF2LOW QUALITY PROTEIN: merlin. (592 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
RUNX2Runt-related transcription factor 2 isoform X1. (550 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
FSTFollistatin isoform X1. (344 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
DLX2LOW QUALITY PROTEIN: homeobox protein DLX-2. (335 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (902 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
AXIN2Axin-2. (846 aa)
LOC103086357Protein scribble homolog. (347 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (448 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
PHEXPhosphate-regulating neutral endopeptidase isoform X1. (749 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
CCDC154LOW QUALITY PROTEIN: coiled-coil domain-containing protein 154. (649 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1881 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
FAM20AProtein FAM20A. (521 aa)
SLC24A4Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (618 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
TSPEARThrombospondin-type laminin G domain and EAR repeat-containing protein. (670 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
ANKHProgressive ankylosis protein homolog. (492 aa)
BCORLOW QUALITY PROTEIN: BCL-6 corepressor. (1720 aa)
ROGDIProtein rogdi homolog. (287 aa)
PITX2Homeobox protein. (325 aa)
LOC103088795TNF receptor-associated factor 6-like. (315 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
LOC103079743Homeobox protein. (212 aa)
DSPPDentin sialophosphoprotein. (1110 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (654 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
MMP20Matrix metalloproteinase-20. (483 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
RELTTumor necrosis factor receptor superfamily member 19L. (429 aa)
LHX8LIM/homeobox protein Lhx8 isoform X1. (346 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
AMTNAmelotin. (240 aa)
AMBNAmeloblastin. (420 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SRCTyrosine-protein kinase. (548 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
ENAMEnamelin. (1146 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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