STRINGSTRING
RHOA RHOA FGF8 FGF8 ISL1 ISL1 BOK BOK PTPRZ1 PTPRZ1 SIX1 SIX1 HIF1A HIF1A STXBP1 STXBP1 LOC103082395 LOC103082395 PRKCG PRKCG CRLF1 CRLF1 AXL AXL PINK1 PINK1 FOXB1 FOXB1 GBA GBA MSH2 MSH2 PARK2 PARK2 ALKBH1 ALKBH1 EN2 EN2 NES NES HDGF HDGF MECP2 MECP2 LOC103090152 LOC103090152 HYOU1 HYOU1 NEFL NEFL THAP11 THAP11 EN1 EN1 KIF14 KIF14 CCL2 CCL2 NTRK1 NTRK1 SEMA3E SEMA3E MAP2K4 MAP2K4 CNTF CNTF LGMN LGMN UNC5B UNC5B GDNF GDNF NGF NGF AMBRA1 AMBRA1 PARK7 PARK7 BARHL1 BARHL1 GRN GRN SLC30A10 SLC30A10 CLN3 CLN3 LOC103077993 LOC103077993 FAIM2 FAIM2 TFAP2D TFAP2D FOXQ1 FOXQ1 ADAM8 ADAM8 PLA2G3 PLA2G3 BHLHB9 BHLHB9 LOC103068693 LOC103068693 CLCF1 CLCF1 CORO1A CORO1A DLX6 DLX6 KDR KDR TFAP2B TFAP2B CHL1 CHL1 FAM134B FAM134B KDM2B KDM2B LOC103082455 LOC103082455 PPARGC1A PPARGC1A RASA1 RASA1 LOC103072255 LOC103072255 CEBPB CEBPB VSTM2L VSTM2L DNAJC5B DNAJC5B ADNP ADNP NFATC4 NFATC4 OXR1 OXR1 KRAS KRAS CLN8 CLN8 GFRAL GFRAL IL6ST IL6ST XRCC2 XRCC2 LOC103083735 LOC103083735 MAG MAG IL27RA IL27RA NTF3 NTF3 NR4A2 NR4A2 FZD9 FZD9 ERBB3 ERBB3 BRAF BRAF HIPK2 HIPK2 CX3CR1 CX3CR1 HRAS HRAS AGAP2 AGAP2 CCND1 CCND1 CITED1 CITED1 MEF2C MEF2C PIK3CA PIK3CA SIX4 SIX4 NDNF NDNF PRKCI PRKCI POU4F1 POU4F1 GABRB2 GABRB2 GRIK2 GRIK2 NRBP2 NRBP2 BCL2 BCL2 LIG4 LIG4 VPS54 VPS54 WFS1 WFS1 F2R F2R BIRC5 BIRC5 NTF4 NTF4 DRAXIN DRAXIN SNCB SNCB LOC103082426 LOC103082426 ZPR1 ZPR1 AARS AARS PLXND1 PLXND1 JUN JUN DNAJC5 DNAJC5 SYNGAP1 SYNGAP1 FGF20 FGF20 TOX3 TOX3 TYRO3 TYRO3 DLX1 DLX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOATransforming protein RhoA isoform X1. (221 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
BOKBcl-2-related ovarian killer protein. (213 aa)
PTPRZ1Receptor-type tyrosine-protein phosphatase zeta. (2229 aa)
SIX1Homeobox protein SIX1. (284 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
LOC103082395Homeobox protein SIX4-like. (300 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CRLF1Cytokine receptor-like factor 1. (616 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (887 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (571 aa)
FOXB1Forkhead box protein B1-like. (325 aa)
GBAGlucosylceramidase. (536 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
PARK2RBR-type E3 ubiquitin transferase. (274 aa)
ALKBH1LOW QUALITY PROTEIN: alkylated DNA repair protein alkB homolog 1. (389 aa)
EN2Homeobox protein engrailed-like. (328 aa)
NESNestin; Belongs to the intermediate filament family. (1571 aa)
HDGFHepatoma-derived growth factor. (237 aa)
MECP2methyl-CpG-binding protein 2. (537 aa)
LOC103090152Forkhead box protein B1-like. (275 aa)
HYOU1Hypoxia up-regulated protein 1 isoform X1. (998 aa)
NEFLNeurofilament light polypeptide; Belongs to the intermediate filament family. (552 aa)
THAP11THAP domain-containing protein 11. (314 aa)
EN1Homeobox protein engrailed-like. (533 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1607 aa)
CCL2C-C motif chemokine. (99 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
SEMA3Esemaphorin-3E-like; Belongs to the semaphorin family. (715 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (410 aa)
CNTFCiliary neurotrophic factor. (200 aa)
LGMNLegumain. (434 aa)
UNC5BNetrin receptor UNC5B isoform X1. (935 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X1. (211 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1205 aa)
PARK7Protein DJ-1. (189 aa)
BARHL1barH-like 1 homeobox protein. (327 aa)
GRNGranulins. (587 aa)
SLC30A10Zinc transporter 10. (485 aa)
CLN3Battenin. (444 aa)
LOC103077993Gamma-aminobutyric acid receptor subunit alpha-5-like isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
FAIM2Protein lifeguard 2; Belongs to the BI1 family. (315 aa)
TFAP2DTranscription factor AP-2-delta. (452 aa)
FOXQ1Forkhead box protein Q1. (233 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (1009 aa)
PLA2G3Group 3 secretory phospholipase A2. (516 aa)
BHLHB9Protein BHLHb9. (566 aa)
LOC103068693Lysine-specific demethylase 2B-like. (224 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (215 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
DLX6Homeobox protein Dlx6a. (286 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (469 aa)
CHL1Neural cell adhesion molecule L1-like protein. (607 aa)
FAM134BProtein FAM134B isoform X1. (375 aa)
KDM2BLysine-specific demethylase 2B isoform X1. (1270 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
LOC103072255Probable alanine--tRNA ligase, chloroplastic-like; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (826 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
VSTM2LV-set and transmembrane domain-containing protein 2-like protein. (205 aa)
DNAJC5BdnaJ homolog subfamily C member 5B isoform X1. (199 aa)
ADNPActivity-dependent neuroprotector homeobox protein isoform X1. (1102 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (901 aa)
OXR1Oxidation resistance protein 1 isoform X2. (841 aa)
KRASGTPase KRas. (188 aa)
CLN8Protein CLN8. (302 aa)
GFRALLOW QUALITY PROTEIN: GDNF family receptor alpha-like. (544 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
XRCC2DNA repair protein XRCC2-like. (280 aa)
LOC103083735E3 ubiquitin-protein ligase parkin-like. (141 aa)
MAGMyelin-associated glycoprotein isoform X1. (626 aa)
IL27RAInterleukin-27 receptor subunit alpha. (656 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform X1. (609 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1180 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
HRASGTPase HRas isoform X1. (189 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like isoform X1. (1193 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (221 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
SIX4Homeobox protein SIX4-like. (786 aa)
NDNFProtein NDNF. (568 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
POU4F1POU domain protein. (388 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
GRIK2Glutamate receptor ionotropic, kainate 2-like isoform X1. (908 aa)
NRBP2Nuclear receptor-binding protein 2. (563 aa)
BCL2Apoptosis regulator Bcl-2. (232 aa)
LIG4DNA ligase. (911 aa)
VPS54Vacuolar protein sorting-associated protein 54 isoform X1. (977 aa)
WFS1Wolframin. (889 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (210 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
LOC103082426Protein lifeguard 2-like; Belongs to the BI1 family. (303 aa)
ZPR1Zinc finger protein ZPR1. (459 aa)
AARSalanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (991 aa)
PLXND1plexin-D1. (1747 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
DNAJC5dnaJ homolog subfamily C member 5. (198 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1324 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
TOX3TOX high mobility group box family member 3 isoform X1. (570 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (813 aa)
DLX1Homeobox protein DLX-1. (255 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.