STRINGSTRING
IL1B IL1B LOC103090462 LOC103090462 CLEC7A CLEC7A LOC103076141 LOC103076141 AGXT2 AGXT2 IFNG IFNG KLF2 KLF2 DDAH2 DDAH2 LOC103090933 LOC103090933 INSR INSR LOC103070382 LOC103070382 ESR1 ESR1 DDAH1 DDAH1 LOC103074137 LOC103074137 HSP90AA1 HSP90AA1 ASS1 ASS1 LOC103090292 LOC103090292 PKD2 PKD2 MMP8 MMP8 LOC103086710 LOC103086710 SMAD3 SMAD3 PTX3 PTX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
LOC103090462Argininosuccinate lyase, chloroplastic-like. (477 aa)
CLEC7AC-type lectin domain family 7 member A isoform X1. (244 aa)
LOC103076141Argininosuccinate lyase, chloroplastic-like. (464 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
KLF2Krueppel-like factor 2. (355 aa)
DDAH2N(G),N(G)-dimethylarginine dimethylaminohydrolase 2. (285 aa)
LOC103090933Ornithine aminotransferase-like; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
LOC103070382Argininosuccinate synthase, chloroplastic-like. (380 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
DDAH1N(G),N(G)-dimethylarginine dimethylaminohydrolase 1. (185 aa)
LOC103074137Argininosuccinate synthase, chloroplastic-like. (273 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (732 aa)
ASS1Argininosuccinate synthase. (412 aa)
LOC103090292Argininosuccinate lyase-like isoform X1. (464 aa)
PKD2LOW QUALITY PROTEIN: polycystin-2. (963 aa)
MMP8Neutrophil collagenase. (468 aa)
LOC103086710Argininosuccinate synthase, chloroplastic-like. (405 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PTX3Pentraxin-related protein PTX3. (382 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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